Metal Complexes as Antifungals? From a Crowd-Sourced Compound Library to the First

Autor: Angelo, Frei, Alysha G, Elliott, Alex, Kan, Hue, Dinh, Stefan, Bräse, Alice E, Bruce, Mitchell R, Bruce, Feng, Chen, Dhirgam, Humaidy, Nicole, Jung, A Paden, King, Peter G, Lye, Hanna K, Maliszewska, Ahmed M, Mansour, Dimitris, Matiadis, María Paz, Muñoz, Tsung-Yu, Pai, Shyam, Pokhrel, Peter J, Sadler, Marina, Sagnou, Michelle, Taylor, Justin J, Wilson, Dean, Woods, Johannes, Zuegg, Wieland, Meyer, Amy K, Cain, Matthew A, Cooper, Mark A T, Blaskovich

Publikováno v: JACS Au

[Image: see text] There are currently fewer than 10 antifungal drugs in clinical development, but new fungal strains that are resistant to most current antifungals are spreading rapidly across the world. To prevent a second resistance crisis, new cla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7cc56d82b7ca779facf23c5e5919ab6c
https://pubmed.ncbi.nlm.nih.gov/36311838

The Importance of Acetonitrile in the Pharmaceutical Industry and Opportunities for its Recovery from Waste

Autor: Ian F. McConvey, Dean Woods, Paul Nancarrow, Quan Gan, Moira Lewis

Publikováno v: McConvey, I F, Woods, D, Lewis, M, Gan, Q & Nancarrow, P 2012, ' The Importance of Acetonitrile in the Pharmaceutical Industry and Opportunities for its Recovery from Waste ', Organic Process Research & Development, vol. 16, no. 4, pp. 612-624 . https://doi.org/10.1021/op2003503

Acetonitrile is regarded as a key solvent in the pharmaceutical industry. However, the volatility in acetonitrile supply in recent years, coupled with its relatively poor environmental profile, has presented significant challenges to its use in manuf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76a86625e1dc732a67f736da3a4b0fb0
https://pure.qub.ac.uk/en/publications/the-importance-of-acetonitrile-in-the-pharmaceutical-industry-and-opportunities-for-its-recovery-from-waste(de533647-f193-49f2-b6e7-9eee75cf765f).html