Zobrazeno 1 - 10
of 1 159
pro vyhledávání: '"De Haas, A P"'
Autor:
van Haren, Hans, de Haas, Henk
Turbulent water motions are important for the exchange of momentum, heat, nutrients, and suspended matter including sediments in the deep-sea that is generally stably stratified in density. To maintain ocean-density stratification, an irreversible di
Externí odkaz:
http://arxiv.org/abs/2408.06680
Autor:
Gabriel, Iason, Manzini, Arianna, Keeling, Geoff, Hendricks, Lisa Anne, Rieser, Verena, Iqbal, Hasan, Tomašev, Nenad, Ktena, Ira, Kenton, Zachary, Rodriguez, Mikel, El-Sayed, Seliem, Brown, Sasha, Akbulut, Canfer, Trask, Andrew, Hughes, Edward, Bergman, A. Stevie, Shelby, Renee, Marchal, Nahema, Griffin, Conor, Mateos-Garcia, Juan, Weidinger, Laura, Street, Winnie, Lange, Benjamin, Ingerman, Alex, Lentz, Alison, Enger, Reed, Barakat, Andrew, Krakovna, Victoria, Siy, John Oliver, Kurth-Nelson, Zeb, McCroskery, Amanda, Bolina, Vijay, Law, Harry, Shanahan, Murray, Alberts, Lize, Balle, Borja, de Haas, Sarah, Ibitoye, Yetunde, Dafoe, Allan, Goldberg, Beth, Krier, Sébastien, Reese, Alexander, Witherspoon, Sims, Hawkins, Will, Rauh, Maribeth, Wallace, Don, Franklin, Matija, Goldstein, Josh A., Lehman, Joel, Klenk, Michael, Vallor, Shannon, Biles, Courtney, Morris, Meredith Ringel, King, Helen, Arcas, Blaise Agüera y, Isaac, William, Manyika, James
This paper focuses on the opportunities and the ethical and societal risks posed by advanced AI assistants. We define advanced AI assistants as artificial agents with natural language interfaces, whose function is to plan and execute sequences of act
Externí odkaz:
http://arxiv.org/abs/2404.16244
Autor:
Louise de Haas, Bastiaan van Hoorn, Veronique van de Lücht, N. Schep, M. Dijkgraaf, M. van Heijl, MUSCAT Trial Collaborator group
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background Guidelines recommend operative treatment followed by cast immobilization for acute complete ulnar collateral ligament (UCL) ruptures, including Stener lesions. This recommendation is based on expert opinion, anatomic theories, and
Externí odkaz:
https://doaj.org/article/a8bc821b6e3047e9a5bad8f8cd8a8bc6
Autor:
Andrea Hermann, Christoph Benke, Carlo R. Blecker, Benjamin de Haas, Yifei He, Stefan G. Hofmann, Jona R. Iffland, Johanna Jengert-Stahl, Tilo Kircher, Katrin Leinweber, Marcel Linka, Christoph Mulert, Marie K. Neudert, Ann-Kathrin Noll, Christiane A. Melzig, Winfried Rief, Constantin Rothkopf, Axel Schäfer, Christina V. Schmitter, Verena Schuster, Rudolf Stark, Benjamin Straube, Raphaela I. Zimmer, Lukas Kirchner
Publikováno v:
BMC Psychiatry, Vol 24, Iss 1, Pp 1-18 (2024)
Abstract Background Emotional disorders such as depression and anxiety disorders share substantial similarities in their etiology and treatment. In recent decades, these commonalities have been increasingly recognized in classification systems and tr
Externí odkaz:
https://doaj.org/article/75cf72a26e8f49bcb743532e6fe45019
Autor:
Sjors P. A. van der Lans, Bart W. Bardoel, Maartje Ruyken, Carla J. C. de Haas, Stan Baijens, Remy M. Muts, Lisette M. Scheepmaker, Piet C. Aerts, Marije F. L. van ’t Wout, Johannes Preiner, Renoud J. Marijnissen, Janine Schuurman, Frank J. Beurskens, Priscilla F. Kerkman, Suzan H. M. Rooijakkers
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Antibody-dependent complement activation plays a key role in the natural human immune response to infections. Currently, the understanding of which antibody-antigen combinations drive a potent complement response on bacteria is limited. Here
Externí odkaz:
https://doaj.org/article/a558f4acbc8844f0b4f524c388b29ef9
Autor:
Chang Chen, Ketan A. Ganar, Robbert J. de Haas, Nele Jarnot, Erwin Hogeveen, Renko de Vries, Siddharth Deshpande
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Compartmentalization is a vital aspect of living cells to orchestrate intracellular processes. In a similar vein, constructing dynamic and responsive sub-compartments is key to synthetic cell engineering. In recent years, liquid-liquid phase
Externí odkaz:
https://doaj.org/article/30807c6d68a8445baed61cfd79299700
Autor:
Frerich M. Masson, Salvör Káradóttir, Sjors P. A. van der Lans, Dennis J. Doorduijn, Carla J. C. de Haas, Suzan H. M. Rooijakkers, Bart W. Bardoel
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract The Gram-negative bacterium Klebsiella pneumoniae is an important human pathogen. Its treatment has been complicated by the emergence of multi-drug resistant strains. The human complement system is an important part of our innate immune resp
Externí odkaz:
https://doaj.org/article/95f5d01250314a67b82131f20bab09f7
Autor:
Andrea Vallés‐Martí, Richard R. deGoeij‐de Haas, Alex A. Henneman, Sander R. Piersma, Thang V. Pham, Jaco C. Knol, Joanne Verheij, Frederike Dijk, Hans Halfwerk, Elisa Giovannetti, Connie R. Jiménez, Maarten F. Bijlsma
Publikováno v:
Molecular Oncology, Vol 18, Iss 8, Pp 2020-2041 (2024)
Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease with a limited number of known driver mutations but considerable cancer cell heterogeneity. Phosphoproteomics provides a direct read‐out of aberrant signaling and the resultant clinic
Externí odkaz:
https://doaj.org/article/e8ff82023c7546bf9b7c1d4e26f666f5
Autor:
Marta Lopez-Cerda, Laura Lorenzo-Sanz, Victoria da Silva-Diz, Sandra Llop, Rosa M. Penin, Josep Oriol Bermejo, Richard de Goeij-de Haas, Sander R. Piersma, Thang V. Pham, Connie R. Jimenez, Juan Martin-Liberal, Purificación Muñoz
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-21 (2024)
Abstract Background Early cutaneous squamous cell carcinomas (cSCCs) generally show epithelial differentiation features and good prognosis, whereas advanced cSCCs present mesenchymal traits associated with tumor relapse, metastasis, and poor survival
Externí odkaz:
https://doaj.org/article/2d2e3cd7ff3f4fedbed353deaa311a0c
Autor:
Xabier Vergara, Anna G. Manjón, Marcel de Haas, Ben Morris, Ruben Schep, Christ Leemans, Anoek Friskes, Roderick L. Beijersbergen, Mathijs A. Sanders, René H. Medema, Bas van Steensel
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract DNA double-strand breaks are repaired by multiple pathways, including non-homologous end-joining (NHEJ) and microhomology-mediated end-joining (MMEJ). The balance of these pathways is dependent on the local chromatin context, but the underly
Externí odkaz:
https://doaj.org/article/6009cbab086a43759a3f31b9c33c7f5d