Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Dean, Engelhardt"'
Autor:
Yaron Ilan, M Gomori, Barbara Thalenfeld, Dean Engelhardt, Eran Elinav, Oren Shibolet, Ruslana Alper, Elazar Rabbani, M. Margalit, Miri Sklair-Levy, Orit Pappo
Publikováno v:
The Journal of Pathology. 209:121-128
The aim of this study was to determine the effect of adoptive transfer of regulatory natural killer T (NKT) lymphocytes on the metabolic disorder in leptin-deficient ob/ob mice, which feature depletion and defective function of NKT and CD4 lymphocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb46030dbee296f2ecd380a7d788665
https://doi.org/10.1002/path.1950
https://doi.org/10.1002/path.1950
Autor:
Maya, Margalit, Samir, Abu Gazala, Samir Abu, Ghazala, Ruslana, Alper, Eran, Elinav, Athalia, Klein, Victoria, Doviner, Yoav, Sherman, Barbara, Thalenfeld, Dean, Engelhardt, Elazar, Rabbani, Yaron, Ilan
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 289:G917-G925
Concanavalin A (ConA) induces natural killer T (NKT) cell-mediated liver damage. Glucocerebroside (GC) is a naturally occurring glycolipid. Our aims were to determine the effect of GC in a murine model of ConA-induced hepatitis. Mice in groups A and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e7f0503b0a1cfbac61a4fd0b73cc81d
https://doi.org/10.1152/ajpgi.00105.2005
https://doi.org/10.1152/ajpgi.00105.2005
Autor:
Elazar Rabbani, Oren Shibolet, Ruslana Alper, Eran Elinav, Yaron Ilan, Barbara Thalenfeld, Maya Margalit, Dean Engelhardt, Athalia Klein
Publikováno v:
International Journal of Cancer. 115:443-449
NKT cells are a regulatory subset of T lymphocytes with immune modulatory effects and an important role in anti-tumor immunity. The feasibility of “ex-vivo education” of NKT cells has recently been demonstrated. To evaluate the anti-tumor effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6c54d0b053e29ed4a265045cf2279c3
https://doi.org/10.1002/ijc.20889
https://doi.org/10.1002/ijc.20889
Autor:
Yaron Ilan, Meir Ohana, Ruslana Alper, Arnon Nagler, Elazar Rabbani, Victoria Doviner, Yoav Sherman, Rifaat Safadi, Dean Engelhardt, M. Margalit
Publikováno v:
Bone Marrow Transplantation. 35:191-197
Summary: Natural killer T (NKT) lymphocyte cells are a subset of regulatory lymphocytes with important immunemodulatory effects. Our aim was to evaluate the effect of transplantation of NKT lymphocytes on graft versus host disease (GVHD) in a murine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29615f4537dc14d820f2deb19260d408
https://doi.org/10.1038/sj.bmt.1704719
https://doi.org/10.1038/sj.bmt.1704719
Autor:
Lydia Zolotarov, Shivti Trop, Elazar Rabbani, Yaron Ilan, Dean Engelhardt, Oren Shibolet, Barbara Thalenfeld, Ruslana Alper
Publikováno v:
Clinical Immunology. 111:82-92
The liver was previously suggested as a site of lymphocyte clearance. Liver-associated lymphocytes that express NK1.1 marker (NKT LAL) play a role in immune modulation. Aim: To determine the role of the liver and of NKT LAL in determining the CD4+/CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24d1094d6fad54fbe5aa1450c8d07435
https://doi.org/10.1016/j.clim.2003.12.001
https://doi.org/10.1016/j.clim.2003.12.001
Autor:
Barbara Thalenfeld, Yaron Ilan, Dean Engelhardt, Elazar Rabbani, Lydia Zolotarov, Ruslana Alper, Oren Shibolet, Athalia Klein, Yossef Kalish
Publikováno v:
Journal of Leukocyte Biology. 75:76-86
T lymphocyte-expressing natural killer (NK) cell markers (NKT cells) play a role in immune regulation. Our aim was to evaluate the in vivo effect of adoptive transfer of immune-programmed NKT cells. Colitis was induced in C57/B6 mice by 2,4,6-trinitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d140286039bc2d4845495b229562f366
https://doi.org/10.1189/jlb.0703351
https://doi.org/10.1189/jlb.0703351
Autor:
Ruslana Alper, Elazar Rabbani, Yaron Ilan, Arnon Nagler, V Doviner, Meir Ohana, Y Sherman, Dean Engelhardt
Publikováno v:
Bone Marrow Transplantation. 32:363-369
Graft-versus-host disease (GVHD) is the major obstacle for successful allogeneic stem cell transplantation (SCT). Morbidity and mortality are high, and novel therapeutic strategies are required. Current therapy, which is based mainly on immunosuppres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04bcf464a51a431ef95dad68da30fa73
https://doi.org/10.1038/sj.bmt.1704145
https://doi.org/10.1038/sj.bmt.1704145
Autor:
Yoram Menachem, Roslana Alper, Athalia Klein, Olga Kolker, Yaron Ilan, Oren Shibolet, Elazar Rabbani, Dean Engelhardt
Publikováno v:
Microbes and Infection. 5:807-813
Oral tolerance is the induction of immune hyporesponsiveness to orally administered antigens. It was described in association with a decrease in interferon gamma (IFNgamma) production by activated T cells. To determine the role of IFNgamma and IL10 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f2d4ff89054be02ce4a4274bf401ecd
https://doi.org/10.1016/s1286-4579(03)00147-3
https://doi.org/10.1016/s1286-4579(03)00147-3
Autor:
Judith Diment, Ruslana Alper, Dean Engelhardt, Amir Shlomai, Yaron Ilan, Elazar Rabbani, Shivti Trop, Oded Jurim, Israel Gotsman
Publikováno v:
The Journal of Pathology. 195:498-507
The imbalance between Th1 pro-inflammatory and Th2 anti-inflammatory cytokine-producing cells plays a major role in the pathogenesis of inflammatory bowel disease (IBD). Induction of oral tolerance to colitis-extracted proteins was previously shown t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bebe4c4760e3881a86886222cbf1eda7
https://doi.org/10.1002/path.974
https://doi.org/10.1002/path.974
Autor:
Jayanta Roy Chowdhury, Dean Engelhardt, Michael Zeira, Meir Ohana, Arnon Nagler, Orit Pappo, Namita Roy Chowdhury, Uri Abadi, Yaron Ilan, Mark Pines, Elazar Rabbani
Publikováno v:
Hepatology. 31:641-648
In chronic graft versus host disease (cGVHD), an immune attack by transplanted donor lymphocytes results in damage of host target organs. A disbalance between proinflammatory (Th1) and anti-inflammatory cytokines (Th2) plays an important role in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34bd7cc9f2e0541e85fc85fcde4378f6
https://doi.org/10.1002/hep.510310314
https://doi.org/10.1002/hep.510310314