Zobrazeno 1 - 10
of 103
pro vyhledávání: '"De novo DNA methylation"'
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
RNA-directed DNA methylation (RdDM) is driven by small RNAs (sRNAs) complementary to the nascent transcript of RNA polymerase V (Pol V). sRNAs associated with ARGONAUTE (AGO) proteins are tethered to Pol V mainly by the AGO-hook domain of its subunit
Externí odkaz:
https://doaj.org/article/378e549b1329430ba7dfcaa8fddba0fa
Akademický článek
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Autor:
Tomonori KAMEDA, Hideyuki NAKASHIMA, Takumi TAKIZAWA, Fumihito MIURA, Takashi ITO, Kinichi NAKASHIMA, Takuya IMAMURA
Publikováno v:
The Journal of Reproduction and Development, Vol 67, Iss 6, Pp 369-379 (2021)
Post-mitotic neurons do exhibit DNA methylation changes, contrary to the longstanding belief that the epigenetic pattern in terminally differentiated cells is essentially unchanged. While the mechanism and physiological significance of DNA demethylat
Externí odkaz:
https://doaj.org/article/05bf0e296b3d45e495e3c006aa04c7f3
Akademický článek
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Autor:
Schöpp, Theresa
The PIWI-interacting RNA (piRNA) pathway instructs DNA methylation of young active transposable elements (TEs) in the male germline via the PIWI protein MIWI2. In the proposed model MIWI2 is recruited to transcriptionally active TE loci via base pair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______463::c6941319e89c4f2a08a21de1467ccda0
https://hdl.handle.net/1842/39688
https://hdl.handle.net/1842/39688
Autor:
Jesús León-Ruiz, Annie Espinal-Centeno, Ikram Blilou, Ben Scheres, Mario Arteaga-Vázquez, Alfredo Cruz-Ramírez
Publikováno v:
Planta 257 (2023) 6
Planta, 257(6)
Planta, 257(6)
Main Conclusion: Our study presents evidence for a novel mechanism for RBR function in transcriptional gene silencing by interacting with key players of the RdDM pathway in Arabidopsis and several plant clades. Abstract: Transposable elements and oth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9df21295f0ba3aac525450b611b6995
https://research.wur.nl/en/publications/retinoblastoma-related-interactions-with-key-factors-of-the-rna-d
https://research.wur.nl/en/publications/retinoblastoma-related-interactions-with-key-factors-of-the-rna-d
Autor:
KAMEDA, Tomonori, NAKASHIMA, Hideyuki, TAKIZAWA, Takumi, MIURA, Fumihito, ITO, Takashi, NAKASHIMA, Kinichi, IMAMURA, Takuya
Publikováno v:
The Journal of Reproduction and Development
Post-mitotic neurons do exhibit DNA methylation changes, contrary to the longstanding belief that the epigenetic pattern in terminally differentiated cells is essentially unchanged. While the mechanism and physiological significance of DNA demethylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::baf1843415712eaf1de0e370642fc2e6
http://europepmc.org/articles/PMC8668374
http://europepmc.org/articles/PMC8668374
Akademický článek
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Autor:
Meng Amy Li, Paulo P Amaral, Priscilla Cheung, Jan H Bergmann, Masaki Kinoshita, Tüzer Kalkan, Meryem Ralser, Sam Robson, Ferdinand von Meyenn, Maike Paramor, Fengtang Yang, Caifu Chen, Jennifer Nichols, David L Spector, Tony Kouzarides, Lin He, Austin Smith
Publikováno v:
eLife, Vol 6 (2017)
Execution of pluripotency requires progression from the naïve status represented by mouse embryonic stem cells (ESCs) to a state capacitated for lineage specification. This transition is coordinated at multiple levels. Non-coding RNAs may contribute
Externí odkaz:
https://doaj.org/article/10bac2ec83364a588083e62380429289
Autor:
Zhongliang Jiang, Yanhao Lai, Jill M. Beaver, Pawlos S. Tsegay, Ming-Lang Zhao, Julie K. Horton, Marco Zamora, Hayley L. Rein, Frank Miralles, Mohammad Shaver, Joshua D. Hutcheson, Irina Agoulnik, Samuel H. Wilson, Yuan Liu
Publikováno v:
Cells, Vol 9, Iss 1, p 225 (2020)
DNA damage and base excision repair (BER) are actively involved in the modulation of DNA methylation and demethylation. However, the underlying molecular mechanisms remain unclear. In this study, we seek to understand the mechanisms by exploring the
Externí odkaz:
https://doaj.org/article/788c11cb8b9c443193a8998431ba13e9