Zobrazeno 1 - 10
of 290
pro vyhledávání: '"Dean, Williams"'
Autor:
Moran Frenkel-Pinter, Marcos Bouza, Facundo M. Fernández, Luke J. Leman, Loren Dean Williams, Nicholas V. Hud, Aikomari Guzman-Martinez
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
One of the early processes enabling the origins of life is thought to be the condensation of building blocks into oligomers and polymers. In this article, the authors report the synthesis of thiodepsipeptides and HS-peptides under mild temperatures a
Externí odkaz:
https://doaj.org/article/df6d52a3f47240ee80e477d8bbe3f713
Autor:
Dean WIlliams
Leaders today—whether in corporations or associations, nonprofits or nations—face massive, messy, multidimensional problems. No one person or group can possibly solve them—they require the broadest possible cooperation. But, says Harvard schola
Autor:
Blake A. Sweeney, David Hoksza, Eric P. Nawrocki, Carlos Eduardo Ribas, Fábio Madeira, Jamie J. Cannone, Robin Gutell, Aparna Maddala, Caeden D. Meade, Loren Dean Williams, Anton S. Petrov, Patricia P. Chan, Todd M. Lowe, Robert D. Finn, Anton I. Petrov
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Non-coding RNA function is poorly understood, partly due to the challenge of determining RNA secondary (2D) structure. Here, the authors present a framework for the reproducible prediction and visualization of the 2D structure of a wide array of RNAs
Externí odkaz:
https://doaj.org/article/08c55853e54b4060954e1a43ffedc3a6
Autor:
Bassel Akache, Andrew J. Read, Renu Dudani, Blair A. Harrison, Dean Williams, Lise Deschatelets, Yimei Jia, Vandana Chandan, Felicity C. Stark, Gerard Agbayani, Shawn R. Makinen, Usha D. Hemraz, Edmond Lam, Sophie Régnier, Wei Zou, Peter D. Kirkland, Michael J. McCluskie
Publikováno v:
Vaccines, Vol 11, Iss 6, p 1043 (2023)
Vaccines play an important role in maintaining human and animal health worldwide. There is continued demand for effective and safe adjuvants capable of enhancing antigen-specific responses to a target pathogen. Rabbit hemorrhagic disease virus (RHDV)
Externí odkaz:
https://doaj.org/article/8033a136f9c84c7da76024c305c13447
Autor:
Moran Frenkel-Pinter, Jay W. Haynes, Ahmad M. Mohyeldin, Martin C, Alyssa B. Sargon, Anton S. Petrov, Ramanarayanan Krishnamurthy, Nicholas V. Hud, Loren Dean Williams, Luke J. Leman
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Cooperative relationships are widespread among different classes of biopolymers and are predicted to have existed during emergence of life. This study shows that proto-peptides engage in mutually stabilizing interactions with RNA, providing support f
Externí odkaz:
https://doaj.org/article/ce86f8db408449cc807579afb0ac893f
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 10 (2021)
We have developed the program TwinCons, to detect noisy signals of deep ancestry of proteins or nucleic acids. As input, the program uses a composite alignment containing pre-defined groups, and mathematically determines a ‘cost’ of transforming
Externí odkaz:
https://doaj.org/article/e964b131d31148a489815dceb4e20530
Autor:
Rebecca Guth-Metzler, Ahmad Mohyeldin Mohamed, Elizabeth T Cowan, Ashleigh Henning, Chieri Ito, Moran Frenkel-Pinter, Roger M Wartell, Jennifer B Glass, Loren Dean Williams
Publikováno v:
Nucleic Acids Research. 51:3529-3539
Magnesium, the most abundant divalent cation in cells, catalyzes RNA cleavage but also promotes RNA folding. Because folding can protect RNA from cleavage, we predicted a ‘Goldilocks landscape’, with local maximum in RNA lifetime at Mg2+ concentr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81e5b55ecfd5fda3cfd86e952c2af736
https://doi.org/10.1093/nar/gkad124
https://doi.org/10.1093/nar/gkad124
Autor:
Moran Frenkel-Pinter, Kaitlin C. Jacobson, Jonathan Eskew-Martin, Jay G. Forsythe, Martha A. Grover, Loren Dean Williams, Nicholas V. Hud
Publikováno v:
Life, Vol 12, Iss 2, p 265 (2022)
The origin of biopolymers is a central question in origins of life research. In extant life, proteins are coded linear polymers made of a fixed set of twenty alpha-L-amino acids. It is likely that the prebiotic forerunners of proteins, or protopeptid
Externí odkaz:
https://doaj.org/article/b72948f0feba4f9bbc863250f99e04f8
Publikováno v:
Nucleic Acids Research. 50:10717-10732
The ribosomal core is universally conserved across the tree of life. However, eukaryotic ribosomes contain diverse rRNA expansion segments (ESs) on their surfaces. Sites of ES insertions are predicted from sites of insertion of micro-ESs in archaea.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc63f7e1494daa9cfd0aedb9810503b1
https://doi.org/10.1093/nar/gkac844
https://doi.org/10.1093/nar/gkac844
Thinning Influences Wood Properties of Plantation-Grown Eucalyptus nitens at Three Sites in Tasmania
Autor:
Vilius Gendvilas, Geoffrey M. Downes, Mark Neyland, Mark Hunt, Peter A. Harrison, Andrew Jacobs, Dean Williams, Julianne O’Reilly-Wapstra
Publikováno v:
Forests, Vol 12, Iss 10, p 1304 (2021)
Thinning of forestry plantations is a common silviculture practice to increase growth rates and to produce larger dimension logs. The wood properties, basic density and stiffness, are key indicators of the suitability of timber for particular purpose
Externí odkaz:
https://doaj.org/article/2114e709c7534536b39df243a96cb5c7