Zobrazeno 1 - 10
of 11
pro vyhledávání: '"De Sheng Ker"'
Autor:
Sofiyah Shaibullah, Nurshahirah Shuhaimi, De-Sheng Ker, Nurhikmah Mohd-Sharif, Kok Lian Ho, Aik-Hong Teh, Jitka Waterman, Thean-Hock Tang, Rui-Rui Wong, Sheila Nathan, Rahmah Mohamed, Min Jia Ng, Shin-Yee Fung, Mohd Anuar Jonet, Mohd Firdaus-Raih, Chyan Leong Ng
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Abstract Burkholderia pseudomallei is a highly versatile pathogen with ~25% of its genome annotated to encode hypothetical proteins. One such hypothetical protein, BPSL1038, is conserved across seven bacterial genera and 654 Burkholderia spp. Here, w
Externí odkaz:
https://doaj.org/article/363408bd549b45f28f536097f87f704a
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Actinoporins are a family of α-pore-forming toxins (α-PFTs) that have been identified in sea anemones. Recently, a freshwater Hydra Actinoporin-Like Toxin (HALT) gene family was found in Hydra magnipapillata. Unlike sea anemone actinoporin
Externí odkaz:
https://doaj.org/article/0740dde641204075ba41efc1b5dbeefa
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009740 (2021)
Nipah and its close relative Hendra are highly pathogenic zoonotic viruses, storing their ssRNA genome in a helical nucleocapsid assembly formed by the N protein, a major viral immunogen. Here, we report the first cryoEM structure for a Henipavirus R
Externí odkaz:
https://doaj.org/article/c60530bf710e4d7babc9fea8351a1771
Autor:
De-Sheng Ker, Sze Lei Pang, Noor Farhan Othman, Sekar Kumaran, Ee Fun Tan, Thiba Krishnan, Kok Gan Chan, Roohaida Othman, Maizom Hassan, Chyan Leong Ng
Publikováno v:
PeerJ, Vol 5, p e2961 (2017)
Background Sesquiterpenes are 15-carbon terpenes synthesized by sesquiterpene synthases using farnesyl diphosphate (FPP) as a substrate. Recently, a sesquiterpene synthase gene that encodes a 65 kDa protein was isolated from the aromatic plant Persic
Externí odkaz:
https://doaj.org/article/9a8bd9901d3e48f6945c4c6c011d9136
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Actinoporins are a family of α-pore-forming toxins (α-PFTs) that have been identified in sea anemones. Recently, a freshwater Hydra Actinoporin-Like Toxin (HALT) gene family was found in Hydra magnipapillata. Unlike sea anemone actinoporins that us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf541bfa7b2879c0c3f2deb2b4581611
https://doi.org/10.1038/s41598-021-99879-5
https://doi.org/10.1038/s41598-021-99879-5
Autor:
Yanchun, Peng, Alexander J, Mentzer, Guihai, Liu, Xuan, Yao, Zixi, Yin, Danning, Dong, Wanwisa, Dejnirattisai, Timothy, Rostron, Piyada, Supasa, Chang, Liu, César, López-Camacho, Jose, Slon-Campos, Yuguang, Zhao, David I, Stuart, Guido C, Paesen, Jonathan M, Grimes, Alfred A, Antson, Oliver W, Bayfield, Dorothy E D P, Hawkins, De-Sheng, Ker, Beibei, Wang, Lance, Turtle, Krishanthi, Subramaniam, Paul, Thomson, Ping, Zhang, Christina, Dold, Jeremy, Ratcliff, Peter, Simmonds, Thushan, de Silva, Paul, Sopp, Dannielle, Wellington, Ushani, Rajapaksa, Yi-Ling, Chen, Mariolina, Salio, Giorgio, Napolitani, Wayne, Paes, Persephone, Borrow, Benedikt M, Kessler, Jeremy W, Fry, Nikolai F, Schwabe, Malcolm G, Semple, J Kenneth, Baillie, Shona C, Moore, Peter J M, Openshaw, M Azim, Ansari, Susanna, Dunachie, Eleanor, Barnes, John, Frater, Georgina, Kerr, Philip, Goulder, Teresa, Lockett, Robert, Levin, Yonghong, Zhang, Ronghua, Jing, Ling-Pei, Ho, Richard J, Cornall, Christopher P, Conlon, Paul, Klenerman, Gavin R, Screaton, Juthathip, Mongkolsapaya, Andrew, McMichael, Julian C, Knight, Graham, Ogg
Publikováno v:
Nature immunology. 21(11)
The development of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines and therapeutics will depend on understanding viral immunity. We studied T cell memory in 42 patients following recovery from COVID-19 (28 with mild disease and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4a9297136ff57002dc5d66f91bec21ad
https://pubmed.ncbi.nlm.nih.gov/32895541
https://pubmed.ncbi.nlm.nih.gov/32895541
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 7, p e1009740 (2021)
PLoS Pathogens, Vol 17, Iss 7, p e1009740 (2021)
Nipah and its close relative Hendra are highly pathogenic zoonotic viruses, storing their ssRNA genome in a helical nucleocapsid assembly formed by the N protein, a major viral immunogen. Here, we report the first cryoEM structure for a Henipavirus R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e364205be29bae3c73c28f3ecc7b215
Publikováno v:
Phytochemistry. 173
The chemical formation of terpenes in nature is carried out by terpene synthases as the main biocatalysts to guide the carbocation intermediate to form structurally diverse compounds including acyclic, mono- and multiple cyclic products. Despite inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c42946990efabb226318865b65cfc027
https://pubmed.ncbi.nlm.nih.gov/32059132
https://pubmed.ncbi.nlm.nih.gov/32059132
Autor:
Oleg I. Klychnikov, Jake L. R. Smith, Oliver W. Bayfield, Dorothy E. D. P. Hawkins, Andrey Sysoev, Kristina V. Tugaeva, Alfred A. Antson, Nikolai N. Sluchanko, De Sheng Ker
Publikováno v:
Journal of Molecular Biology
The coronavirus nucleocapsid protein (N) controls viral genome packaging and contains numerous phosphorylation sites located within unstructured regions. Binding of phosphorylated SARS-CoV N to the host 14-3-3 protein in the cytoplasm was reported to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d373e2353b42d52c657f3e2d0054fb8
https://doi.org/10.1016/j.jmb.2021.166875
https://doi.org/10.1016/j.jmb.2021.166875
Autor:
De-Sheng, Ker, Sze Lei, Pang, Noor Farhan, Othman, Sekar, Kumaran, Ee Fun, Tan, Thiba, Krishnan, Kok Gan, Chan, Roohaida, Othman, Maizom, Hassan, Chyan Leong, Ng
Publikováno v:
PeerJ
Background Sesquiterpenes are 15-carbon terpenes synthesized by sesquiterpene synthases using farnesyl diphosphate (FPP) as a substrate. Recently, a sesquiterpene synthase gene that encodes a 65 kDa protein was isolated from the aromatic plant Persic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::54e1cf95e866fc47d4fb5c3ce9c0be91
https://pubmed.ncbi.nlm.nih.gov/28265494
https://pubmed.ncbi.nlm.nih.gov/28265494