Zobrazeno 1 - 10 of 67 pro vyhledávání: '"De Francesco, EM"'
1
Targeting hypoxic cancer stem cells (CSCs) with Doxycycline:Implications for optimizing anti-angiogenic therapy
Autor: De Francesco, EM, Maggiolini, M, Tanowitz, HB, Sotgia, F, Lisanti, MP
Publikováno v: De Francesco, E M, Maggiolini, M, Tanowitz, H B, Sotgia, F & Lisanti, M P 2017, ' Targeting hypoxic cancer stem cells (CSCs) with Doxycycline : Implications for optimizing anti-angiogenic therapy ', Oncotarget, vol. 8, no. 34, pp. 56126-56142 . https://doi.org/10.18632/oncotarget.18445
Oncotarget
Here, we report new mechanistic insight into how chronic hypoxia increases 'stemness' in cancer cells. Using chemical inhibitors, we provide direct experimental evidence that ROS production and mitochondrial biogenesis are both required for the hypox
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::967737810a13d02d6dd83bc7d71ab41b
https://doi.org/10.18632/oncotarget.18445
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3
Editorial & Opinion
Harnessing sample preparation for RNA-sequencing toward a reliable bioinformatics analysis.
Autor: Talia M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Cesario E; Department of Cultures, Education and Society, University of Calabria, 87036, Rende, Italy., Cirillo F; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Scordamaglia D; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Di Dio M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Zicarelli A; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Mondino AA; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Occhiuzzi MA; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., De Francesco EM; Department of Medicine and Surgery, University of Enna 'Kore', 94100, Enna, Italy., Belfiore A; Endocrinology, Department of Clinical and Experimental Medicine, University of Catania, Garibaldi-Nesima Hospital, 95122, Catania, Italy., Miglietta AM; Breast and General Surgery Unit, Annunziata Hospital Cosenza, 87100, Cosenza, Italy., Di Dio M; Division of Urology, Department of Surgery, Annunziata Hospital, 87100, Cosenza, Italy., Capalbo C; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy.; Complex Operative Oncology Unit, Annunziata Hospital Cosenza, 87100, Cosenza, Italy., Maggiolini M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy. marcello.maggiolini@unical.it., Lappano R; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy. rosamaria.lappano@unical.it.
Publikováno v: Journal of translational medicine [J Transl Med] 2024 Sep 16; Vol. 22 (1), pp. 846. Date of Electronic Publication: 2024 Sep 16.
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4
Akademický článek
Cancer-associated fibroblasts (CAFs) gene signatures predict outcomes in breast and prostate tumor patients.
Autor: Talia M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy., Cesario E; Department of Cultures, Education and Society, University of Calabria, Rende, 87036, Italy., Cirillo F; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy., Scordamaglia D; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy., Di Dio M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy., Zicarelli A; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy., Mondino AA; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy., Occhiuzzi MA; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy., De Francesco EM; Department of Medicine and Surgery, University of Enna 'Kore', Enna, 94100, Italy., Belfiore A; Endocrinology, Department of Clinical and Experimental Medicine, University of Catania, Garibaldi-Nesima Hospital, Catania, 95122, Italy., Miglietta AM; Breast and General Surgery Unit, Annunziata Hospital Cosenza, Cosenza, 87100, Italy., Di Dio M; Division of Urology, Department of Surgery, Annunziata Hospital, Cosenza, 87100, Italy., Capalbo C; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy.; Complex Operative Oncology Unit, Annunziata Hospital Cosenza, Cosenza, 87100, Italy., Maggiolini M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy. marcello.maggiolini@unical.it., Lappano R; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy. rosamaria.lappano@unical.it.
Publikováno v: Journal of translational medicine [J Transl Med] 2024 Jun 27; Vol. 22 (1), pp. 597. Date of Electronic Publication: 2024 Jun 27.
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5
Akademický článek
The G Protein Estrogen Receptor (GPER) is involved in the resistance to the CDK4/6 inhibitor palbociclib in breast cancer.
Autor: Talia M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy., Cirillo F; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy., Scordamaglia D; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy., Di Dio M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy., Zicarelli A; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy., De Rosis S; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy., Miglietta AM; Breast and General Surgery Unit, Regional Hospital Cosenza, Cosenza, 87100, Italy., Capalbo C; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy.; Complex Operative Oncology Unit, Regional Hospital Cosenza, Cosenza, 87100, Italy., De Francesco EM; Department of Medicine and Surgery, University of Enna Kore, Enna, 94100, Italy., Belfiore A; Department of Clinical and Experimental Medicine, University of Catania, Garibaldi-Nesima Hospital, Catania, 95122, Italy., Grande F; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy., Rizzuti B; Department of Physics, CNR-NANOTEC, SS Rende (CS), University of Calabria, Rende, CS, 87036, Italy.; Institute of Biocomputation and Physics of Complex Systems (BIFI), Joint Unit GBsC-CSIC-BIFI, University of Zaragoza, Zaragoza, 50018, Spain., Occhiuzzi MA; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy., Fortino G; Department of Informatics, Modeling, Electronic, and System Engineering, University of Calabria, Rende, 87036, Italy., Guzzo A; Department of Informatics, Modeling, Electronic, and System Engineering, University of Calabria, Rende, 87036, Italy., Greco G; Department of Mathematics and Computer Science, University of Calabria, Cosenza, Italy., Maggiolini M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy. marcello.maggiolini@unical.it., Lappano R; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy. rosamaria.lappano@unical.it.
Publikováno v: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2024 Jun 18; Vol. 43 (1), pp. 171. Date of Electronic Publication: 2024 Jun 18.
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6
Akademický článek
GPER deletion triggers inhibitory effects in triple negative breast cancer (TNBC) cells through the JNK/c-Jun/p53/Noxa transduction pathway.
Autor: Cirillo F; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Talia M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Santolla MF; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Pellegrino M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Scordamaglia D; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Spinelli A; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., De Rosis S; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Giordano F; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Muglia L; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Zicarelli A; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Di Dio M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Rigiracciolo DC; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Via Adamello 16, 20139, Milano, Italy., Miglietta AM; Breast and General Surgery Unit, Regional Hospital Cosenza, 87100, Cosenza, Italy., Filippelli G; Oncology Department, Hospital of Paola, 87100, Cosenza, Italy., De Francesco EM; Endocrinology, Department of Clinical and Experimental Medicine, University of Catania, Garibaldi-Nesima Hospital, 95122, Catania, Italy., Belfiore A; Endocrinology, Department of Clinical and Experimental Medicine, University of Catania, Garibaldi-Nesima Hospital, 95122, Catania, Italy., Lappano R; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy. rosamaria.lappano@unical.it., Maggiolini M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy. marcello.maggiolini@unical.it.
Publikováno v: Cell death discovery [Cell Death Discov] 2023 Sep 26; Vol. 9 (1), pp. 353. Date of Electronic Publication: 2023 Sep 26.
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7
Akademický článek
Mitochondrial dysfunction at the crossroad of cardiovascular diseases and cancer.
Autor: Rocca C; Cellular and Molecular Cardiovascular Pathophysiology Laboratory, Department of Biology, E and E.S. (DiBEST), University of Calabria, Arcavacata di Rende, 87036, Cosenza, Italy., Soda T; Department of Health Science, University Magna Graecia of Catanzaro, 88100, Catanzaro, Italy., De Francesco EM; Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Catania, Garibaldi-Nesima Hospital, 95122, Catania, Italy., Fiorillo M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Moccia F; Laboratory of General Physiology, Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, 27100, Pavia, Italy., Viglietto G; Department of Experimental and Clinical Medicine, Magna Graecia University of Catanzaro, 88100, Catanzaro, Italy., Angelone T; Cellular and Molecular Cardiovascular Pathophysiology Laboratory, Department of Biology, E and E.S. (DiBEST), University of Calabria, Arcavacata di Rende, 87036, Cosenza, Italy. tommaso.angelone@unical.it.; National Institute of Cardiovascular Research (I.N.R.C.), 40126, Bologna, Italy. tommaso.angelone@unical.it., Amodio N; Department of Experimental and Clinical Medicine, Magna Graecia University of Catanzaro, 88100, Catanzaro, Italy. amodio@unicz.it.
Publikováno v: Journal of translational medicine [J Transl Med] 2023 Sep 19; Vol. 21 (1), pp. 635. Date of Electronic Publication: 2023 Sep 19.
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8
Publisher Correction: RAGE inhibition blunts insulin-induced oncogenic signals in breast cancer.
Autor: Muoio MG; Endocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Hospital, University of Catania, 95122, Catania, Italy.; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Pellegrino M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Rapicavoli V; Endocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Hospital, University of Catania, 95122, Catania, Italy., Talia M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Scavo G; Endocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Hospital, University of Catania, 95122, Catania, Italy., Sergi V; Endocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Hospital, University of Catania, 95122, Catania, Italy., Vella V; Endocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Hospital, University of Catania, 95122, Catania, Italy., Pettinato S; Breast Unit Breast Surgery, Garibaldi-Nesima Hospital, 95122, Catania, Italy., Galasso MG; Pathological Anatomy Unit, Garibaldi-Nesima Hospital, 95122, Catania, Italy., Lappano R; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Scordamaglia D; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Cirillo F; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Pulvirenti A; Bioinformatics Unit, Department of Clinical and Experimental Medicine, University of Catania, 95131, Catania, Italy., Rigiracciolo DC; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Via Adamello 16, 20139, Milan, Italy., Maggiolini M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy. marcello.maggiolini@unical.it., Belfiore A; Endocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Hospital, University of Catania, 95122, Catania, Italy., De Francesco EM; Endocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Hospital, University of Catania, 95122, Catania, Italy. ernestina.defrancesco@unict.it.
Publikováno v: Breast cancer research : BCR [Breast Cancer Res] 2023 Aug 10; Vol. 25 (1), pp. 94. Date of Electronic Publication: 2023 Aug 10.
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9
Akademický článek
RAGE inhibition blunts insulin-induced oncogenic signals in breast cancer.
Autor: Muoio MG; Endocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Hospital, University of Catania, 95122, Catania, Italy.; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Pellegrino M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Rapicavoli V; Endocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Hospital, University of Catania, 95122, Catania, Italy., Talia M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Scavo G; Endocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Hospital, University of Catania, 95122, Catania, Italy., Sergi V; Endocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Hospital, University of Catania, 95122, Catania, Italy., Vella V; Endocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Hospital, University of Catania, 95122, Catania, Italy., Pettinato S; Breast Unit Breast Surgery, Garibaldi-Nesima Hospital, 95122, Catania, Italy., Galasso MG; Pathological Anatomy Unit, Garibaldi-Nesima Hospital, 95122, Catania, Italy., Lappano R; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Scordamaglia D; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Cirillo F; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Pulvirenti A; Bioinformatics Unit, Department of Clinical and Experimental Medicine, University of Catania, 95131, Catania, Italy., Rigiracciolo DC; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Via Adamello 16, 20139, Milan, Italy., Maggiolini M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy. marcello.maggiolini@unical.it., Belfiore A; Endocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Hospital, University of Catania, 95122, Catania, Italy., De Francesco EM; Endocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Hospital, University of Catania, 95122, Catania, Italy. ernestina.defrancesco@unict.it.
Publikováno v: Breast cancer research : BCR [Breast Cancer Res] 2023 Jul 17; Vol. 25 (1), pp. 84. Date of Electronic Publication: 2023 Jul 17.
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10
Akademický článek
The Ephrin tyrosine kinase a3 (EphA3) is a novel mediator of RAGE-prompted motility of breast cancer cells.
Autor: Talia M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Cirillo F; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Spinelli A; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Zicarelli A; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Scordamaglia D; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Muglia L; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., De Rosis S; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Rigiracciolo DC; European Institute of Oncology IRCCS, Via Ripamonti 435, 20141, Milan, Italy., Filippelli G; Oncology Department, Hospital of Paola, 87100, Cosenza, Italy., Perrotta ID; Department of Biology, Ecology and Earth Science, University of Calabria, 87036, Rende, Italy., Davoli M; Department of Biology, Ecology and Earth Science, University of Calabria, 87036, Rende, Italy., De Rosa R; Department of Biology, Ecology and Earth Science, University of Calabria, 87036, Rende, Italy., Macirella R; Department of Biology, Ecology and Earth Science, University of Calabria, 87036, Rende, Italy., Brunelli E; Department of Biology, Ecology and Earth Science, University of Calabria, 87036, Rende, Italy., Miglietta AM; Breast and General Surgery Unit, Regional Hospital Cosenza, 87100, Cosenza, Italy., Nardo B; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy.; Breast and General Surgery Unit, Regional Hospital Cosenza, 87100, Cosenza, Italy., Tosoni D; European Institute of Oncology IRCCS, Via Ripamonti 435, 20141, Milan, Italy., Pece S; European Institute of Oncology IRCCS, Via Ripamonti 435, 20141, Milan, Italy.; Department of Oncology and Hemato-Oncology, Università Degli Studi Di Milano, 20142, Milan, Italy., De Francesco EM; Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Catania, Garibaldi-Nesima Hospital, Catania, 95122, Italy., Belfiore A; Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Catania, Garibaldi-Nesima Hospital, Catania, 95122, Italy., Maggiolini M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy. marcello.maggiolini@unical.it., Lappano R; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy. rosamaria.lappano@unical.it.
Publikováno v: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Jul 12; Vol. 42 (1), pp. 164. Date of Electronic Publication: 2023 Jul 12.
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