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Clinical significance of complex karyotype at diagnosis in pediatric and adult patients with de novo acute promyelocytic leukemia treated with ATRA and chemotherapy

Autor: Labrador J, Luno E, Vellenga E, Brunet S, Gonzalez-Campose J, Chillon M, Holowiecka A, Esteve J, Bergua J, Gonzalez-Sanmiguel J, Gil C, Tormo M, Salamero O, Manso F, Fernandez I, de laSerna J, Moreno M, Perez-Encinas M, Krsnik I, Ribera J, Cervera J, Calasanz M, Boluda B, Sobas M, Lowenberg B, Sanz M, Montesinos P, Palmer L, Ciarlo S, Bezares F, Rojas F, Longoni H, Gelemur M, Fazio P, Canepa C, Saba S, Balladares G, Negri P, Giunta M, Milone J, Prates M, Lafalse D, Sossa C, Jaramillo F, Mayer J, Protivankova M, Scwarz J, Holowiecka-Goral A, Jakubas B, Skret-Norwicz A, Bizgalska-Skrzypek P, Pluta A, Becht R, Kielbinski M, Watek M, Paluszewska M, Gadomska A, Rzenno E, Piszcz J, Ejduk A, Dobrzanska J, Calbecka M, Kostyra A, Malek M, Grosicki S, Knopinska W, Beltran de Heredia J, Hernandez J, Arias J, Ramos F, Roman A, de la Serna J, Negri S, Rayon C, Fernandez-Calvo F, Diaz-Mediavilla J, Olave M, Amutio E, Pedro C, Gorosquieta A, Viguria M, Zudaire M, Molero T, Sayas M, Guardia R, Rivas C, Esquembre C, Garcia R, Alcala A, Lopez J, Rubio V, Amigo M, Linares M, Gonzalez San Miguel J, Deben G, Escoda L, de la Camara R, Molines A, Loureiro C, Allegue M, Amador L, Marti J, Madero L, Lassaletta A, Cabezudo M, Garcia-Larana J, Rojas R, Ortega F, Penarrubia M, Puente F, Lopez-Ibor B, Ibanez J, Sanchez P, Novo A, Font L, Guinea J, Montero A, Gonzalez M, Martin G, Martinez J, Verdeguer A, Garcia P, Conde E, Garcia J, Capote F, Bueno J, Bastida P, Rubio A, Fuster J, Gonzalez J, Perez I, Molina J, Mateos M, Ardaiz M, Rodriguez-calvillo M, Poderos C, Arnan M, Duarte R, Diaz-Morfa M, Martin-Chacon E, Calvo-Villas J, Garcia-Belmonte D, Hernandez-Maraver D, Ossenkoppele G, van der Lelie J, Sonneveld P, Zijlmans M, Maertens J, de Valk B, Wijermans P, de Groot M, Schouten H, Biesma D, Kooy M, de Lisa E, PETHEMA Grp, HOVON Grp, PALG Grp, GATLA Grp

Publikováno v: Leukemia & lymphoma
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
LEUKEMIA & LYMPHOMA
r-FISABIO. Repositorio Institucional de Producción Científica
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Leukemia & Lymphoma
r-FIHGUV. Repositorio Institucional de Producción Científica de la Fundación de Investigación del Hospital General de Valencia

Although additional cytogenetic abnormalities (ACA) do not affect the prognosis of patients with t(15;17) acute promyelocytic leukemia (APL), the role of a complex karyotype (CK) is yet to be clarified. We aimed to investigate the relationship of CK

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4d8f98dfbba4745776336cc5815100f5
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=10070

Risk-adapted treatment of acute promyelocytic leukemia based on all-trans retinoic acid and anthracycline with addition of cytarabine in consolidation therapy for high-risk patients: further improvements in treatment outcome

Autor: Sanz, M.A., Montesinos, P., Rayon, C., Holowiecka, A., de la Serna, J., Milone, G., de Lisa, E., Brunet, S., Rubio, V., Ribera, J.M., Rivas, C, Krsnik, I., Bergua, J., Gonzalez, J., Diaz-Mediavilla, J., Rojas, R., Manso, F., Ossenkoppele, G.J., Gonzalez, J.D., Lowenberg, B., Pethema, G., Hovon, G.

Publikováno v: BLOOD
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Sanz, M A, Montesinos, P, Rayon, C, Holowiecka, A, de la Serna, J, Milone, G, de Lisa, E, Brunet, S, Rubio, V, Ribera, J M, Rivas, C, Krsnik, I, Bergua, J, Gonzalez, J, Diaz-Mediavilla, J, Rojas, R, Manso, F, Ossenkoppele, G J, Gonzalez, J D, Lowenberg, B, Pethema, G & Hovon, G 2010, ' Risk-adapted treatment of acute promyelocytic leukemia based on all-trans retinoic acid and anthracycline with addition of cytarabine in consolidation therapy for high-risk patients: further improvements in treatment outcome ', Blood, vol. 115, no. 25, pp. 5137-5146 . https://doi.org/10.1182/blood-2010-01-266007
Blood, 115(25), 5137-5146. American Society of Hematology
Blood
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe

A risk-adapted strategy based on all-trans retinoic acid (ATRA) and anthracycline monochemotherapy (PETHEMALPA99 trial) has demonstrated a high antileukemic efficacy in acute promyelocytic leukemia. We designed a new trial (LPA2005) with the objectiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88f1b4a8b486e5959aca3045099dce24
https://doi.org/10.1182/blood-2010-01-266007

IDENTIFICATION OF THE ANTIMICROBIAL ACTIVITY FROM OCTOPUS VULGARIS HAEMOCYTES

Autor: TRONCONE, LUCA, POLESE, GIANLUCA, DI COSMO, ANNA, De Lisa E.

The marine environment comprises complex ecosystems and many of organisms are known to possess bioactive components as a common means of self-defence or for the protections of eggs and embryos. Lately, many bioactive compounds have been extracted, ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3730::e55573c978fbe45d841c1744f21a3e80
http://hdl.handle.net/11588/508049

Charactherization of cytoplasmic PARP in the brain of octopus vulgaris

Autor: De Lisa E., DE MAIO, ANNA, Topo E., FARAONE MENNELLA, MARIA ROSARIA, DI COSMO, ANNA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3730::3479da4d4f3ae138e7d26ea97bd54ef9
http://hdl.handle.net/11588/598237