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NLRP3 phosphorylation in its LRR domain critically regulates inflammasome assembly

Autor: Niu, Tingting, De Rosny, Charlotte, Chautard, Séverine, Rey, Amaury, Patoli, Danish, Groslambert, Marine, Cosson, Camille, Lagrange, Brice, Zhang, Zhirong, Visvikis, Orane, Hacot, Sabine, Hologne, Maggy, Walker, Olivier, Wong, Jeimin, Wang, Ping, Ricci, Roméo, Henry, Thomas, Boyer, Laurent, Petrilli, Virginie, Py, Bénédicte F.

Publikováno v: Nature Communications
Nature Communications, 2021, 12 (1), pp.Article number: 5862. ⟨10.1038/s41467-021-26142-w⟩
Nature Communications, Nature Publishing Group, 2021, 12 (1), ⟨10.1038/s41467-021-26142-w⟩
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)

NLRP3 controls the secretion of inflammatory cytokines IL-1β/18 and pyroptosis by assembling the inflammasome. Upon coordinated priming and activation stimuli, NLRP3 recruits NEK7 within hetero-oligomers that nucleate ASC and caspase-1 filaments, bu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5a76d3731f38b1bab2c263e131bb779d
https://hal.science/hal-03401509/file/s41467-021-26142-w.pdf

Functional diversity of NLRP3 gain-of-function mutants associated with CAPS autoinflammation

Autor: Cosson, Camille, Riou, Romane, Patoli, Danish, Niu, Tingting, Rey, Amaury, Groslambert, Marine, De Rosny, Charlotte, Chatre, Elodie, Allatif, Omran, Henry, Thomas, Venet, Fabienne, Milhavet, Florian, Boursier, Guilaine, Belot, Alexandre, Jamilloux, Yvan, Merlin, Etienne, Duquesne, Agnès, Grateau, Gilles, Savey, Léa, Jacques Maria, Alexandre Thibault, Pagnier, Anne, Poutrel, Solène, Lambotte, Olivier, Mallebranche, Coralie, Ardois, Samuel, Richer, Olivier, Lemelle, Irène, Rieux-Laucat, Frédéric, Bader-Meunier, Brigitte, Amoura, Zahir, Melki, Isabelle, Cuisset, Laurence, Touitou, Isabelle, Geyer, Matthias, Georgin-Lavialle, Sophie, Py, Bénédicte F.

Publikováno v: The Journal of Experimental Medicine; May 2024, Vol. 221 Issue: 5 pe20231200-e20231200, 1p

Docosahexaenoic acid inhibits both NLRP3 inflammasome assembly and JNK-mediated mature IL-1β secretion in 5-fluorouracil-treated MDSC: implication in cancer treatment.

Autor: Dumont, Adélie, de Rosny, Charlotte, Kieu, Trinh-Le-Vi, Perrey, Sabrina, Berger, Hélène, Fluckiger, Aurélie, Muller, Tania, Pais de Barros, Jean-Paul, Pichon, Laurent, Hichami, Aziz, Thomas, Charles, Rébé, Cédric, Ghiringhelli, François, Rialland, Mickaël

Publikováno v: Cell Death & Disease; Jul2019, Vol. 10 Issue 7, pN.PAG-N.PAG, 1p

Correction: Phenolic extract from oleaster (Olea europaea var. Sylvestris) leaves reduces colon cancer growth and induces caspase-dependent apoptosis in colon cancer cells via the mitochondrial apoptotic pathway.

Autor: Zeriouh, Wafa, Nani, Abdelhafid, Belarbi, Meriem, Dumont, Adélie, de Rosny, Charlotte, Aboura, Ikram, Ghanemi, Fatima Zahra, Murtaza, Babar, Patoli, Danish, Thomas, Charles, Apetoh, Lionel, Rébé, Cédric, Delmas, Dominique, Khan, Naim Akhtar, Ghiringhelli, François, Rialland, Mickael, Hichami, Aziz

Publikováno v: PLoS ONE; 4/20/2017, Vol. 12 Issue 4, p1-1, 1p