Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Dean A. Tolla"'
Autor:
Dean A. Tolla, Michael A. Savageau
Publikováno v:
Molecular Microbiology. 79:149-165
Summary The FNR protein in Escherichia coli is an O2 sensor that modifies global gene expression to adapt the cell to anaerobic growth. Regulation of FNR involves continuous cycling of the protein between its active and inactive states under aerobic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9194e2d1dcf38a1414b907ceb5f7ea23
https://doi.org/10.1111/j.1365-2958.2010.07437.x
https://doi.org/10.1111/j.1365-2958.2010.07437.x
Autor:
Michael A. Savageau, Dean A. Tolla
Publikováno v:
Journal of Molecular Biology. 397:893-905
The FNR (fumarate nitrate reduction) protein plays a central role in the global oxygen response of a variety of bacteria. In Escherichia coli, FNR is the master transcriptional regulator of the transition between aerobic and anaerobic growth. Regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::737633c493bf098ff1d64767c4302298
https://doi.org/10.1016/j.jmb.2010.02.015
https://doi.org/10.1016/j.jmb.2010.02.015
Publikováno v:
Proceedings of the National Academy of Sciences. 106:6435-6440
One of the major unsolved problems of modern biology is deep understanding of the complex relationship between the information encoded in the genome of an organism and the phenotypic properties manifested by that organism. Fundamental advances must b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b487833c21ec960bf04b31e25f01a59e
https://doi.org/10.1073/pnas.0809869106
https://doi.org/10.1073/pnas.0809869106
Publikováno v:
Molecular bioSystems, vol 11, iss 7
In this report, we characterize the design principles of futile cycling in providing rapid adaptation by regulatory proteins that act as environmental sensors. In contrast to the energetically wasteful futile cycles that are avoided in metabolic path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24dddc960856e72a13a9f6eaf119867b
https://escholarship.org/uc/item/9jd3n8sk
https://escholarship.org/uc/item/9jd3n8sk
Autor:
Dean A, Tolla, Michael A, Savageau
Publikováno v:
Molecular microbiology. 79(1)
The FNR protein in Escherichia coli is an O(2) sensor that modifies global gene expression to adapt the cell to anaerobic growth. Regulation of FNR involves continuous cycling of the protein between its active and inactive states under aerobic condit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::50bef9870ee33184960dc76915bcdb22
https://pubmed.ncbi.nlm.nih.gov/21166900
https://pubmed.ncbi.nlm.nih.gov/21166900