Zobrazeno 1 - 10
of 48
pro vyhledávání: '"DeYing Gong"'
Autor:
Wei Xiao, Longyi Du, Linli Cai, Tiwei Miao, Bing Mao, Fuqiang Wen, Peter Gerard Gibson, Deying Gong, Yan Zeng, Mei Kang, Xinmiao Du, Junyan Qu, Yan Wang, Xuemei Liu, Ruizhi Feng, Juanjuan Fu, Peifang Wei
Publikováno v:
Chinese Medical Journal, Vol 135, Iss 13, Pp 1545-1554 (2022)
Abstract. Background:. Although existing mycological tests (bronchoalveolar lavage [BAL] galactomannan [GM], serum GM, serum (1,3)-β-D-glucan [BDG], and fungal culture) are widely used for diagnosing invasive pulmonary aspergillosis (IPA) in non-hem
Externí odkaz:
https://doaj.org/article/c675aad083474a2c9066acbe67834b9e
Publikováno v:
PeerJ, Vol 10, p e13995 (2022)
Background ET-26 hydrochloride (ET-26HCl) is a novel analogue of etomidate approved for clinical trials. However, all results from recent studies were accomplished in young adult animals. The objective of this study was to evaluate the efficacy and s
Externí odkaz:
https://doaj.org/article/64f31c82b9504b98864d22847019513b
Publikováno v:
PeerJ, Vol 10, p e13492 (2022)
Purpose We report on a novel ultra-short-acting etomidate analogue, E161111, which has the same primary metabolite as etomidate. Methods The metabolic rate of E161111 was determined in rat plasma and liver homogenate. Rats were infused for 30 or 60 m
Externí odkaz:
https://doaj.org/article/5c94fbd71f1140acb6b38cffd3c7fdd4
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: ET-26 hydrochloride (ET-26HCl), a class 1 new drug, was developed to reserve the advantages of etomidate with a mild adrenocortical inhibition.Purpose: this study was to evaluate the potential adverse effects on the cardiovascular system
Externí odkaz:
https://doaj.org/article/a6c61d15611f47dead86074903b19993
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Introduction: Previous studies demonstrated that 35 mM QX-OH/10 mM Levobupivacaine (LL-1), a fixed-dose combination, produced a long-acting effect in rat local anesthesia models. All preclinical pharmacodynamic results indicated that LL-1 had potenti
Externí odkaz:
https://doaj.org/article/a3edbaff57bf456da9911709ffeecd79
Autor:
Qinqin Yin, Yujun Zhang, Rong Lv, Deying Gong, Bowen Ke, Jun Yang, Lei Tang, Wensheng Zhang, Tao Zhu
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
QXOH, a QX314 derivative with longer duration and lesser local toxicity, is a novel local anesthetic in preclinical drug development. Previous studies demonstrated that bupivacaine can prolong the effects of QX314. So, we attempted to combine QXOH wi
Externí odkaz:
https://doaj.org/article/a29ae35e765e46bdafb84d3d88f4d18d
Publikováno v:
ACS Medicinal Chemistry Letters. 14:405-410
Autor:
Lei Tang, Feng Qin, Deying Gong, LiLi Pan, Changcui Zhou, Rui Ling, Wenxue Shen, Qin Fan, Wenhao Yi, Fengbo Wu, Xiaoai Wu, Weiyi Zhang, Jun Yang
Publikováno v:
Chemical Communications. 59:1653-1656
Nano systems self-assembled only by lidocaine salts exhibit unexpected unique behaviors in different local tissues based on their intermolecular interaction, and can achieve up to 7.8 h sensory block without excipient residue.
Autor:
Jing Liu, Weiwei Wu, Fei Peng, Deying Gong, Yi Kang, Yujun Zhang, Congyan Liu, Yuncheng Li, Guoyan Zhao, Feng Qiu, Wensheng Zhang
Publikováno v:
Theranostics; 2024, Vol. 14 Issue 6, p2637-2655, 19p
Autor:
Duo Qian, Qianqian Zhang, Cheng Zhou, YuJun Zhang, Hangxue Cao, Jin Liu, Qinqin Yin, Wensheng Zhang, Linghui Yang, Jun Yang, Bowen Ke, Deying Gong, Yi Kang, Tang Lei, Jing Fan
Publikováno v:
Regional Anesthesia & Pain Medicine. 45:412-418
Background and objectiveLong-acting nociceptive-selective regional anesthesia has remained an elusive clinical goal. We aspired to identify a novel compound that would produce nociceptive-selective regional anesthesia through the transient receptor p