Cough as Noninvasive Biomarker for Monitoring Tuberculosis Treatment: A Proof-of-Concept Study.

Autor: Janssen S; TASK Cape Town, South Africa., Upton CM; TASK Cape Town, South Africa., De Jager VR; TASK Cape Town, South Africa., Faraj A; Uppsala University Uppsala, Sweden., Pahar M; Stellenbosch University Stellenbosch, South Africa., Miranda IDS; Federal University of Recôncavo da Bahia Bahia, Brazil., Diacon AH; TASK Cape Town, South Africa., Simonsson USH; Uppsala University Uppsala, Sweden., Niesler TR; Stellenbosch University Stellenbosch, South Africa.

Publikováno v: Annals of the American Thoracic Society [Ann Am Thorac Soc] 2023 Dec; Vol. 20 (12), pp. 1822-1825.

Fourteen-day PET/CT imaging to monitor drug combination activity in treated individuals with tuberculosis.

Autor: Xie YL; Division of Infectious Diseases, Department of Medicine, Rutgers New Jersey Medical School, Newark, NJ 07103, USA., de Jager VR; TASK Applied Science, Cape Town 7500, South Africa., Chen RY; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD 20892, USA.; Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town 7925, South Africa., Dodd LE; Biostatistics Research Branch, Division of Clinical Research, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD 20892, USA., Paripati P; Imaging Group, NET ESolutions Inc., McLean, VA 22102, USA., Via LE; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD 20892, USA.; Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town 7925, South Africa., Follmann D; Biostatistics Research Branch, Division of Clinical Research, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD 20892, USA., Wang J; Clinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA., Lumbard K; Clinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA., Lahouar S; Imaging Group, NET ESolutions Inc., McLean, VA 22102, USA., Malherbe ST; Department of Science and Technology-National Research Foundation Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town 7600, South Africa., Andrews J; Microbial Pathogenesis, Yale University, New Haven, CT 06520, USA., Yu X; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD 20892, USA., Goldfeder LC; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD 20892, USA., Cai Y; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD 20892, USA., Arora K; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD 20892, USA., Loxton AG; Department of Science and Technology-National Research Foundation Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town 7600, South Africa., Vanker N; TASK Applied Science, Cape Town 7500, South Africa., Duvenhage M; Clinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA., Winter J; Catalysis Foundation for Health, San Ramon, CA 94583, USA., Song T; Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town 7925, South Africa., Walzl G; Department of Science and Technology-National Research Foundation Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town 7600, South Africa., Diacon AH; TASK Applied Science, Cape Town 7500, South Africa.; Department of Medicine, Stellenbosch University, Cape Town 7505, South Africa., Barry CE 3rd; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD 20892, USA. cbarry@niaid.nih.gov.; Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town 7925, South Africa.

Publikováno v: Science translational medicine [Sci Transl Med] 2021 Feb 03; Vol. 13 (579).

Optimizing β-Lactams against Tuberculosis.

Autor: de Jager VR; TASK Applied ScienceCape Town, South Africa., Vanker N; TASK LaboratoryCape Town, South Africa., van der Merwe L; TASK Applied ScienceCape Town, South Africa., van Brakel E; TASK Applied ScienceCape Town, South Africa., Muliaditan M; GlaxoSmithKlineStevenage, United Kingdomand., Diacon AH; TASK Applied ScienceCape Town, South Africa.; Stellenbosch UniversityCape Town, South Africa.

Publikováno v: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2020 May 01; Vol. 201 (9), pp. 1155-1157.

Fourteen-Day Bactericidal Activity, Safety, and Pharmacokinetics of Linezolid in Adults with Drug-Sensitive Pulmonary Tuberculosis.

Autor: Diacon AH; Division of Pulmonology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa ahd@sun.ac.za.; Task Applied Science, Bellville, South Africa., De Jager VR; Task Applied Science, Bellville, South Africa., Dawson R; Division of Pulmonology, Department of Medicine, Groote Schuur Hospital and University of Cape Town Lung Institute, Cape Town, South Africa., Narunsky K; Division of Pulmonology, Department of Medicine, Groote Schuur Hospital and University of Cape Town Lung Institute, Cape Town, South Africa., Vanker N; Task Laboratory, Parow, South Africa., Burger DA; Department of Statistics, University of Pretoria, Pretoria, South Africa., Everitt D; TB Alliance, New York, New York, USA., Pappas F; TB Alliance, New York, New York, USA., Nedelman J; TB Alliance, New York, New York, USA., Mendel CM; TB Alliance, New York, New York, USA.

Publikováno v: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2020 Mar 24; Vol. 64 (4). Date of Electronic Publication: 2020 Mar 24 (Print Publication: 2020).