Mechanistic insight into protein modification and sulfur mobilization activities of noncanonical E1 and associated ubiquitin-like proteins of Archaea.

Autor: Hepowit NL; Department of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, USA., de Vera IM; Department of Molecular Therapeutics, The Scripps Research Institute, Scripps Florida, Jupiter, FL, USA., Cao S; Department of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, USA., Fu X; Department of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, USA., Wu Y; Department of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, USA., Uthandi S; Department of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, USA., Chavarria NE; Department of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, USA., Englert M; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA., Su D; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA., Sӧll D; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.; Department of Chemistry, Yale University, New Haven, CT, USA., Kojetin DJ; Department of Molecular Therapeutics, The Scripps Research Institute, Scripps Florida, Jupiter, FL, USA., Maupin-Furlow JA; Department of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, USA. jmaupin@ufl.edu.; Genetics Institute, University of Florida, Gainesville, FL, USA. jmaupin@ufl.edu.

Publikováno v: The FEBS journal [FEBS J] 2016 Oct; Vol. 283 (19), pp. 3567-3586.

Ebselen, a Small-Molecule Capsid Inhibitor of HIV-1 Replication.

Autor: Thenin-Houssier S; Department of Immunology and Microbial Sciences, The Scripps Research Institute, Jupiter, Florida, USA., de Vera IM; Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, Florida, USA., Pedro-Rosa L; Department of Molecular Therapeutics, Molecular Screening Center, The Scripps Research Institute, Jupiter, Florida, USA., Brady A; Department of Immunology and Microbial Sciences, The Scripps Research Institute, Jupiter, Florida, USA., Richard A; Department of Immunology and Microbial Sciences, The Scripps Research Institute, Jupiter, Florida, USA., Konnick B; Department of Immunology and Microbial Sciences, The Scripps Research Institute, Jupiter, Florida, USA., Opp S; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA., Buffone C; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA., Fuhrmann J; Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, Florida, USA., Kota S; Department of Cancer Biology, The Scripps Research Institute, Jupiter, Florida, USA., Billack B; Department of Pharmaceutical Sciences, St. John's University, Jamaica, New York, USA., Pietka-Ottlik M; Department of Organic and Pharmaceutical Technology, Faculty of Chemistry, Wroclaw University of Technology, Wroclaw, Poland., Tellinghuisen T; Department of Immunology and Microbial Sciences, The Scripps Research Institute, Jupiter, Florida, USA., Choe H; Department of Immunology and Microbial Sciences, The Scripps Research Institute, Jupiter, Florida, USA., Spicer T; Department of Molecular Therapeutics, Molecular Screening Center, The Scripps Research Institute, Jupiter, Florida, USA., Scampavia L; Department of Molecular Therapeutics, Molecular Screening Center, The Scripps Research Institute, Jupiter, Florida, USA., Diaz-Griffero F; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA., Kojetin DJ; Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, Florida, USA., Valente ST; Department of Immunology and Microbial Sciences, The Scripps Research Institute, Jupiter, Florida, USA svalente@scripps.edu.

Publikováno v: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2016 Mar 25; Vol. 60 (4), pp. 2195-208. Date of Electronic Publication: 2016 Mar 25 (Print Publication: 2016).

Distal substitutions drive divergent DNA specificity among paralogous transcription factors through subdivision of conformational space.

Autor: Hudson WH; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322;, Kossmann BR; Department of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30302;, de Vera IM; Department of Molecular Therapeutics, The Scripps Research Institute, Scripps Florida, Jupiter, FL 33458;, Chuo SW; Department of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30302;, Weikum ER; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322;, Eick GN; Institute of Ecology and Evolution, University of Oregon, Eugene, OR 97403;, Thornton JW; Department of Ecology and Evolution, University of Chicago, Chicago, IL 60637; Department of Human Genetics, University of Chicago, Chicago, IL 60637., Ivanov IN; Department of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30302;, Kojetin DJ; Department of Molecular Therapeutics, The Scripps Research Institute, Scripps Florida, Jupiter, FL 33458;, Ortlund EA; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322; eric.ortlund@emory.edu.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2016 Jan 12; Vol. 113 (2), pp. 326-31. Date of Electronic Publication: 2015 Dec 29.

Synthesis, molecular docking, and in vivo antidiabetic evaluation of new benzylidene-2,4-thiazolidinediones as partial PPAR-γ agonists.

Autor: Najmi, Asim¹ (AUTHOR) anajmi@jazanu.edu.sa, Alam, Md Shamsher¹ (AUTHOR), Thangavel, Neelaveni¹ (AUTHOR), Taha, Manal M. E.² (AUTHOR), Meraya, Abdulkarim M.³ (AUTHOR), Albratty, Mohammed¹ (AUTHOR), Alhazmi, Hassan A.^1,2,4 (AUTHOR), Ahsan, Waquar¹ (AUTHOR), Haque, Anzarul⁵ (AUTHOR), Azam, Faizul⁶ (AUTHOR)

Publikováno v: Scientific Reports. 11/14/2023, Vol. 13 Issue 1, p1-17. 17p.

Effects of PRE and POST therapy drug-pressure selected mutations on HIV-1 protease conformational sampling.

Autor: Carter JD; Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA., Gonzales EG; Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA., Huang X; Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA., Smith AN; Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA., de Vera IM; Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA., D'Amore PW; Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA., Rocca JR; Advanced Magnetic Resonance Imaging and Spectroscopy Facility, McKnight Brain Institute, University of Florida, Gainesville, FL 32610, USA., Goodenow MM; Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL 32610-3633, USA., Dunn BM; Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, FL 32610-0245, USA., Fanucci GE; Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA. Electronic address: fanucci@chem.ufl.edu.

Publikováno v: FEBS letters [FEBS Lett] 2014 Aug 25; Vol. 588 (17), pp. 3123-8. Date of Electronic Publication: 2014 Jun 28.