Zobrazeno 1 - 9
of 9
pro vyhledávání: '"De Ren Huang"'
Autor:
Brian Werneburg, De Ren Huang, Javier Zambrano, Barry Hendin, Sheri Rosenblatt, Sibyl Wray, Robert T. Naismith
Publikováno v:
Neurodegenerative Disease Management. 7:39-47
Aim: The objective of this Delphi analysis was to obtain consensus on injection-site reaction (ISR) experience and mitigation strategies for patients with relapsing-remitting multiple sclerosis switching from nonpegylated interferons (IFNs) to pegint
Autor:
Scott D. Newsome, Xiaojun You, Leslie Leahy, Vladimir Evilevitch, Christopher Robertson, June Halper, Guido Sabatella, Diego Centonze, De Ren Huang
Publikováno v:
International Journal of MS Care. 18:211-218
Background: Flu-like symptoms (FLSs) and injection-site reactions (ISRs) have been reported with interferon beta treatments for multiple sclerosis (MS). We sought to obtain consensus on the characteristics/management of FLSs/ISRs in patients with rel
Publikováno v:
Journal of Clinical Investigation. 108:425-435
Stromal-derived cell factor-1 alpha (SDF-1 alpha; CXCL12) and its receptor, CXCR4, are constitutively expressed on neuroepithelial cells and are believed to be involved in both development and pathological processes, such as AIDS-associated neurologi
Autor:
Magnus Björkholm, De Ren Huang, Qing Yi, Göran Holm, Chengyun Zheng, Li Liu, Ruihua Wu, Anders Österborg, Susanne B. Bergenbrant Glas, Anne Sundblad
Publikováno v:
International Journal of Cancer. 95:184-188
Multiple myeloma (MM) is a B-cell malignancy characterized by an accumulation of malignant plasma cells in the bone marrow. It is unclear whether genetic background could have an etiological impact on MM or influence the course of the disease. Interl
Autor:
Anne Sundblad, Qing Yi, Chengyun Zheng, Susanne Bergenbrant, Magnus Björkholm, Anders Österborg, Göran Holm, De Ren Huang
Publikováno v:
British Journal of Haematology. 109:39-45
Proinflammatory cytokines such as interleukin 6 (IL-6), tumour necrosis factor α (TNF-α) and IL-1β are considered to be involved in the pathogenesis of multiple myeloma (MM). In the present study, we examined a G/C polymorphism at position −174
Publikováno v:
British Journal of Haematology. 112:216-218
Multiple myeloma (MM) is a B-lineage malignancy with unknown aetiology. It has been considered that predisposing genetic factors might be implicated in the disease. In this study, the microsatellite polymorphism in the exon 3 of the cytotoxic T-lymph
Autor:
Elizabeth A. Hartman, De Ren Huang
Publikováno v:
Current HIV/AIDS reports. 5(3)
Significant advances in our understanding of progressive multifocal leukoencephalopathy (PML) and its causative agent, JC virus, have been made since PML was first described 50 years ago. However, immune reconstitution remains the only proven, effect
Autor:
Jar Chi Lee, Richard M. Ransohoff, Dan R. Littman, Donald N. Cook, Volodymyr Kostenko, Erik P. Pioro, Astrid E. Cardona, Ineke M. Dijkstra, Margaret E. Sasse, Ranjan Dutta, Steffen Jung, Stephen M. Dombrowski, Sergio A. Lira, De Ren Huang, Grahame J. Kidd, Sandra M. Cardona
Publikováno v:
Nature neuroscience. 9(7)
Microglia, the resident inflammatory cells of the CNS, are the only CNS cells that express the fractalkine receptor (CX3CR1). Using three different in vivo models, we show that CX3CR1 deficiency dysregulates microglial responses, resulting in neuroto
Autor:
De Ren Huang, Milton H. Werner
Publikováno v:
Journal of Neurovirology
Sixty-three natalizumab-treated patients with relapsing multiple sclerosis were screened for JC polyomavirus (JCV) viruria. Urinary-positive patients were longitudinally sampled for up to 24 weeks. Using methods that distinguish encapsidated virus fr