Increased cell-free mitochondrial DNA is a marker of ongoing inflammation and better neurocognitive function in virologically suppressed HIV-infected individuals

Autor: Perez-Santiago, Josue, De Oliveira, Michelli F, Var, Susanna R, Day, Tyler RC, Woods, Steven P, Gianella, Sara, Mehta, Sanjay R

Publikováno v: Journal of neurovirology, vol 23, iss 2
Perez-Santiago, Josue; De Oliveira, Michelli F; Var, Susanna R; Day, Tyler RC; Woods, Steven P; Gianella, Sara; et al.(2017). Increased cell-free mitochondrial DNA is a marker of ongoing inflammation and better neurocognitive function in virologically suppressed HIV-infected individuals. JOURNAL OF NEUROVIROLOGY, 23(2), 283-289. doi: 10.1007/s13365-016-0497-5. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/98c6k4hz

Cell-free mitochondrial DNA (mtDNA) is a highly immunogenic molecule that is associated with several inflammatory conditions and with neurocognitive impairment during untreated HIV infection. Here, we investigate how cell-free mtDNA in cerebrospinal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::11b84aabfa343f47b0bccd3c961dd08a
https://escholarship.org/uc/item/98c6k4hz

Increased cell-free mitochondrial DNA is a marker of ongoing inflammation and better neurocognitive function in virologically suppressed HIV-infected individuals.

Autor: Pérez-Santiago J; University of California San Diego, 9500 Gilman Drive MC 0679, La Jolla, CA, 92093-0679, USA. joperez@ucsd.edu., De Oliveira MF; University of California San Diego, 9500 Gilman Drive MC 0679, La Jolla, CA, 92093-0679, USA., Var SR; Western Michigan University, Kalamazoo, MI, USA., Day TRC; Washington University, St. Louis, MI, USA., Woods SP; University of Houston, Houston, TX, USA., Gianella S; University of California San Diego, 9500 Gilman Drive MC 0679, La Jolla, CA, 92093-0679, USA., Mehta SR; University of California San Diego, 9500 Gilman Drive MC 0679, La Jolla, CA, 92093-0679, USA.; Veterans Administration San Diego Healthcare System, San Diego, CA, USA.

Publikováno v: Journal of neurovirology [J Neurovirol] 2017 Apr; Vol. 23 (2), pp. 283-289. Date of Electronic Publication: 2016 Dec 05.