Zobrazeno 1 - 10
of 664
pro vyhledávání: '"De differentiation"'
Autor:
Mara Mancini, Simone Sergio, Angela Cappello, Timea Farkas, Francesca Bernassola, Claudia Scarponi, Cristina Albanesi, Gerry Melino, Eleonora Candi
Publikováno v:
Biology Direct, Vol 18, Iss 1, Pp 1-9 (2023)
Abstract The uc.291 transcript controls keratinocytes differentiation by physical interaction with ACTL6A and subsequent induction of transcription of the genes belonging to the epidermal differentiation complex (EDC). Uc.291 is also implicated in th
Externí odkaz:
https://doaj.org/article/0db348d7f0bb4cd5bf642122460f0b2c
Autor:
Yuwei Zhang, Lina Sui, Qian Du, Leena Haataja, Yishu Yin, Ryan Viola, Shuangyi Xu, Christian Ulrik Nielsson, Rudolph L. Leibel, Fabrizio Barbetti, Peter Arvan, Dieter Egli
Publikováno v:
Molecular Metabolism, Vol 80, Iss , Pp 101879- (2024)
Objective: Heterozygous coding sequence mutations of the INS gene are a cause of permanent neonatal diabetes (PNDM), requiring insulin therapy similar to T1D. While the negative effects on insulin processing and secretion are known, how dominant insu
Externí odkaz:
https://doaj.org/article/8fce543b22c7434f8a6ea4fc5678ee55
Autor:
Zhe Cha, Zhiyuan Yin, Luodan A, Lingling Ge, Junling Yang, Xiaona Huang, Hui Gao, Xia Chen, Zhou Feng, Lingyue Mo, Juncai He, Shuang Zhu, Maoru Zhao, Zui Tao, Zhanjun Gu, Haiwei Xu
Publikováno v:
Redox Biology, Vol 67, Iss , Pp 102911- (2023)
Excessive light exposure can damage photoreceptors and lead to blindness. Oxidative stress serves a key role in photo-induced retinal damage. Free radical scavengers have been proven to protect against photo-damaged retinal degeneration. Fullerol, a
Externí odkaz:
https://doaj.org/article/63e5991c586b4914bcf31126b900bf38
Autor:
Ruohao Xu, Miao Wu, Yawen Wang, Chao Li, Lingji Zeng, Yulian Wang, Maozhi Xiao, Xiaomei Chen, Suxia Geng, Peilong Lai, Xin Du, Jianyu Weng
Publikováno v:
Molecular Medicine, Vol 29, Iss 1, Pp 1-15 (2023)
Abstract Background Myofibroblasts (MFB), one of the major effectors of pathologic fibrosis, mainly derived from the activation of fibroblast to myofibroblast transition (FMT). Although MFBs were historically considered terminally differentiated cell
Externí odkaz:
https://doaj.org/article/8979a0f83a9b49db8b0e55c7d540f09f
Autor:
Parul Singh, Syed Azmal Ali
Publikováno v:
Cell Insight, Vol 2, Iss 5, Pp 100123- (2023)
Mammary gland growth and differentiation predominantly rely on stromal-epithelial cellular communication. Specifically, mammary adipocytes play a crucial role in ductal morphogenesis, as well as in the proliferation and differentiation of mammary epi
Externí odkaz:
https://doaj.org/article/4dcf26c310834fdf8d3733d2cd20d3c3
Autor:
Wilson CJ Chung, Pei-San Tsai
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Neurons that secrete gonadotropin-releasing hormone (GnRH) drive vertebrate reproduction. Genetic lesions that disrupt these neurons in humans lead to congenital hypogonadotropic hypogonadism (CHH) and reproductive failure. Studies on CHH have largel
Externí odkaz:
https://doaj.org/article/c543efc95bb54bd1a391787d41ad9a36
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Diabetes mellitus is the most common metabolic disease associated with impaired wound healing. Recently, Schwann cells (SCs), the glia of the peripheral nervous system, have been suggested to accelerate normal skin wound healing. However, the roles o
Externí odkaz:
https://doaj.org/article/b7546075e1d54c358ad0895e8759f2c8
Autor:
Nientied, Peter
Publikováno v:
International Journal of Tourism Cities, 2020, Vol. 7, Issue 2, pp. 344-360.
Externí odkaz:
http://www.emeraldinsight.com/doi/10.1108/IJTC-03-2020-0033
Autor:
Sultana Mehbuba Hossain, Gregory Gimenez, Peter A. Stockwell, Peter Tsai, Cristin G. Print, Janusz Rys, Bozena Cybulska-Stopa, Magda Ratajska, Agnieszka Harazin-Lechowska, Suzan Almomani, Christopher Jackson, Aniruddha Chatterjee, Michael R. Eccles
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Melanoma is a highly aggressive skin cancer, which, although highly immunogenic, frequently escapes the body’s immune defences. Immune checkpoint inhibitors (ICI), such as anti-PD1, anti-PDL1, and anti-CTLA4 antibodies lead to reactivation of immun
Externí odkaz:
https://doaj.org/article/3a823aa5363644c89dd26356837eee0b
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