Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Dea Nagy"'
Autor:
Kyung Park, Scott A. Tomlins, Kumaran M. Mudaliar, Ya-Lin Chiu, Raquel Esgueva, Rohit Mehra, Khalid Suleman, Sooryanarayana Varambally, John C. Brenner, Theresa MacDonald, Abhishek Srivastava, Ashutosh K. Tewari, Ubaradka Sathyanarayana, Dea Nagy, Gary Pestano, Lakshmi P. Kunju, Francesca Demichelis, Arul M. Chinnaiyan, Mark A. Rubin
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 7, Pp 590-598 (2010)
TMPRSS2-ERG gene fusions occur in 50% of prostate cancers and result in the overexpression of a chimeric fusion transcript that encodes a truncated ERG product. Previous attempts to detect truncated ERG products have been hindered by a lack of specif
Externí odkaz:
https://doaj.org/article/cfc3c5a0b7c34ac081270a606a5d9694
Autor:
Krys S. Bankiewicz M.D., Ph.D., John Bringas, Phillip Pivirotto, Ethan Kutzscher, Dea Nagy, Marina E. Emborg
Publikováno v:
Cell Transplantation, Vol 9 (2000)
Intracerebral grafting combined with gene transfer may provide a powerful technique for local delivery of therapeutic agents into the CNS. The present study was undertaken to: (i) develop a reliable and reproducible automated cell implantation system
Externí odkaz:
https://doaj.org/article/be12c79abbcd4f39b3267dc654b3efcb
Autor:
Janet Cunningham, Yoshitsugu Oiwa, Dea Nagy, Greg Podsakoff, Peter Colosi, Krys S. Bankiewicz M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 9 (2000)
Adeno-associated virus (AAV)-based vectors are being tested in animal models as viable treatments for glioma and neurodegenerative disease and could potentially be employed to target a variety of central nervous system disorders. The relationship bet
Externí odkaz:
https://doaj.org/article/3c152eb4eca0457097ebda54d5f9cdce
Autor:
Pavani Chalasani, Shalini Singh, Robert B. Livingston, Dea Nagy, Michael Barnes, AF Baker, R Ridder, E Weterings, Tom Grogan, Ray B. Nagle, S Kandavel
Publikováno v:
Cancer Research. 76:P4-07
Background: Homologous recombination deficiency (HRD) in cancer cells can occur due to mutations (germline or sporadic), methylation or other epigenetic causes. HRD leads to a defect in the conservative, error-free DNA repair mechanism and is associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c22301c4a5de632d0d2cfb037fafe681
https://doi.org/10.1158/1538-7445.sabcs15-p4-07-07
https://doi.org/10.1158/1538-7445.sabcs15-p4-07-07
Autor:
Laura Brosh, Bruce L. Dalkin, Kate E. Smith, Dea Nagy, Connie Cortez, Amit M. Algotar, Ubaradka Sathyanarayana, Raymond B. Nagle, Janice Riley, Carol Jones, Ryan Dittamore, Gary Pestano, Steven Yun
Publikováno v:
The Prostate. 73:1233-1240
BACKGROUND This study examines the combined effect of two common genetic alterations, ERG and PTEN, in prostate carcinoma progression. METHODS Prostate tissue from 90 patients having unilateral capsular penetrating lesions, and a contra-lateral organ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ad91b243260897a9bcb8856ea9f77b3
https://doi.org/10.1002/pros.22675
https://doi.org/10.1002/pros.22675
Autor:
Ubaradka G. Sathyanarayana, Ashley M Santa-Cruz, Karl Garsha, Theresa Y. MacDonald, Naoki Kitabayashi, Mark A. Rubin, Francesca Demichelis, Gary Pestano, Christopher J. LaFargue, Ashutosh K. Tewari, Dea Nagy, Jerry W. Kosmeder, Janice Riley, Chol S Yun, Maria A. Svensson, Dorothee Pflueger
Publikováno v:
Laboratory Investigation; a Journal of Technical Methods and Pathology
Prostate cancer is a clinically heterogeneous and multifocal disease. More than 80% of patients with prostate cancer harbor multiple geographically discrete cancer foci at the time of diagnosis. Emerging data suggest that these foci are molecularly d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f62e8b592a768b8d228b1dc001334ea
http://europepmc.org/articles/PMC3130188
http://europepmc.org/articles/PMC3130188
Autor:
Dea Nagy, Michael Otter, Esteban Roberts, Gary Pestano, Franklin Ventura, Ray B. Nagle, Michael Barnes, Karl Garsha
Publikováno v:
SPIE Proceedings.
Optical imaging techniques are being developed that promise to increase the information content related to specific molecular reporters. Such modalities do not produce contrast in the structural context of the surrounding tissue, making it difficult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0a2fbaff4ac2a5e0460cc7d3fb6dd94
https://doi.org/10.1117/12.2079872
https://doi.org/10.1117/12.2079872
Autor:
Dea Nagy, Glenn Pierce, Joseph A. Vargas, Tongyao Liu, Ciaran Scallan, Jurg M. Sommer, Haiyan Jiang, Sharmila Vijay, Federico Mingozzi, Linda B. Couto, Shangzhen Zhou, Katherine A. High, Susannah Patarroyo-White
Publikováno v:
Blood. 108:3321-3328
In a clinical study of recombinant adeno-associated virus-2 expressing human factor IX (AAV2-FIX), we detected 2 impediments to long-term gene transfer. First, preexisting anti-AAV neutralizing antibodies (NABs) prevent vector from reaching the targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a93d8959b01bd8bcfa3db9d312ee50
https://doi.org/10.1182/blood-2006-04-017913
https://doi.org/10.1182/blood-2006-04-017913
Autor:
Joseph Vargas, Dea Nagy, Haig H. Kazazian, Sharon K. Powell, Amy E. Parker, Tongyao Liu, Haifeng Chen, J. Fraser Wright, Linda B. Couto, Rita Sarkar, Susannah L. Patarroyo-White, Ciaran Scallan, Alan McClelland, Haiyan Jiang
Publikováno v:
Blood. 102:3919-3926
Using separate adeno-associated viral 2 (AAV2) vectors to deliver the heavy and light chains of factor VIII (FVIII) we have overcome the packaging limitations of AAV, achieving phenotypic correction of hemophilia A in mice. AAV vectors were construct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e4c5f821d5cda5e1657569180c7098f
https://doi.org/10.1182/blood-2003-01-0222
https://doi.org/10.1182/blood-2003-01-0222
Publikováno v:
Cytometry. 45:304-309
Background We have developed a method for selecting erythroblasts from blood, the first step toward identifying fetal cells in maternal blood for diagnostic purposes. Because the selection method results in a large number of positive cells, we needed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::947ca851f9b86ea86dc85f5541f3e419
https://doi.org/10.1002/1097-0320(20011201)45:4<304::aid-cyto10022>3.0.co
https://doi.org/10.1002/1097-0320(20011201)45:4<304::aid-cyto10022>3.0.co