RAGE inhibition blunts insulin-induced oncogenic signals in breast cancer.

Autor: Muoio MG; Endocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Hospital, University of Catania, 95122, Catania, Italy.; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Pellegrino M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Rapicavoli V; Endocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Hospital, University of Catania, 95122, Catania, Italy., Talia M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Scavo G; Endocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Hospital, University of Catania, 95122, Catania, Italy., Sergi V; Endocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Hospital, University of Catania, 95122, Catania, Italy., Vella V; Endocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Hospital, University of Catania, 95122, Catania, Italy., Pettinato S; Breast Unit Breast Surgery, Garibaldi-Nesima Hospital, 95122, Catania, Italy., Galasso MG; Pathological Anatomy Unit, Garibaldi-Nesima Hospital, 95122, Catania, Italy., Lappano R; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Scordamaglia D; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Cirillo F; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Pulvirenti A; Bioinformatics Unit, Department of Clinical and Experimental Medicine, University of Catania, 95131, Catania, Italy., Rigiracciolo DC; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Via Adamello 16, 20139, Milan, Italy., Maggiolini M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy. marcello.maggiolini@unical.it., Belfiore A; Endocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Hospital, University of Catania, 95122, Catania, Italy., De Francesco EM; Endocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Hospital, University of Catania, 95122, Catania, Italy. ernestina.defrancesco@unict.it.

Publikováno v: Breast cancer research : BCR [Breast Cancer Res] 2023 Jul 17; Vol. 25 (1), pp. 84. Date of Electronic Publication: 2023 Jul 17.

The G Protein Estrogen Receptor (GPER) is involved in the resistance to the CDK4/6 inhibitor palbociclib in breast cancer.

Autor: Talia M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy., Cirillo F; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy., Scordamaglia D; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy., Di Dio M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy., Zicarelli A; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy., De Rosis S; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy., Miglietta AM; Breast and General Surgery Unit, Regional Hospital Cosenza, Cosenza, 87100, Italy., Capalbo C; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy.; Complex Operative Oncology Unit, Regional Hospital Cosenza, Cosenza, 87100, Italy., De Francesco EM; Department of Medicine and Surgery, University of Enna Kore, Enna, 94100, Italy., Belfiore A; Department of Clinical and Experimental Medicine, University of Catania, Garibaldi-Nesima Hospital, Catania, 95122, Italy., Grande F; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy., Rizzuti B; Department of Physics, CNR-NANOTEC, SS Rende (CS), University of Calabria, Rende, CS, 87036, Italy.; Institute of Biocomputation and Physics of Complex Systems (BIFI), Joint Unit GBsC-CSIC-BIFI, University of Zaragoza, Zaragoza, 50018, Spain., Occhiuzzi MA; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy., Fortino G; Department of Informatics, Modeling, Electronic, and System Engineering, University of Calabria, Rende, 87036, Italy., Guzzo A; Department of Informatics, Modeling, Electronic, and System Engineering, University of Calabria, Rende, 87036, Italy., Greco G; Department of Mathematics and Computer Science, University of Calabria, Cosenza, Italy., Maggiolini M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy. marcello.maggiolini@unical.it., Lappano R; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, 87036, Italy. rosamaria.lappano@unical.it.

Publikováno v: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2024 Jun 18; Vol. 43 (1), pp. 171. Date of Electronic Publication: 2024 Jun 18.

Mitochondrial dysfunction at the crossroad of cardiovascular diseases and cancer.

Autor: Rocca C; Cellular and Molecular Cardiovascular Pathophysiology Laboratory, Department of Biology, E and E.S. (DiBEST), University of Calabria, Arcavacata di Rende, 87036, Cosenza, Italy., Soda T; Department of Health Science, University Magna Graecia of Catanzaro, 88100, Catanzaro, Italy., De Francesco EM; Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Catania, Garibaldi-Nesima Hospital, 95122, Catania, Italy., Fiorillo M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Moccia F; Laboratory of General Physiology, Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, 27100, Pavia, Italy., Viglietto G; Department of Experimental and Clinical Medicine, Magna Graecia University of Catanzaro, 88100, Catanzaro, Italy., Angelone T; Cellular and Molecular Cardiovascular Pathophysiology Laboratory, Department of Biology, E and E.S. (DiBEST), University of Calabria, Arcavacata di Rende, 87036, Cosenza, Italy. tommaso.angelone@unical.it.; National Institute of Cardiovascular Research (I.N.R.C.), 40126, Bologna, Italy. tommaso.angelone@unical.it., Amodio N; Department of Experimental and Clinical Medicine, Magna Graecia University of Catanzaro, 88100, Catanzaro, Italy. amodio@unicz.it.

Publikováno v: Journal of translational medicine [J Transl Med] 2023 Sep 19; Vol. 21 (1), pp. 635. Date of Electronic Publication: 2023 Sep 19.

The Ephrin tyrosine kinase a3 (EphA3) is a novel mediator of RAGE-prompted motility of breast cancer cells.

Autor: Talia M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Cirillo F; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Spinelli A; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Zicarelli A; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Scordamaglia D; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Muglia L; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., De Rosis S; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy., Rigiracciolo DC; European Institute of Oncology IRCCS, Via Ripamonti 435, 20141, Milan, Italy., Filippelli G; Oncology Department, Hospital of Paola, 87100, Cosenza, Italy., Perrotta ID; Department of Biology, Ecology and Earth Science, University of Calabria, 87036, Rende, Italy., Davoli M; Department of Biology, Ecology and Earth Science, University of Calabria, 87036, Rende, Italy., De Rosa R; Department of Biology, Ecology and Earth Science, University of Calabria, 87036, Rende, Italy., Macirella R; Department of Biology, Ecology and Earth Science, University of Calabria, 87036, Rende, Italy., Brunelli E; Department of Biology, Ecology and Earth Science, University of Calabria, 87036, Rende, Italy., Miglietta AM; Breast and General Surgery Unit, Regional Hospital Cosenza, 87100, Cosenza, Italy., Nardo B; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy.; Breast and General Surgery Unit, Regional Hospital Cosenza, 87100, Cosenza, Italy., Tosoni D; European Institute of Oncology IRCCS, Via Ripamonti 435, 20141, Milan, Italy., Pece S; European Institute of Oncology IRCCS, Via Ripamonti 435, 20141, Milan, Italy.; Department of Oncology and Hemato-Oncology, Università Degli Studi Di Milano, 20142, Milan, Italy., De Francesco EM; Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Catania, Garibaldi-Nesima Hospital, Catania, 95122, Italy., Belfiore A; Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Catania, Garibaldi-Nesima Hospital, Catania, 95122, Italy., Maggiolini M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy. marcello.maggiolini@unical.it., Lappano R; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy. rosamaria.lappano@unical.it.

Publikováno v: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Jul 12; Vol. 42 (1), pp. 164. Date of Electronic Publication: 2023 Jul 12.

Editorial: A year in review: discussions in molecular and structural endocrinology.

Autor: Couvineau A; Institut National de la Santé et de la Recherche Médicale (INSERM) UMR1149/Inflammation Research Center (CRI), Université Paris Cité, Departement Hospitalo-Universitaire (DHU) UNITY, Faculty of Medicine X, Bichat, Paris, France., De Francesco EM; Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Catania, Garibaldi-Nesima Hospital, Catania, Italy.

Publikováno v: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2023 Jun 12; Vol. 14, pp. 1231470. Date of Electronic Publication: 2023 Jun 12 (Print Publication: 2023).