Immune cell targeted fumaric esters support a role of GPR109A as a primary target of monomethyl fumarate in vivo.

Autor: Straß S; Pharmaceutical Chemistry, Institute for Pharmaceutical Sciences, Eberhard Karls University Tübingen, Tübingen, Germany.; Synovo GmbH, Tübingen, Germany., Geiger J; Synovo GmbH, Tübingen, Germany., Cloos N; Synovo GmbH, Tübingen, Germany., Späth N; Synovo GmbH, Tübingen, Germany., Geiger S; Synovo GmbH, Tübingen, Germany., Schwamborn A; Synovo GmbH, Tübingen, Germany., De Oliveira da Cunha L; Synovo GmbH, Tübingen, Germany., Martorelli M; Pharmaceutical Chemistry, Institute for Pharmaceutical Sciences, Eberhard Karls University Tübingen, Tübingen, Germany.; Synovo GmbH, Tübingen, Germany., Guse JH; Synovo GmbH, Tübingen, Germany., Sandri TL; Synovo GmbH, Tübingen, Germany.; Institute of Tropical Medicine, Eberhard Karls University Tübingen, Tübingen, Germany., Burnet M; Synovo GmbH, Tübingen, Germany. michael.burnet@synovo.com., Laufer S; Pharmaceutical Chemistry, Institute for Pharmaceutical Sciences, Eberhard Karls University Tübingen, Tübingen, Germany.

Publikováno v: Inflammopharmacology [Inflammopharmacology] 2023 Jun; Vol. 31 (3), pp. 1223-1239. Date of Electronic Publication: 2023 Apr 01.