Zobrazeno 1 - 10
of 38
pro vyhledávání: '"DeAnna Baker"'
Autor:
DeAnna Baker Frost, Alisa Savchenko, Naoko Takamura, Bethany Wolf, Roselyn Fierkens, Kimberly King, Carol Feghali-Bostwick
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7227 (2024)
Systemic sclerosis (SSc) is characterized by dermal fibrosis with a female predominance, suggesting a hormonal influence. Patients with SSc have elevated interleukin (IL)-6 levels, and post-menopausal women and older men also have high estradiol (E2)
Externí odkaz:
https://doaj.org/article/a770958b88164d5c897596ae80c0fd28
Autor:
Peter C. Allen, Sarah Smith, Robert C. Wilson, Jena R. Wirth, Nathan H. Wilson, DeAnna Baker Frost, Jonathan Flume, Gary S. Gilkeson, Melissa A. Cunningham, Carl D. Langefeld, Devin M. Absher, Paula S. Ramos
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-15 (2023)
Abstract Background Systemic sclerosis (SSc) is a multisystem autoimmune disorder that has an unclear etiology and disproportionately affects women and African Americans. Despite this, African Americans are dramatically underrepresented in SSc resear
Externí odkaz:
https://doaj.org/article/9bde2b02efb54851af0a150dc4de6d0c
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 182 (2024)
In the skin, estradiol (E2) promotes profibrotic and proinflammatory cytokines, contributing to extracellular matrix (ECM) deposition. However, the magnitude of the response differs. Using the human skin organ culture model, we evaluated donor charac
Externí odkaz:
https://doaj.org/article/54b005e603cb4a059750b186aba1f968
Autor:
DeAnna Baker Frost, Alisa Savchenko, Adeyemi Ogunleye, Milton Armstrong, Carol Feghali-Bostwick
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-10 (2021)
Abstract Background Both TGFβ and estradiol (E2), a form of estrogen, are pro-fibrotic in the skin. In the connective tissue disease, systemic sclerosis (SSc), both TGFβ and E2 are likely pathogenic. Yet the regulation of TGFβ in E2-induced dermal
Externí odkaz:
https://doaj.org/article/9319fbf2e1974e6ab9cdb5abb7e6fcb0
Autor:
DeAnna Baker Frost, Bethany Wolf, Christine Peoples, Jessica Fike, Katherine Silver, Maureen Laffoon, Thomas A. Medsger, Carol Feghali-Bostwick
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-9 (2019)
Abstract Background Systemic sclerosis (SSc) is a female-predominant disease, characterized by excessive extracellular matrix deposition (ECM) with dermal and internal organ fibrosis. Considering the sex-based disparity in disease incidence, estradio
Externí odkaz:
https://doaj.org/article/4262bd3c1eb24f33ab7cea735356d132
Publikováno v:
Beyond Rheumatology, Vol 3 (2021)
Systemic lupus erythematosus (SLE) is a chronic autoimmune and inflammatory disease with multisystem consequences. Pseudo-pseudo Meigs’ syndrome (PPMS), or Tjalma syndrome, is a newly recognized manifestation of SLE that is characterized by increas
Externí odkaz:
https://doaj.org/article/33e6d9d301004fb1a2c85a5f64d8ad02
Autor:
DeAnna Baker Frost, Bethany Wolf, Christine Peoples, Jessica Fike, Katherine Silver, Maureen Laffoon, Thomas A. Medsger, Carol Feghali-Bostwick
Publikováno v:
Journal of Clinical and Translational Science, Vol 3, Pp 104-105 (2019)
OBJECTIVES/SPECIFIC AIMS: Our objective was to examine serum E2 levels in dcSSc males in relation to disease characteristics (i.e autoanitbody profile and internal organ involvement) and its impact on survival. METHODS/STUDY POPULATION: We measured s
Externí odkaz:
https://doaj.org/article/e187a1b1d8b3473bb43fc49117c282eb
Akademický článek
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Autor:
Elizabeth R Volkmann, Donald P Tashkin, Richard Silver, Carol Feghali Bostwick, Shervin Assassi, DeAnna Baker Frost, Mei Leng, Holly Wilhalme, Grace Hyun Kim, Jonathan Goldin, Michael D Roth
Publikováno v:
The Lancet Rheumatology. 4:e668-e678
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1ee9f851569b33c23dad22dcce441b4
https://doi.org/10.1016/s2665-9913(22)00193-x
https://doi.org/10.1016/s2665-9913(22)00193-x
Akademický článek
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