Zobrazeno 1 - 10
of 55
pro vyhledávání: '"De Long Hao"'
Autor:
Ying-Ying Jin, Peng Zhang, Le-Le Liu, Xiang Zhao, Xiao-Qing Hu, Si-Zhe Liu, Ze-Kun Li, Qian Liu, Jian-Qiao Wang, De-Long Hao, Zhu-Qin Zhang, Hou-Zao Chen, De-Pei Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Despite the potential of small molecules and recombinant proteins to enhance the efficiency of homology-directed repair (HDR), single-stranded DNA (ssDNA) donors, as currently designed and chemically modified, remain suboptimal for precise g
Externí odkaz:
https://doaj.org/article/0ebf624eb8b44729962c9f2861c9c6f4
Autor:
Yang-Nan Ding, Ting-Ting Wang, Shuang-Jie Lv, Xiaoqiang Tang, Zi-Yu Wei, Fang Yao, Han-Shi Xu, Yi-Nan Chen, Xiao-Man Wang, Hui-Yu Wang, He-Ping Wang, Zhu-Qin Zhang, Xiang Zhao, De-Long Hao, Li-Hong Sun, Zhou Zhou, Li Wang, Hou-Zao Chen, De-Pei Liu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-14 (2023)
Abstract Thoracic aortic aneurysms (TAAs) develop asymptomatically and are characterized by dilatation of the aorta. This is considered a life-threating vascular disease due to the risk of aortic rupture and without effective treatments. The current
Externí odkaz:
https://doaj.org/article/dc82478bacfb4180958ea3c5c6a9a96f
Autor:
Ran Zhang, Xu Wang, Jia-Hua Qu, Bing Liu, Peng Zhang, Tao Zhang, Peng-Cheng Fan, Xiao-Man Wang, Guang-Yuan Xiao, Ye Su, Yan Xie, Yue Liu, Jian-Fei Pei, Zhu-Qin Zhang, De-Long Hao, Ping Xu, Hou-Zao Chen, De-Pei Liu
Publikováno v:
iScience, Vol 17, Iss , Pp 155-166 (2019)
Summary: Both caloric restriction (CR) and mitochondrial proteostasis are linked to longevity, but how CR maintains mitochondrial proteostasis in mammals remains elusive. MicroRNAs (miRNAs) are well known for gene silencing in cytoplasm and have rece
Externí odkaz:
https://doaj.org/article/962fd19d90e94da1b512780b10c251e0
Autor:
Jia-Hua Qu, Na Liu, Hou-Zao Chen, Shen-Shen Cui, Xiao-Man Wang, Ji-Min Cao, Kate S. Carroll, Qian Gao, Yang Zhang, Dapeng Ju, De-Pei Liu, Xun-Kai Li, Eric E. Zhang, Wen-Qi Li, Jia-Qi Fu, Jing Yang, Xiang Zhao, De-Long Hao, Jian-Fei Pei
Publikováno v:
Nature Cell Biology. 21:1553-1564
Redox balance, an essential feature of healthy physiological steady states, is regulated by circadian clocks, but whether or how endogenous redox signalling conversely regulates clockworks in mammals remains unknown. Here, we report circadian rhythms
Autor:
Yue Liu, Xu Wang, Ran Zhang, De-Pei Liu, De-Long Hao, Zhu-Qin Zhang, Peng Zhang, Guang-Yuan Xiao, Jia-Hua Qu, Jian-Fei Pei, Hou-Zao Chen, Yan Xie, Peng-Cheng Fan, Tao Zhang, Ye Su, Bing Liu, Xiao-Man Wang, Ping Xu
Publikováno v:
iScience, Vol 17, Iss, Pp 155-166 (2019)
iScience
iScience
Summary Both caloric restriction (CR) and mitochondrial proteostasis are linked to longevity, but how CR maintains mitochondrial proteostasis in mammals remains elusive. MicroRNAs (miRNAs) are well known for gene silencing in cytoplasm and have recen
Autor:
De-Pei Liu, Xiao Ya Pei, De Long Hao, Hou-Zao Chen, Xiang Zhao, Shuang Jie Lv, Zhu Qin Zhang, Yang Nan Ding
Publikováno v:
Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih. 35(1)
Objective Angiotensin Ⅱ (Ang Ⅱ)-induced vascular damage is a major risk of hypertension. However, the underlying molecular mechanism of AngⅡ-induced vascular damage is still unclear. In this study, we explored the novel mechanism associated wit
Autor:
Yue Liu, Jing Xu, Xiang Zhao, Tingting Wang, Jian-Fei Pei, De-Pei Liu, De-Long Hao, Hou-Zao Chen, Zhu-Qin Zhang, Li-Qin Cheng
Publikováno v:
Journal of Genetics and Genomics. 45:25-32
Abdominal aortic aneurysm (AAA) is a vascular degenerative disease. Macrophage polarization and the balance between classically activated macrophages (M1) and alternatively activated macrophages (M2) are crucial for AAA pathogenesis. The present stud
Autor:
Nan-Yu Wang, Shu-ting Liang, Xiao-Feng Chen, De-Long Hao, Hou-Zao Chen, Zhu-Qin Zhang, Xiang Zhao, Xiaoqiang Tang, Yun-Biao Lu, Ming-Hui Zou, Xiao-Man Wang, De-Pei Liu, Wei Zheng
Publikováno v:
Circulation. 136:2051-2067
Background: Pathological cardiac hypertrophy induced by stresses such as aging and neurohumoral activation is an independent risk factor for heart failure and is considered a target for the treatment of heart failure. However, the mechanisms underlyi
Autor:
De-Pei Liu, Xiaoqiang Tang, Xiang Lv, De Long Hao, Zhi-Guo Zhao, Xi-Zhou An, Xiang Zhao, Ran Zhang, Yu-Xuan Luo
Publikováno v:
Oncotarget
// Xi-Zhou An 1, * , Zhi-Guo Zhao 1, * , Yu-Xuan Luo 1 , Ran Zhang 1 , Xiao-Qiang Tang 1 , De-Long Hao 1 , Xiang Zhao 1 , Xiang Lv 1 , De-Pei Liu 1 1 State Key Laboratory of Medical Molecular Biology, Department of Biochemistry and Molecular Biology,
Autor:
Jian-Fei, Pei, Xun-Kai, Li, Wen-Qi, Li, Qian, Gao, Yang, Zhang, Xiao-Man, Wang, Jia-Qi, Fu, Shen-Shen, Cui, Jia-Hua, Qu, Xiang, Zhao, De-Long, Hao, Dapeng, Ju, Na, Liu, Kate S, Carroll, Jing, Yang, Eric Erquan, Zhang, Ji-Min, Cao, Hou-Zao, Chen, De-Pei, Liu
Publikováno v:
Nature cell biology. 21(12)
Redox balance, an essential feature of healthy physiological steady states, is regulated by circadian clocks, but whether or how endogenous redox signalling conversely regulates clockworks in mammals remains elusive. Here, we report circadian rhythms