SNP of Aromatase Predict Long-term Survival and Aromatase Inhibitor Toxicity in Patients with Early Breast Cancer: A Biomarker Analysis of the GIM4 and GIM5 Trials.

Autor: Conte B; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Department of Medical Oncology, Hospital Clinic of Barcelona, Barcelona, Spain.; Universitat de Barcelona, Barcelona, Spain., Boni L; S.C. Epidemiologia Clinica, IRCCS Ospedale Policlinico San Martino, Genova, Italy., Bisagni G; Azienda unità Sanitaria Locale - IRCCS di Reggio Emilia, Reggio Emilia, Italy., Durando A; Breast Unit Ospedale S Anna, Citta' della Salute e della Scienza di Torino, Torino, Italy., Sanna G; Azienda Ospedaliera Universitaria - Sassari, Sassari, Italy., Gori S; UOC Oncologia Medica, IRCCS Ospedale Sacro Cuore Don Calabria, Negrar, Verona, Italy., Garrone O; Breast Unit, AO S. Croce e Carle Ospedale di insegnamento, Cuneo, Italy.; Medical Oncology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Milano., Tamberi S; UO Oncologia, Ospedale degli Infermi, Faenza, Italy., De Placido S; Department of Clinical Medicine and Surgery, University of Naples Federico II, Napoli, Italy., Schettini F; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Department of Medical Oncology, Hospital Clinic of Barcelona, Barcelona, Spain.; Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona, Spain., Pazzola A; Azienda Ospedaliera Universitaria - Sassari, Sassari, Italy., Ponzone R; Candiolo Cancer Institute, FPO-IRCCS, Gynecologic Oncology and Multidisciplinary Outpatient Oncology Clinic, Candiolo, Italy., Montemurro F; Candiolo Cancer Institute, FPO-IRCCS, Gynecologic Oncology and Multidisciplinary Outpatient Oncology Clinic, Candiolo, Italy., Lunardi G; Laboratorio Analisi Chimico-Cliniche, IRCCS-Ospedale Sacro Cuore Don Calabria, Negrar, Verona, Italy., Notaro R; Core Research Laboratory-ISPRO, Firenze, Italy., De Angioletti M; Core Research Laboratory-ISPRO, Firenze, Italy.; National Research Council (CNR) - ICCOM, Firenze, Italy., Turletti A; Breast Unit, ASL Citta' di Torino, Torino, Italy., Mansutti M; Department of Oncology, ASUFC Santa Maria della Misericordia, Udine, Italy., Puglisi F; Department of Medicine, University of Udine, Udine, Italy.; Depatment of Medical Oncology, Centro di Riferimento Oncologico di Aviano IRCCS, Aviano, Italy., Frassoldati A; Department of Morphology, Surgery and Experimental medicine, Clinical Oncology, St. Anna University Hospital, Ferrara, Italy., Porpiglia M; Breast Unit Ospedale S. Anna, AOU Città della Salute e della Scienza di Torino, Torino, Italy., Fabi A; Medical Oncology, IRCCS Regina Elena National Cancer Institute, Roma, Italy., Generali D; Medical Oncology, Azienda Istituti Ospitalieri di Cremona, Cremona, Italy.; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy., Scognamiglio G; Oncologia Medica, Ospedale Valduce, Como, Italy., Rossi M; SOC Oncologia, ASO SS.Antonio e Biagio, Alessandria, Italy., Brasó-Maristany F; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain., Prat A; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Department of Medical Oncology, Hospital Clinic of Barcelona, Barcelona, Spain.; Department of Clinical Medicine and Surgery, University of Naples Federico II, Napoli, Italy.; Reveal Genomics, Barcelona, Spain.; Institute of Oncology (IOB)-Hospital Quirónsalud, Barcelona, Spain., Cardinali B; Medical Oncology Department, U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genova, Italy., Piccioli P; Medical Oncology Department, U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genova, Italy., Serra M; Laboratory of Clinical and Experimental Immunology, IRCCS Istituto Giannina Gaslini, Genoa, Italy., Lastraioli S; Molecular Diagnostic Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Bighin C; Medical Oncology Department 2, IRCCS Ospedale Policlinico San Martino, Genova, Italy., Poggio F; Medical Oncology Department 2, IRCCS Ospedale Policlinico San Martino, Genova, Italy., Lambertini M; Medical Oncology Department, U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genova, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genova, Italy., Del Mastro L; Medical Oncology Department, U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genova, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genova, Italy.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2023 Dec 15; Vol. 29 (24), pp. 5217-5226.

PAROXYSMAL NOCTURNAL HEMOGLOBINURIA: CLINICAL EXPRESSION AND RESPONSE TO TREATMENT ARE MODIFIED BY A UNIQUE INTERACTION WITH CO-EXISTING GLUCOSE 6-PHOSPHATE DEHYDROGENASE DEFICIENCY

Autor: Sica, M., Pellecchia, A., Berardi, M., Gargiulo, L., Olutogun, T. A., Caocci, G., La Nasa, G., De Angioletti, M., Luzzatto, L., Notaro, R.

Publikováno v: Haematologica (Roma) 99 (2014): 386–386.
info:cnr-pdr/source/autori:Sica, M.; Pellecchia, A.; Berardi, M.; Gargiulo, L.; Olutogun, T. A.; Caocci, G.; La Nasa, G.; De Angioletti, M.; Luzzatto, L.; Notaro, R./titolo:PAROXYSMAL NOCTURNAL HEMOGLOBINURIA: CLINICAL EXPRESSION AND RESPONSE TO TREATMENT ARE MODIFIED BY A UNIQUE INTERACTION WITH CO-EXISTING GLUCOSE 6-PHOSPHATE DEHYDROGENASE DEFICIENCY/doi:/rivista:Haematologica (Roma)/anno:2014/pagina_da:386/pagina_a:386/intervallo_pagine:386–386/volume:99

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::fbf49b5e1ee55d68c3d65f74ff66fa6a
https://publications.cnr.it/doc/428372

Complement-mediated oxidative damage of red cells impairs response to eculizumab in a G6PD-deficient patient with PNH.

Autor: Sica M; Laboratory of Cancer Genetics and Gene Transfer, Core Research Laboratory-Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy., Pellecchia A; Laboratory of Cancer Genetics and Gene Transfer, Core Research Laboratory-Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy., De Angioletti M; Laboratory of Cancer Genetics and Gene Transfer, Core Research Laboratory-Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy.; Institute of Chemistry of Organometallic Compounds (ICCOM), National Council of Research, Sesto Fiorentino, Italy., Caocci G; Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.; Hematology and BMT Center, Businco Hospital, Cagliari, Italy., Nannelli C; Laboratory of Cancer Genetics and Gene Transfer, Core Research Laboratory-Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy., La Nasa G; Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.; Hematology and BMT Center, Businco Hospital, Cagliari, Italy., Luzzatto L; Muhimbili University of Health and Allied Sciences, Dar-es-Salaam, Tanzania; and.; Research Unit of Hematology, University of Florence, Florence, Italy., Notaro R; Laboratory of Cancer Genetics and Gene Transfer, Core Research Laboratory-Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy.

Publikováno v: Blood [Blood] 2020 Dec 24; Vol. 136 (26), pp. 3082-3085.

Hb Bronte or alpha93(FG5)Val>Gly: a new unstable variant of the alpha2-globin gene, associated with a mild alpha(+)-thalassemia phenotype

Autor: Lacerra G, Testa R, De Angioletti M, Schiliro G, Carestia C

Publikováno v: Hemoglobin 27 (2003): 149–159.
info:cnr-pdr/source/autori:Lacerra G, Testa R, De Angioletti M, Schiliro G, Carestia C/titolo:Hb Bronte or alpha93(FG5)Val>Gly: a new unstable variant of the alpha2-globin gene, associated with a mild alpha(+)-thalassemia phenotype/doi:/rivista:Hemoglobin/anno:2003/pagina_da:149/pagina_a:159/intervallo_pagine:149–159/volume:27

We report a new unstable variant identified in three carriers of a family from East Sicily; it was named Hb Bronte after the place from which the family originated. DNA sequencing from nucleotides -181 to +894 (alpha1) and to +884 (alpha2) revealed a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::cece405ee96a1768a47cbf042b27c998
http://www.cnr.it/prodotto/i/26421

Improvements in hematologic markers and decreases in fatigue with pegcetacoplan for patients with paroxysmal nocturnal hemoglobinuria and mild or moderate anemia (hemoglobin ≥10 g/dL) who had received eculizumab or were naive to complement inhibitors

Autor: Panse, Jens^1,2 (AUTHOR) jpanse@ukaachen.de, Daguindau, Nicolas³ (AUTHOR), Okuyama, Sonia⁴ (AUTHOR), Peffault de Latour, Régis⁵ (AUTHOR), Schafhausen, Philippe⁶ (AUTHOR), Straetmans, Nicole⁷ (AUTHOR), Al-Adhami, Mohammed⁸ (AUTHOR), Persson, Emmelie⁹ (AUTHOR), Wong, Raymond Siu Ming¹⁰ (AUTHOR)

Publikováno v: PLoS ONE. 7/29/2024, Vol. 19 Issue 7, p1-20. 20p.