Zobrazeno 1 - 6
of 6
pro vyhledávání: '"DeMasi, DK"'
Autor:
Burt, T, MacLeod, D, Lee, K, Santoro, A, DeMasi, DK, Hawk, T, Feinglos, M, Rowland, M, Noveck, RJ
Publikováno v:
Burt, T, MacLeod, D C, Lee, K, Santoro, A, Demasi, D K, Hawk, T, Feinglos, M, Rowland, M & Noveck, R J 2017, ' Intra-Target Microdosing-A Novel Drug Development Approach : Proof of Concept, Safety, and Feasibility Study in Humans ', Clinical and Translational Science . https://doi.org/10.1111/cts.12477
Clinical and Translational Science
Clinical and Translational Science
Intra-target microdosing (ITM) is a novel drug development approach aimed at increasing the efficiency of first-in-human (FIH) testing of new molecular entities (NMEs). ITM combines intra-target drug delivery and "microdosing," the subpharmacological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fb9bdacdfdf553dd1b41f0974baa6baf
https://doi.org/10.1111/cts.12477
https://doi.org/10.1111/cts.12477
Autor:
Burt, T, MacLeod, D, Lee, K, Santoro, A, DeMasi, DK, Hawk, T, Feinglos, M, Rowland, M, Noveck, RJ
Publikováno v:
CTS: Clinical & Translational Science; Sep2017, Vol. 10 Issue 5, p351-359, 9p
Hypercapnia is essential to reduce the cerebral oxidative metabolism during extreme apnea in humans.
Autor:
Bain AR; 1 Centre for Heart Lung and Vascular Health, University of British Columbia, Kelowna, BC, Canada., Ainslie PN; 1 Centre for Heart Lung and Vascular Health, University of British Columbia, Kelowna, BC, Canada., Barak OF; 2 School of Medicine, University of Split, Split, Croatia., Hoiland RL; 3 Faculty of Medicine, University of Novi Sad, Serbia., Drvis I; 4 School of Kinesiology, University of Zagreb, Zagreb, Croatia., Mijacika T; 2 School of Medicine, University of Split, Split, Croatia., Bailey DM; 5 Faculty of Life Sciences and Education, University of South Wales, Glamorgan, UK., Santoro A; 6 Duke University Medical Center, Durham, NC, USA., DeMasi DK; 6 Duke University Medical Center, Durham, NC, USA., Dujic Z; 2 School of Medicine, University of Split, Split, Croatia., MacLeod DB; 6 Duke University Medical Center, Durham, NC, USA.
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2017 Sep; Vol. 37 (9), pp. 3231-3242. Date of Electronic Publication: 2017 Jan 10.
Autor:
Burt T; Burt Consultancy, LLC, Durham, North Carolina, USA., MacLeod D; Department of Anesthesiology, Duke University, Durham, North Carolina, USA., Lee K; MI, CCC-TDI, OPS, SV, Siemens Medical Solutions USA, Inc., Knoxville, Tennessee, USA., Santoro A; Department of Anesthesiology, Duke University, Durham, North Carolina, USA., DeMasi DK; Wake Forest School of Medicine, Winston Salem, North Carolina, USA., Hawk T; Department of Radiology, Duke University, Durham, North Carolina, USA., Feinglos M; Department of Endocrinology, Duke University, Durham, North Carolina, USA., Rowland M; Manchester Pharmacy School, University of Manchester, Manchester, UK., Noveck RJ; Duke Clinical Research Institute, Duke University, Durham, North Carolina, USA.
Publikováno v:
Clinical and translational science [Clin Transl Sci] 2017 Sep; Vol. 10 (5), pp. 351-359. Date of Electronic Publication: 2017 Jul 08.
Autor:
Bain AR; Centre for Heart Lung and Vascular Health, University of British Columbia, Kelowna, BC, Canada; Integrative Vascular Biology Laboratory, Colorado University, Boulder, United States. Electronic address: Anthony.bain@colorado.edu., Barak OF; School of Medicine, University of Split, Split, Croatia; Faculty of Medicine, University of Novi Sad, Serbia., Hoiland RL; Centre for Heart Lung and Vascular Health, University of British Columbia, Kelowna, BC, Canada., Drvis I; Faculty of Kinesiology, University of Zagreb, Zagreb, Croatia., Bailey DM; Faculty of Life Sciences and Education, University of South Wales, Glamorgan, United Kingdom., Dujic Z; School of Medicine, University of Split, Split, Croatia., Mijacika T; School of Medicine, University of Split, Split, Croatia., Santoro A; Duke University Medical Center, Durham, NC, United States., DeMasi DK; Duke University Medical Center, Durham, NC, United States., MacLeod DB; Duke University Medical Center, Durham, NC, United States., Ainslie PN; Centre for Heart Lung and Vascular Health, University of British Columbia, Kelowna, BC, Canada.
Publikováno v:
Respiratory physiology & neurobiology [Respir Physiol Neurobiol] 2017 Aug; Vol. 242, pp. 8-11. Date of Electronic Publication: 2017 Mar 11.
Autor:
Bailey DM; 1 Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales , Glamorgan, United Kingdom .; 2 Faculty of Medicine, University of British Columbia-Okanagan , Kelowna, British Columbia, Canada ., Willie CK; 3 Centre for Heart, Lung, and Vascular Health, School of Health and Exercise Sciences, University of British Columbia-Okanagan , Kelowna, British Columbia, Canada ., Hoiland RL; 3 Centre for Heart, Lung, and Vascular Health, School of Health and Exercise Sciences, University of British Columbia-Okanagan , Kelowna, British Columbia, Canada ., Bain AR; 3 Centre for Heart, Lung, and Vascular Health, School of Health and Exercise Sciences, University of British Columbia-Okanagan , Kelowna, British Columbia, Canada ., MacLeod DB; 4 Human Pharmacology and Physiology Laboratory, Department of Anesthesiology, Duke University Medical Center , Durham, North Carolina., Santoro MA; 4 Human Pharmacology and Physiology Laboratory, Department of Anesthesiology, Duke University Medical Center , Durham, North Carolina., DeMasi DK; 4 Human Pharmacology and Physiology Laboratory, Department of Anesthesiology, Duke University Medical Center , Durham, North Carolina., Andrijanic A; 5 School of Management, Libertas International University , Zagreb, Croatia ., Mijacika T; 6 School of Medicine, University of Split , Split, Croatia ., Barak OF; 6 School of Medicine, University of Split , Split, Croatia .; 7 Faculty of Medicine, University of Novi Sad , Novi Sad, Serbia ., Dujic Z; 6 School of Medicine, University of Split , Split, Croatia ., Ainslie PN; 1 Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales , Glamorgan, United Kingdom .; 3 Centre for Heart, Lung, and Vascular Health, School of Health and Exercise Sciences, University of British Columbia-Okanagan , Kelowna, British Columbia, Canada .
Publikováno v:
High altitude medicine & biology [High Alt Med Biol] 2017 Mar; Vol. 18 (1), pp. 73-79. Date of Electronic Publication: 2016 Dec 21.