Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Dean F. Ashley"'
Autor:
Ben D. McNally, Dean F. Ashley, Lea Hänschke, Hélène N. Daou, Nicole T. Watt, Steven A. Murfitt, Amanda D. V. MacCannell, Anna Whitehead, T. Scott Bowen, Francis W. B. Sanders, Michele Vacca, Klaus K. Witte, Graeme R. Davies, Reinhard Bauer, Julian L. Griffin, Lee D. Roberts
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Endoplasmic Reticulum stress induces cell non-autonomous Unfolded Protein Response (UPR) activation. Here the authors show that long-chain ceramides are secreted from muscle cells in extracellular vesicles and induce cell non-autonomous UPR activatio
Externí odkaz:
https://doaj.org/article/e431ba3360bc41d78c30c04a825835be
Autor:
Ben D, McNally, Dean F, Ashley, Lea, Hänschke, Hélène N, Daou, Nicole T, Watt, Steven A, Murfitt, Amanda D V, MacCannell, Anna, Whitehead, T Scott, Bowen, Francis W B, Sanders, Michele, Vacca, Klaus K, Witte, Graeme R, Davies, Reinhard, Bauer, Julian L, Griffin, Lee D, Roberts
Publikováno v:
Nature communications. 13(1)
The endoplasmic reticulum (ER) regulates cellular protein and lipid biosynthesis. ER dysfunction leads to protein misfolding and the unfolded protein response (UPR), which limits protein synthesis to prevent cytotoxicity. Chronic ER stress in skeleta