Výsledky vyhledávání - "DeStefano JG"

Akademický článek

Three-dimensional microenvironment regulates gene expression, function, and tight junction dynamics of iPSC-derived blood-brain barrier microvessels.

Autor: Linville RM; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA. raleigh@jhu.edu.; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA. raleigh@jhu.edu., Sklar MB; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA., Grifno GN; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA.; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA., Nerenberg RF; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA.; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA., Zhou J; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA.; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA., Ye R; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA., DeStefano JG; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA.; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, USA., Guo Z; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA., Jha R; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA.; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA., Jamieson JJ; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA.; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA., Zhao N; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA., Searson PC; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA. searson@jhu.edu.; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA. searson@jhu.edu.; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, USA. searson@jhu.edu.

Publikováno v: Fluids and barriers of the CNS [Fluids Barriers CNS] 2022 Nov 05; Vol. 19 (1), pp. 87. Date of Electronic Publication: 2022 Nov 05.

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Reversible blood-brain barrier opening utilizing the membrane active peptide melittin in vitro and in vivo.

Autor: Linville RM; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA., Komin A; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, USA., Lan X; Department of Diagnostic Radiology & Nuclear Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., DeStefano JG; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, USA., Chu C; Department of Diagnostic Radiology & Nuclear Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Liu G; Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Walczak P; Department of Diagnostic Radiology & Nuclear Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Hristova K; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, USA., Searson PC; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, USA. Electronic address: searson@jhu.edu.

Publikováno v: Biomaterials [Biomaterials] 2021 Aug; Vol. 275, pp. 120942. Date of Electronic Publication: 2021 Jun 10.

Zobrazit plný text záznamu

Akademický článek

Long-Term Cryopreservation Preserves Blood-Brain Barrier Phenotype of iPSC-Derived Brain Microvascular Endothelial Cells and Three-Dimensional Microvessels.

Autor: Linville RM; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, Maryland 21218, United States.; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 21218, United States., DeStefano JG; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, Maryland 21218, United States.; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, Maryland 21218, United States., Nerenberg RF; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, Maryland 21218, United States.; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 21218, United States., Grifno GN; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, Maryland 21218, United States.; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 21218, United States., Ye R; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, Maryland 21218, United States., Gallagher E; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, Maryland 21218, United States.; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, Maryland 21218, United States., Searson PC; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, Maryland 21218, United States.; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 21218, United States.; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, Maryland 21218, United States.

Publikováno v: Molecular pharmaceutics [Mol Pharm] 2020 Sep 08; Vol. 17 (9), pp. 3425-3434. Date of Electronic Publication: 2020 Aug 13.

Zobrazit plný text záznamu

Akademický článek

Modeling hyperosmotic blood-brain barrier opening within human tissue-engineered in vitro brain microvessels.

Autor: Linville RM; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA.; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA., DeStefano JG; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA.; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, USA., Sklar MB; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA., Chu C; Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Walczak P; Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Searson PC; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA.; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, USA.

Publikováno v: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2020 Jul; Vol. 40 (7), pp. 1517-1532. Date of Electronic Publication: 2019 Aug 08.

Zobrazit plný text záznamu

Akademický článek

Cerebrovascular plasticity: Processes that lead to changes in the architecture of brain microvessels.

Autor: Bogorad MI; 1 Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA.; 2 Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, USA., DeStefano JG; 1 Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA.; 2 Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, USA., Linville RM; 1 Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA.; 3 Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA., Wong AD; 1 Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA.; 2 Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, USA., Searson PC; 1 Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA.; 2 Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, USA.; 3 Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.

Publikováno v: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2019 Aug; Vol. 39 (8), pp. 1413-1432. Date of Electronic Publication: 2019 Jun 17.

Zobrazit plný text záznamu

Akademický článek

Human iPSC-derived blood-brain barrier microvessels: validation of barrier function and endothelial cell behavior.

Autor: Linville RM; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, United States; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, United States., DeStefano JG; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, United States; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, United States., Sklar MB; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, United States., Xu Z; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, United States; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, United States., Farrell AM; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, United States; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, United States., Bogorad MI; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, United States; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, United States., Chu C; Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, United States., Walczak P; Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, United States., Cheng L; Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, United States., Mahairaki V; Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, United States; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, United States., Whartenby KA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, United States., Calabresi PA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, United States., Searson PC; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, United States; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, United States. Electronic address: searson@jhu.edu.

Publikováno v: Biomaterials [Biomaterials] 2019 Jan; Vol. 190-191, pp. 24-37. Date of Electronic Publication: 2018 Oct 25.

Zobrazit plný text záznamu

Akademický článek

Benchmarking in vitro tissue-engineered blood-brain barrier models.

Autor: DeStefano JG; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA.; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, USA., Jamieson JJ; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA.; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA., Linville RM; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA.; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Searson PC; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA. searson@jhu.edu.; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, USA. searson@jhu.edu.; 120 Croft Hall, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD, 21218, USA. searson@jhu.edu.

Publikováno v: Fluids and barriers of the CNS [Fluids Barriers CNS] 2018 Dec 04; Vol. 15 (1), pp. 32. Date of Electronic Publication: 2018 Dec 04.

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Effect of shear stress on iPSC-derived human brain microvascular endothelial cells (dhBMECs).

Autor: DeStefano JG; Institute for Nanobiotechnology, Johns Hopkins University, 100 Croft Hall, 3400 North Charles Street, Baltimore, MD, 21218, USA.; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA., Xu ZS; Institute for Nanobiotechnology, Johns Hopkins University, 100 Croft Hall, 3400 North Charles Street, Baltimore, MD, 21218, USA.; Department of Biomedical Engineering, Johns Hopkins University, 720 Rutland Avenue, Baltimore, MD, 21205, USA., Williams AJ; Institute for Nanobiotechnology, Johns Hopkins University, 100 Croft Hall, 3400 North Charles Street, Baltimore, MD, 21218, USA., Yimam N; Institute for Nanobiotechnology, Johns Hopkins University, 100 Croft Hall, 3400 North Charles Street, Baltimore, MD, 21218, USA., Searson PC; Institute for Nanobiotechnology, Johns Hopkins University, 100 Croft Hall, 3400 North Charles Street, Baltimore, MD, 21218, USA. searson@jhu.edu.; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA. searson@jhu.edu.

Publikováno v: Fluids and barriers of the CNS [Fluids Barriers CNS] 2017 Aug 04; Vol. 14 (1), pp. 20. Date of Electronic Publication: 2017 Aug 04.

Zobrazit plný text záznamu

Akademický článek

Real-time quantification of endothelial response to shear stress and vascular modulators.

Autor: DeStefano JG; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, Maryland 21218, USA. adwong@jhu.edu., Williams A, Wnorowski A, Yimam N, Searson PC, Wong AD

Publikováno v: Integrative biology : quantitative biosciences from nano to macro [Integr Biol (Camb)] 2017 Apr 18; Vol. 9 (4), pp. 362-374.

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání