Zobrazeno 1 - 10 of 97 pro vyhledávání: '"De-En Hu"'
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Akademický článek
18F-C2Am: a targeted imaging agent for detecting tumor cell death in vivo using positron emission tomography
Autor: Flaviu Bulat, Friederike Hesse, De-En Hu, Susana Ros, Connor Willminton-Holmes, Bangwen Xie, Bala Attili, Dmitry Soloviev, Franklin Aigbirhio, Finian. J. Leeper, Kevin M. Brindle, André A. Neves
Publikováno v: EJNMMI Research, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Introduction Trialing novel cancer therapies in the clinic would benefit from imaging agents that can detect early evidence of treatment response. The timing, extent and distribution of cell death in tumors following treatment can give an in
Externí odkaz: https://doaj.org/article/e21d4f55168b4903adafd4356cd7f69c
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2
Akademický článek
A Comparison between Radiolabeled Fluorodeoxyglucose Uptake and Hyperpolarized 13C-Labeled Pyruvate Utilization as Methods for Detecting Tumor Response to Treatment
Autor: Timothy H. Witney, Mikko I. Kettunen, Samuel E. Day, De-en Hu, Andre A. Neves, Ferdia A. Gallagher, Sandra M. Fulton, Kevin M. Brindle
Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 6, Pp 574-582 (2009)
Detection of early tumor responses to treatment can give an indication of clinical outcome. Positron emission tomography measurements of the uptake of the glucose analog, [18F] 2-fluoro-2-deoxy-d-glucose (FDG), have demonstrated their potential for d
Externí odkaz: https://doaj.org/article/766ec00b626d435e96e28cbdaba92219
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5
Video - from Optoacoustic Detection of Early Therapy-Induced Tumor Cell Death Using a Targeted Imaging Agent
Autor: Kevin M. Brindle, Robert W. Wilkinson, Sarah E. Bohndiek, Richard C.A. Sainson, David Tice, Stefanie R. Mullins, Sarah McGuire, De-En Hu, Susana Ros, André A. Neves, Michal R. Tomaszewski, Bangwen Xie
Supplementary videos. Representative reconstructed 3D rendering of a Colo205 tumor 3 h after injection of 0.2 µmole/kg of C2Am-750. Signals from C2Am-750, oxygenated hemoglobin (HbO2), deoxygenated hemoglobin (Hb) are shown in green, red and blue re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b293660af54350dae220ee09a01c2b
https://doi.org/10.1158/1078-0432.22463276.v1
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Data from Optoacoustic Detection of Early Therapy-Induced Tumor Cell Death Using a Targeted Imaging Agent
Autor: Kevin M. Brindle, Robert W. Wilkinson, Sarah E. Bohndiek, Richard C.A. Sainson, David Tice, Stefanie R. Mullins, Sarah McGuire, De-En Hu, Susana Ros, André A. Neves, Michal R. Tomaszewski, Bangwen Xie
Purpose: The development of new treatments and their deployment in the clinic may be assisted by imaging methods that allow an early assessment of treatment response in individual patients. The C2A domain of Synaptotagmin-I (C2Am), which binds to the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03869d7447f0a5db80e579a7bc991957
https://doi.org/10.1158/1078-0432.c.6525359.v1
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Data from Metabolic Imaging Detects Low Levels of Glycolytic Activity That Vary with Levels of c-Myc Expression in Patient-Derived Xenograft Models of Glioblastoma
Autor: Kevin M. Brindle, Colin Watts, Jyotsna Rao, Felix Kreis, Tom Booth, De-en Hu, Susana Ros, Alan J. Wright, Richard Mair
13C MRI of hyperpolarized [1-13C]pyruvate metabolism has been used in oncology to detect disease, investigate disease progression, and monitor response to treatment with a view to guiding treatment in individual patients. This technique has translate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e834e7c377e84635785da6ebd3b30ef
https://doi.org/10.1158/0008-5472.c.6510314.v1
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