Cell protrusions and contractions generate long-range membrane tension propagation

Autor: De Belly, Henry, Yan, Shannon, Borja da Rocha, Hudson, Ichbiah, Sacha, Town, Jason P., Zager, Patrick J., Estrada, Dorothy C., Meyer, Kirstin, Turlier, Hervé, Bustamante, Carlos, Weiner, Orion D.

Publikováno v: In Cell 6 July 2023 186(14):3049-3061

Lymph node homeostasis and adaptation to immune challenge resolved by fibroblast network mechanics

Autor: Horsnell, Harry L, Tetley, Robert J, De Belly, Henry, Makris, Spyridon, Millward, Lindsey J, Benjamin, Agnesska C, Heeringa, Lucas A, De Winde, Charlotte M, Paluch, Ewa K, Mao, Yanlan, Acton, Sophie E

Publikováno v: Nature Immunology, 23(8), 1169-1182. Nature Publishing Group
Nature immunology, vol 23, iss 8

Emergent physical properties of tissues are not readily understood by reductionist studies of their constituent cells. Here, we show molecular signals controlling cellular, physical, and structural properties and collectively determine tissue mechani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a83e4411ab439e581915c20db42a831
https://research.vumc.nl/en/publications/2aa4a287-1797-4366-9a92-fcd7fd46fdc6

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Membrane tension orchestrates rear retraction in matrix directed cell migration

Autor: Hetmanski, Joseph H.R., de Belly, Henry, Busnelli, Ignacio, Waring, Thomas, Nair, Roshna V., Sokleva, Vanesa, Dobre, Oana, Cameron, Angus, Gauthier, Nils, Lamaze, Christophe, Swift, Joe, del Campo, Aránzazu, Starborg, Tobias, Zech, Tobias, Goetz, Jacky G., Paluch, Ewa K., Schwartz, Jean-Marc, Caswell, Patrick T.

Publikováno v: Hetmanski, J, de Belly, H, Busnelli, I, Waring, T, Nair, R V, Sokleva, V, Dobre, O, Cameron, A, Gauthier, N, Lamaze, C, Swift, J, del Campo, A, Starborg, T, Zech, T, Goetz, J G, Paluch, E K, Schwartz, J-M & Caswell, P 2019, ' Membrane tension orchestrates rear retraction in matrix directed cell migration ', Developmental cell, vol. 51, pp. 460-75 . https://doi.org/10.1016/j.devcel.2019.09.006
Developmental Cell

Summary In development, wound healing, and cancer metastasis, vertebrate cells move through 3D interstitial matrix, responding to chemical and physical guidance cues. Protrusion at the cell front has been extensively studied, but the retraction phase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c3bedef7cf01c653c5db2d8720ff935
https://doi.org/10.1016/j.devcel.2019.09.006

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