Comparing the performance of FAM19A4 methylation analysis, cytology and HPV16/18 genotyping for the detection of cervical (pre)cancer in high-risk HPV-positive women of a gynecologic outpatient population (COMETH study)

Autor: Luttmer, R, De Strooper, LMA, Berkhof, J, Snijders, PJF, Dijkstra, MG, Uijterwaal, MH, Steenbergen, RDM, van Kemenade, Folkert, Rozendaal, L, Helmerhorst, Verheijen, RHM, ter Harmsel, WA, van Baal, WM, Graziosi, PGCM, Quint, WGV, Heideman, DAM, Meijer, CJLM

Publikováno v: International Journal of Cancer, 138(4), 992-1002. Wiley-Liss Inc.

Recently, DNA methylation analysis of FAM19A4 in cervical scrapes has been shown to adequately detect high-grade cervical intraepithelial neoplasia and cervical cancer (>= CIN3) in high-risk HPV (hrHPV)-positive women. Here, we compared the clinical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::46aa91e81ce450d678653805210d1a2b
https://pure.eur.nl/en/publications/ac545a25-f6e5-4fb8-b727-a9b68b693348

Long-term CIN3+ risk of HPV positive women after triage with FAM19A4/miR124-2 methylation analysis.

Autor: Dick S; Amsterdam UMC, Vrije Universiteit Amsterdam, Pathology, Cancer Center Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands., Kremer WW; Amsterdam UMC, Vrije Universiteit Amsterdam, Pathology, Cancer Center Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands., De Strooper LMA; Amsterdam UMC, Vrije Universiteit Amsterdam, Pathology, Cancer Center Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands., Lissenberg-Witte BI; Amsterdam UMC, Vrije Universiteit Amsterdam, Epidemiology and Biostatistics, De Boelelaan 1117, Amsterdam, the Netherlands., Steenbergen RDM; Amsterdam UMC, Vrije Universiteit Amsterdam, Pathology, Cancer Center Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands., Meijer CJLM; Amsterdam UMC, Vrije Universiteit Amsterdam, Pathology, Cancer Center Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands., Berkhof J; Amsterdam UMC, Vrije Universiteit Amsterdam, Epidemiology and Biostatistics, De Boelelaan 1117, Amsterdam, the Netherlands., Heideman DAM; Amsterdam UMC, Vrije Universiteit Amsterdam, Pathology, Cancer Center Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands. Electronic address: dam.heideman@vumc.nl.

Publikováno v: Gynecologic oncology [Gynecol Oncol] 2019 Aug; Vol. 154 (2), pp. 368-373. Date of Electronic Publication: 2019 Jun 08.

Defining hrHPV genotypes in cervical intraepithelial neoplasia by laser capture microdissection supports reflex triage of self-samples using HPV16/18 and FAM19A4/miR124-2 methylation.

Autor: Leeman A; DDL Diagnostic Laboratory, Rijswijk, the Netherlands., Ebisch RMF; Department of Obstetrics and Gynaecology, Radboud university medical center, Nijmegen, the Netherlands., Kasius A; DDL Diagnostic Laboratory, Rijswijk, the Netherlands., Bosgraaf RP; Department of Obstetrics and Gynaecology, Radboud university medical center, Nijmegen, the Netherlands., Jenkins D; DDL Diagnostic Laboratory, Rijswijk, the Netherlands., van de Sandt MM; DDL Diagnostic Laboratory, Rijswijk, the Netherlands., de Strooper LMA; Amsterdam UMC, Vrije Universiteit Amsterdam, Pathology, Cancer Center Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands., Heideman DAM; Amsterdam UMC, Vrije Universiteit Amsterdam, Pathology, Cancer Center Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands., Snijders PJF; Amsterdam UMC, Vrije Universiteit Amsterdam, Pathology, Cancer Center Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands., Massuger LFAG; Department of Obstetrics and Gynaecology, Radboud university medical center, Nijmegen, the Netherlands., Bekkers RLM; Department of Obstetrics and Gynaecology, Radboud university medical center, Nijmegen, the Netherlands; Department of Obstetrics and Gynaecology, Catharina Hospital, Eindhoven, the Netherlands., Meijer CJLM; Amsterdam UMC, Vrije Universiteit Amsterdam, Pathology, Cancer Center Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands., van Kemenade FJ; Erasmus Medical Center, Department of Pathology, Rotterdam, the Netherlands., Quint WGV; DDL Diagnostic Laboratory, Rijswijk, the Netherlands. Electronic address: wim.quint@ddl.nl., Melchers WJG; Department of Medical Microbiology, Radboud university medical center, Nijmegen, the Netherlands.

Publikováno v: Gynecologic oncology [Gynecol Oncol] 2018 Nov; Vol. 151 (2), pp. 311-318. Date of Electronic Publication: 2018 Sep 13.

Selection of women at risk for cervical cancer in an HIV-infected South African population.

Autor: Van Zummeren M; aCancer Centre Amsterdam, Department of Pathology, VU University Medical Centre, Amsterdam, The Netherlands bDepartment of Obstetrics and Gynaecology, Steve Biko Academic Hospital cDepartment of Medical Virology, University of Pretoria, and National Health Laboratory Service, Pretoria, South Africa dDepartment of Epidemiology and Biostatistics, VU University Medical Centre eSelf-screen B.V., Amsterdam, The Netherlands., Kremer WW, Van Aardt MC, Breytenbach E, Richter KL, Rozendaal L, Witte BI, De Strooper LMA, Hesselink AT, Heideman DAM, Snijders PJF, Steenbergen RDM, Dreyer G, Meijer CJLM

Publikováno v: AIDS (London, England) [AIDS] 2017 Sep 10; Vol. 31 (14), pp. 1945-1953.

Validation of the FAM19A4/mir124-2 DNA methylation test for both lavage- and brush-based self-samples to detect cervical (pre)cancer in HPV-positive women.

Autor: De Strooper LMA; Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands. Electronic address: l.destrooper@vumc.nl., Verhoef VMJ; Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands. Electronic address: v.verhoef@vumc.nl., Berkhof J; Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands. Electronic address: h.berkhof@vumc.nl., Hesselink AT; Self-Screen B.V., Amsterdam, The Netherlands. Electronic address: b.hesselink@vumc.nl., de Bruin HME; Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands. Electronic address: hmedebruin@gmail.com., van Kemenade FJ; Department of Pathology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands. Electronic address: f.vankemenade@erasmusmc.nl., Bosgraaf RP; Department of Obstetrics and Gynaecology, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address: Remko.Bosgraaf@radboudumc.nl., Bekkers RLM; Department of Obstetrics and Gynaecology, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address: Ruud.Bekkers@radboudumc.nl., Massuger LFAG; Department of Obstetrics and Gynaecology, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address: Leon.Massuger@radboudumc.nl., Melchers WJG; Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address: Willem.Melchers@radboudumc.nl., Steenbergen RDM; Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands. Electronic address: r.steenbergen@vumc.nl., Snijders PJF; Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands. Electronic address: pjf.snijders@vumc.nl., Meijer CJLM; Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands. Electronic address: cjlm.meijer@vumc.nl., Heideman DAM; Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands. Electronic address: dam.heideman@vumc.nl.

Publikováno v: Gynecologic oncology [Gynecol Oncol] 2016 May; Vol. 141 (2), pp. 341-347. Date of Electronic Publication: 2016 Mar 03.