Combined Targeting of NAD Biosynthesis and the NAD-dependent Transcription Factor C-terminal Binding Protein as a Promising Novel Therapy for Pancreatic Cancer.

Autor: Dcona MM; USC Norris Comprehensive Cancer Center and Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California., Chougoni KK; USC Norris Comprehensive Cancer Center and Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California., Dcona DT; USC Norris Comprehensive Cancer Center and Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California., West JL; Department of Medicinal Chemistry and Institute for Structural Biology, Drug Discovery and Development, Virginia Commonwealth University, Richmond, Virginia., Singh SJ; VCU Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia., Ellis KC; Department of Medicinal Chemistry and Institute for Structural Biology, Drug Discovery and Development, Virginia Commonwealth University, Richmond, Virginia.; VCU Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia., Grossman SR; USC Norris Comprehensive Cancer Center and Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.

Publikováno v: Cancer research communications [Cancer Res Commun] 2023 Oct 04; Vol. 3 (10), pp. 2003-2013.