Improvement of hepatic and extrahepatic functions and anti-inflammatory effects of nitazoxanide in disease models of LPS-induced systemic inflammation and acute-on-chronic liver failure

Autor: Vanessa Legry, Philippe Delataille, Maryse Malysiak, Valérie Daix, Simon Debaecker, Bart Staels, Remy Hanf, Dean Hum

Publikováno v: Journal of Hepatology. 77:S359-S360

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9037c7f17564e422b43e6537c66a022d
https://doi.org/10.1016/s0168-8278(22)01074-1

Factors to Consider in Development of Drugs for Pediatric Nonalcoholic Fatty Liver Disease

Autor: Miriam B. Vos, Lara Dimick-Santos, Ruby Mehta, Stephanie O. Omokaro, Johannes Taminiau, Elmer Schabel, David E. Kleiner, Peter Szitanyi, Piotr Socha, Jeffrey B. Schwimmer, Stephanie Noviello, Debra G. Silberg, Richard Torstenson, Veronica Miller, Joel E. Lavine, Nathalie Adda, William Baldyga, Rajarshi Banerjee, Cynthia Behling, Sherif Boulos, Gary Burgess, Dania Calboli, Edgar Charles, Rose Christian, Claude Cohen-Bacrie, Doina Cosma-Roman, Claus-Peter Danzer, Ingrid Delaet, Mark Delegge, Nicholas DiProspero, Kathleen Donohue, Laurent Fischer, Emer Fitzpatrick, Michael Fried, David Hagerty, Paula Hale, Keri Hildick, Dean Hum, Khurram Jamil, Lijuan Jiang, Saul Karpen, Matt Kelly, Rohit Kohli, Kattayoun Kordy, Nancy Krieger, Joel Lavine, Lois Lee, Eric Lefebvre, Patricia Lopez, Erica Lyons, Laura Malahias, Sophie Megnien, Peter Mesenbrink, Pansy Minnick, Christine Murray, Tien Nghiem, Nikki Nicholson, Wenjie Pang, Lisa Percival, Dan Peres, Margaret Powell, Dragos Roman, Mark Root, Claire Sampson, Arun Sanyal, Kathleen Schwarz, Star Seyedkazemi, David Shapiro, Reshma Shringarpure, Debra Silberg, Edward Smith, Robert Squires, William Treem, Pamela Vig, Miriam Vos, Mason Yamashita, Michael Zemel

Publikováno v: Gastroenterology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b982e78cf5b668a605de3b462e0f3fec
https://pubmed.ncbi.nlm.nih.gov/31520612

Baseline Parameters in Clinical Trials for Nonalcoholic Steatohepatitis: Recommendations From the Liver Forum

Autor: Yuval A. Patel, Joanne C. Imperial, Andrew J. Muir, Quentin M. Anstee, David DeBrota, Lara Dimick-Santos, Claudia Filozof, Ruby Mehta, Arun J. Sanyal, Elmer Schabel, Brent A. Neuschwander-Tetri, Veronica Miller, Sander Bangma, Melanie Baxter, Sherif Boulos, Gary Burgess, Manu Chakravarthy, Rose Christian, Anthony Coombs, Goran Gannedahl, Richard Herrmann, Dean Hum, Joanne Imperial, Stuart Kendrick, Leigh MacConell, Sophie Megnien, Andrew Muir, Yuval Patel, Dan Peres, Stephen Rossi, Arun Sanyal, David Shapiro, Tim St Pierre, Michael Zemel

Nonalcoholic fatty liver disease (NAFLD) is the most prevalent form of chronic liver disease worldwide and is an increasing cause of liver-related morbidity and mortality. Nonalcoholic steatohepatitis (NASH), the progressive histological subtype of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c0e8b8f543a51c1159349167e1f477
https://europepmc.org/articles/PMC5861348/

Extensive mapping of PPAR binding to genomic DNA

Autor: Ronni Nielsen, Thomas Åskov Pedersen, Luisa Trindade, Marc van Driel, Lars Grøntved, Brozek, John J., Bart Staels, Dean Hum, Henk Stunnenberg, Susanne Mandrup

Publikováno v: Nielsen, R, Pedersen, T Å, Trindade, L, van Driel, M, Grøntved, L, Brozek, J J, Staels, B, Hum, D, Stunnenberg, H & Mandrup, S 2008, ' Extensive mapping of PPAR binding to genomic DNA ', Nuclear Receptors: Structure and Function in health and disease, Gardone, Italy, 02/05/2007-05/05/2007 .
University of Southern Denmark

The peroxisome proliferator-activated receptor (PPAR) transcription factors a, d and g are members of the nuclear hormone receptor super family. The PPARs bind regulatory DNA elements (PPREs) as heterodimers with the retinoid X receptor (RXR) and the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4072215077e47a68283b429e97215b02
https://portal.findresearcher.sdu.dk/da/publications/bcc47de0-e476-11dc-a57f-000ea68e967b

New liver function of nuclear receptors FXR and Rev-Erb Alpha

Autor: Porez, Geoffrey

Publikováno v: Médecine humaine et pathologie. Université du Droit et de la Santé-Lille II, 2014. Français. ⟨NNT : 2014LIL2S015⟩

Orosomucoïdes, members of the superfamily of lipocalines, are among proteins plasmatiques the most plentiful. They are proteins of the acute(sharp) phase of the inflammation secreted by hépatocytes in answer to a stress (inflammation, cancer, cirrh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1398::511f935b39570d7b863eb41286f2cff0
https://theses.hal.science/tel-01370819