Výsledky vyhledávání

Akademický článek

PRC1 suppresses a female gene regulatory network to ensure testicular differentiation

Autor: So Maezawa, Masashi Yukawa, Kazuteru Hasegawa, Ryo Sugiyama, Mizuho Iizuka, Mengwen Hu, Akihiko Sakashita, Miguel Vidal, Haruhiko Koseki, Artem Barski, Tony DeFalco, Satoshi H. Namekawa

Publikováno v: Cell Death and Disease, Vol 14, Iss 8, Pp 1-12 (2023)

Abstract Gonadal sex determination and differentiation are controlled by somatic support cells of testes (Sertoli cells) and ovaries (granulosa cells). In testes, the epigenetic mechanism that maintains chromatin states responsible for suppressing fe

Externí odkaz: https://doaj.org/article/aa478729c1c142cc857ac4f13d7a9ee7

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Akademický článek

Steroid hormone signaling: multifaceted support of testicular function

Autor: Satoko Matsuyama, Tony DeFalco

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 11 (2024)

Embryonic development and adult physiology are dependent on the action of steroid hormones. In particular, the reproductive system is reliant on hormonal signaling to promote gonadal function and to ensure fertility. Here we will describe hormone rec

Externí odkaz: https://doaj.org/article/21889810a1a442289404f76ae1a20c71

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Akademický článek

Unprecedented distribution data for Joshua trees (Yucca brevifolia and Y. jaegeriana) reveal contemporary climate associations of a Mojave Desert icon

Autor: Todd C. Esque, Daniel F. Shryock, Gabrielle A. Berry, Felicia C. Chen, Lesley A. DeFalco, Sabrina M. Lewicki, Brent L. Cunningham, Eddie J. Gaylord, Caitlan S. Poage, Gretchen E. Gantz, Ross A. Van Gaalen, Ben O. Gottsacker, Amanda M. McDonald, Jeremy B. Yoder, Christopher I. Smith, Kenneth E. Nussear

Publikováno v: Frontiers in Ecology and Evolution, Vol 11 (2023)

IntroductionForecasting range shifts in response to climate change requires accurate species distribution models (SDMs), particularly at the margins of species' ranges. However, most studies producing SDMs rely on sparse species occurrence datasets f

Externí odkaz: https://doaj.org/article/c0e4e90742e5443b810c3a43bfb0d834

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Akademický článek

Testicular macrophages are recruited during a narrow fetal time window and promote organ-specific developmental functions

Autor: Xiaowei Gu, Anna Heinrich, Shu-Yun Li, Tony DeFalco

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)

How testis resident macrophages develop and influence tissue function is not fully understood. Here the authors use mouse lineage tracing methods to document the haematopoietic source, development and recruitment of early testicular macrophages, supp

Externí odkaz: https://doaj.org/article/730fd7a4027c4576908884a85788b2c3

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