Evolution of mitral regurgitation in patients with heart failure referred to a tertiary heart failure clinic

Autor: Lotte E. deGroot – de Laat, Jessy Huizer, Mattie Lenzen, Ernest Spitzer, Ben Ren, Marcel L. Geleijnse, Kadir Caliskan

Publikováno v: ESC Heart Failure, Vol 6, Iss 5, Pp 936-943 (2019)

Abstract Aims Significant mitral regurgitation (MR) is an important predictor for all‐cause mortality and heart failure (HF) hospitalizations independent of left ventricular ejection fraction (LVEF). The aims of this study were to investigate (i) i

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The Alginate Immobilization of Metabolic Enzymes Platform Retrofits an Estrogen Receptor Transactivation Assay With Metabolic Competence.

Autor: Deisenroth C; Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711., DeGroot DE; Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711., Zurlinden T; Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711., Eicher A; Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711., McCord J; Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711., Lee MY; Safety and Environmental Assurance Centre, Unilever, Colworth Science, Park, Bedford, Sharnbrook MK44 1LQ, UK., Carmichael P; Safety and Environmental Assurance Centre, Unilever, Colworth Science, Park, Bedford, Sharnbrook MK44 1LQ, UK., Thomas RS; Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711.

Publikováno v: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2020 Dec 01; Vol. 178 (2), pp. 281-301.

Naturally occurring marine brominated indoles are aryl hydrocarbon receptor ligands/agonists.

Autor: DeGroot DE; †Department of Environmental Toxicology, University of California, Davis, California 95616, United States., Franks DG; ‡Department of Biology and the Woods Hole Center for Oceans and Human Health, Woods Hole Oceanographic Institution, Woods Hole, Massachusetts 02543, United States., Higa T; §Department of Chemistry, Biology, and Marine Sciences, University of the Ryukyus, Nishihara, Okinawa 903-0213, Japan., Tanaka J; §Department of Chemistry, Biology, and Marine Sciences, University of the Ryukyus, Nishihara, Okinawa 903-0213, Japan., Hahn ME; ‡Department of Biology and the Woods Hole Center for Oceans and Human Health, Woods Hole Oceanographic Institution, Woods Hole, Massachusetts 02543, United States., Denison MS; †Department of Environmental Toxicology, University of California, Davis, California 95616, United States.

Publikováno v: Chemical research in toxicology [Chem Res Toxicol] 2015 Jun 15; Vol. 28 (6), pp. 1176-85. Date of Electronic Publication: 2015 Jun 02.

Lack of ligand-selective binding of the aryl hydrocarbon receptor to putative DNA binding sites regulating expression of Bax and paraoxonase 1 genes.

Autor: DeGroot DE; Department of Environmental Toxicology, University of California, Davis, CA 95616, United States., Hayashi A; Department of Environmental Toxicology, University of California, Davis, CA 95616, United States., Denison MS; Department of Environmental Toxicology, University of California, Davis, CA 95616, United States. Electronic address: msdenison@ucdavis.edu.

Publikováno v: Archives of biochemistry and biophysics [Arch Biochem Biophys] 2014 Jan 01; Vol. 541, pp. 13-20. Date of Electronic Publication: 2013 Nov 04.