Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Dean, Thumkeo"'
Autor:
Siwakorn Punyawatthananukool, Ryuma Matsuura, Thamrong Wongchang, Nao Katsurada, Tatsuaki Tsuruyama, Masaki Tajima, Yutaka Enomoto, Toshio Kitamura, Masahiro Kawashima, Masakazu Toi, Koji Yamanoi, Junzo Hamanishi, Shigeo Hisamori, Kazutaka Obama, Varodom Charoensawan, Dean Thumkeo, Shuh Narumiya
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract While prostaglandin E2 (PGE2) is produced in human tumor microenvironment (TME), its role therein remains poorly understood. Here, we examine this issue by comparative single-cell RNA sequencing of immune cells infiltrating human cancers and
Externí odkaz:
https://doaj.org/article/6372a16d96814e07bbc71baade810603
Autor:
Takahiro Akamine, Takeshi Terabayashi, Takako Sasaki, Riku Hayashi, Ichitaro Abe, Fumihiro Hirayama, Shin‐ichi Nureki, Masahito Ikawa, Haruhiko Miyata, Akinori Tokunaga, Takashi Kobayashi, Katsuhiro Hanada, Dean Thumkeo, Shuh Narumiya, Toshimasa Ishizaki
Publikováno v:
FEBS Open Bio, Vol 14, Iss 6, Pp 906-921 (2024)
The Ras homology (Rho) family of GTPases serves various functions, including promotion of cell migration, adhesion, and transcription, through activation of effector molecule targets. One such pair of effectors, the Rho‐associated coiled‐coil kin
Externí odkaz:
https://doaj.org/article/55c8cc91eaf9494c8af4f125e026844e
Autor:
Ashton L. Sigler, Scott B. Thompson, Logan Ellwood-Digel, Adithan Kandasamy, Mary J. Michaels, Dean Thumkeo, Shuh Narumiya, Juan C. Del Alamo, Jordan Jacobelli
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Lymphocyte trafficking and migration through tissues is critical for adaptive immune function and, to perform their roles, T cells must be able to navigate through diverse tissue environments that present a range of mechanical challenges. T cells pre
Externí odkaz:
https://doaj.org/article/8d8a242143d24c529f8431db63d56272
Autor:
Tetsuya Watabe, Shinya Yamahira, Kanako Takakura, Dean Thumkeo, Shuh Narumiya, Michiyuki Matsuda, Kenta Terai
Publikováno v:
eLife, Vol 12 (2024)
Prostaglandin E2 (PGE2) is a key player in a plethora of physiological and pathological events. Nevertheless, little is known about the dynamics of PGE2 secretion from a single cell and its effect on the neighboring cells. Here, by observing confluen
Externí odkaz:
https://doaj.org/article/150e6e73c8384e599c47c581550169ca
Autor:
Thamrong Wongchang, Panwadee Pluangnooch, Suradej Hongeng, Adisak Wongkajornsilp, Dean Thumkeo, Kitipong Soontrapa
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Allergic contact dermatitis (ACD) is a type IV hypersensitivity mainly mediated by Th1/Th17 immune response. Topical corticosteroid is currently the first-line treatment for allergic contact dermatitis (ACD) and systemic administration of im
Externí odkaz:
https://doaj.org/article/00481b3bfc8d41478b46baff6fcff0a7
Autor:
Sigler, Ashton L., Thompson, Scott B., Ellwood-Digel, Logan, Kandasamy, Adithan, Michaels, Mary J., Dean Thumkeo, Shuh Narumiya, Del Alamo, Juan C., Jacobelli, Jordan
Publikováno v:
Frontiers in Immunology; 2024, p1-21, 21p
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101906- (2022)
Summary: Here, we describe a protocol for single-cell isolation from the primary culture of normal human epidermal keratinocytes derived from neonatal foreskin. The cell culture conditions have been optimized for inducing expression of keratinocyte d
Externí odkaz:
https://doaj.org/article/c207a63beeaf40e28b314f36c206ddd9
Autor:
Ratklao Siriwach, Anh Quynh Ngo, Makio Higuchi, Kentaro Arima, Satoko Sakamoto, Akira Watanabe, Shuh Narumiya, Dean Thumkeo
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104130- (2022)
Summary: Keratinocyte differentiation is an intricate process that is regulated by multiple mediators. Using cultured human keratinocytes, we found that lysophosphatidic acid (LPA) induced the differentiation of a previously unsuspected keratinocyte
Externí odkaz:
https://doaj.org/article/97cf8e5bf9d5453188f35d32b6dbfe81
Autor:
Tetsuya Watabe, Shinya Yamahira, Kanako Takakura, Dean Thumkeo, Shuh Narumiya, Michiyuki Matsuda, Kenta Terai
Publikováno v:
eLife; 1/26/2024, p1-19, 19p
Autor:
Tetsuya Watabe, Shinya Yamahira, Kanako Takakura, Dean Thumkeo, Shuh Narumiya, Michiyuki Matsuda, Kenta Terai
Prostaglandin E2 (PGE2) is a key player in a plethora of physiological and pathological events. Nevertheless, little is known about the dynamics of PGE2 secretion from a single cell and its effect on the neighboring cells. Here, by observing confluen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449d5c54b53d8b28456c485ea6b2255c
https://doi.org/10.7554/elife.86727.1
https://doi.org/10.7554/elife.86727.1
