Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Dean A A Myles"'
Autor:
Jonathan D Nickels, Sneha Chatterjee, Christopher B Stanley, Shuo Qian, Xiaolin Cheng, Dean A A Myles, Robert F Standaert, James G Elkins, John Katsaras
Publikováno v:
PLoS Biology, Vol 15, Iss 5, p e2002214 (2017)
Examining the fundamental structure and processes of living cells at the nanoscale poses a unique analytical challenge, as cells are dynamic, chemically diverse, and fragile. A case in point is the cell membrane, which is too small to be seen directl
Externí odkaz:
https://doaj.org/article/d33fb552170248f09f35b50749122267
Autor:
Jahaun Azadmanesh, Katelyn Slobodnik, Lucas R. Struble, William E. Lutz, Leighton Coates, Kevin L. Weiss, Dean A. A. Myles, Thomas Kroll, Gloria E. O. Borgstahl
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Human manganese superoxide dismutase (MnSOD) is a crucial oxidoreductase that maintains the vitality of mitochondria by converting superoxide (O2 ●−) to molecular oxygen (O2) and hydrogen peroxide (H2O2) with proton-coupled electron tran
Externí odkaz:
https://doaj.org/article/44171d554d4e49eab2348ae9c046dfe2
Autor:
Jonathan D. Nickels, Suresh Poudel, Sneha Chatterjee, Abigail Farmer, Destini Cordner, Shawn R. Campagna, Richard J. Giannone, Robert L. Hettich, Dean A. A. Myles, Robert F. Standaert, John Katsaras, James G. Elkins
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Developing cultivation methods that yield chemically and isotopically defined fatty acid (FA) compositions within bacterial cytoplasmic membranes establishes an in vivo experimental platform to study membrane biophysics and cell membrane regulation u
Externí odkaz:
https://doaj.org/article/e29f17aa583744b8a63cdd8b25a63fa2
Autor:
Josh Pierce, Dean A. A. Myles
Publikováno v:
Proceedings of the 24th International Spin Symposium (SPIN2021).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fa2bcf32dab0569e00f56210a4ba9d8
https://doi.org/10.7566/jpscp.37.011006
https://doi.org/10.7566/jpscp.37.011006
Publikováno v:
Nature Reviews Methods Primers. 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79dedc9c8b8fe006e6699dc0e7dc67e4
https://doi.org/10.1038/s43586-022-00112-y
https://doi.org/10.1038/s43586-022-00112-y
Publikováno v:
Crystals, Vol 8, Iss 10, p 388 (2018)
The IMAGINE and MaNDi instruments, located at Oak Ridge National Laboratory High Flux Isotope Reactor and Spallation Neutron Source, respectively, are powerful tools for determining the positions of hydrogen atoms in biological macromolecules and the
Externí odkaz:
https://doaj.org/article/e89ca3748d4348b0b8ea6f4e14ae0ffb
Autor:
Dean A. A. Myles, Kenneth W. Herwig, A. Wonder, Jinkui Zhao, A. Jennings, Lowell Crow, Lee Robertson, Le Li, Flora Meilleur, M. Edwards, Robert F. Standaert, A. Jones, Matthew J. Cuneo, J. Pierce
Publikováno v:
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 940:430-434
The sensitivity of Neutron Macromolecular Crystallography to the presence of hydrogen makes it a powerful tool to complement X-ray crystallographic studies using protein crystals. The power of this technique is currently limited by the relative low n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1773f5a748af4cc582c7c78878da5cdf
https://doi.org/10.1016/j.nima.2019.06.023
https://doi.org/10.1016/j.nima.2019.06.023
Autor:
Gregory S. Orf, Sudipa Ghimire-Rijal, Dean A. A. Myles, Matthew J. Cuneo, Brinda Selvaraj, Xun Lu, Flora Meilleur, Robert E. Blankenship
Publikováno v:
Acta Crystallogr F Struct Biol Commun
The Fenna–Matthews–Olson protein from Prosthecochloris aestuarii (PaFMO) has been crystallized in a new form that is amenable to high-resolution X-ray and neutron analysis. The crystals belonged to space group H3, with unit-cell parameters a = b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de88c36a435bbbf7895f3e77c32b43a
https://doi.org/10.1107/s2053230x19000724
https://doi.org/10.1107/s2053230x19000724
Publikováno v:
Journal of physics. Condensed matter : an Institute of Physics journal. 33(42)
The continuing increase in the brilliance of synchrotron radiation beamlines allows for many new and exciting experiments that were impossible before the present generation of synchrotron radiation sources came on line. However, the exposure to such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c520c084e76c3557928c4a48acb9d5dc
https://pubmed.ncbi.nlm.nih.gov/34298526
https://pubmed.ncbi.nlm.nih.gov/34298526
Autor:
Joshua, Pierce, Matthew J, Cuneo, Anna, Jennings, Le, Li, Flora, Meilleur, Jinkui, Zhao, Dean A A, Myles
Publikováno v:
Methods in enzymology. 634
Dynamic nuclear polarization (DNP) can provide a powerful means to amplify neutron diffraction from biological crystals by 10-100-fold, while simultaneously enhancing the visibility of hydrogen by an order of magnitude. Polarizing the neutron beam an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::337b822aa35a26504e994c6277d08362
https://pubmed.ncbi.nlm.nih.gov/32093831
https://pubmed.ncbi.nlm.nih.gov/32093831