Rank Suggestion in Non-negative Matrix Factorization: Residual Sensitivity to Initial Conditions (RSIC)

Autor: Tunnell, Marc A., DeBruine, Zachary J., Carrier, Erin

Determining the appropriate rank in Non-negative Matrix Factorization (NMF) is a critical challenge that often requires extensive parameter tuning and domain-specific knowledge. Traditional methods for rank determination focus on identifying a single

Externí odkaz: http://arxiv.org/abs/2410.14838

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EZH2-driven immune evasion defines high-risk pediatric AML with t(16;21) FUS::ERG gene fusion.

Autor: Buteyn NJ; Department of Epigenetics, Van Andel Research Institute, Grand Rapids, MI., Burke CG; Department of Epigenetics, Van Andel Research Institute, Grand Rapids, MI., Sartori VJ; Department of Epigenetics, Van Andel Research Institute, Grand Rapids, MI., Deering-Gardner E; Department of Epigenetics, Van Andel Research Institute, Grand Rapids, MI., DeBruine ZJ; Department of Epigenetics, Van Andel Research Institute, Grand Rapids, MI., Kamarudin D; Department of Epigenetics, Van Andel Research Institute, Grand Rapids, MI., Chandler DP; Department of Epigenetics, Van Andel Research Institute, Grand Rapids, MI., Monovich AC; Department of Pathology, University of Michigan, Ann Arbor, MI., Perez MW; Department of Genome Sciences, University of Washington, Seattle, WA., Yi JS; Department of Pediatrics, Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, TX., Ries RE; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA., Alonzo TA; Children's Oncology Group, Monrovia, CA.; Department of Translational Genomics, University of Southern California, Los Angeles, CA., Ryan RJ; Department of Pathology, University of Michigan, Ann Arbor, MI., Meshinchi S; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.; Children's Oncology Group, Monrovia, CA.; Department of Pediatrics, University of Washington, Seattle, WA., Triche TJ Jr; Department of Epigenetics, Van Andel Research Institute, Grand Rapids, MI.; Department of Translational Genomics, University of Southern California, Los Angeles, CA.; Department of Pediatrics, College of Human Medicine, Michigan State University, East Lansing, MI.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jun 25. Date of Electronic Publication: 2024 Jun 25.