Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Dazheng Wu"'
Autor:
Hui Zhou, Yueming Ma, Dazheng Wu, Xinhong Wang, Bing-Liang Ma, Changhong Wang, Rong Shi, Nengneng Cheng
Publikováno v:
Biopharmaceutics & Drug Disposition. 34:176-185
Jatrorrhizine, one of the protoberberine alkaloids derived from the plant Coptis chinensis, is expected to be developed as a new gastric prokinetic drug, but its metabolic characteristics in humans remain unknown. This study characterized the phase I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a79c8fe7db74099ff50cddb568e554ee
https://doi.org/10.1002/bdd.1835
https://doi.org/10.1002/bdd.1835
Publikováno v:
Neuropharmacology. 65:1-11
Alpha (α)-asarone is a major effective compound isolated from the Chinese medicinal herb Acorus gramineus, which is widely used in clinical practice as an antiepileptic drug; however, its mechanism of action remains unclear. In this study, we have c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dd529177ae654bb83864e7daad894a1
https://doi.org/10.1016/j.neuropharm.2012.09.001
https://doi.org/10.1016/j.neuropharm.2012.09.001
Publikováno v:
European Journal of Pharmacology. 663:74-79
This study was designed to evaluate the effect of jatrorrhizine on smooth muscle contractions isolated from rat ileum longitudinal muscles. Jatrorrhizine increased the amplitude of spontaneous contractions of ileum longitudinal muscles in concentrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::305072d8772212a48bcfadec5d5bd664
https://doi.org/10.1016/j.ejphar.2011.05.002
https://doi.org/10.1016/j.ejphar.2011.05.002
Publikováno v:
Journal of Chinese Integrative Medicine. 7:958-962
OBJECTIVE To study the relationship between the inhibitory effects of Tongxie Yaofang, a compound traditional Chinese herbal medicine, on the contraction of the colonic smooth muscle isolated from rats and calcium mobilization. METHODS By measuring t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dca70956213b5e520e26b87171e0dd9c
https://doi.org/10.3736/jcim20091009
https://doi.org/10.3736/jcim20091009
Autor:
ZhiBi Hu, DaZheng Wu
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 325:256-266
The present study evaluated the effect of rutaecarpine (Rut) on Cl(-) secretion across rat distal colonic mucosa. Basolateral application of Rut elicited an increase in short-circuit current (I(SC)) response in a concentration-dependent manner. Evide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::432d7dfddba49498b31e84f6afe8ede8
https://doi.org/10.1124/jpet.107.131961
https://doi.org/10.1124/jpet.107.131961
Publikováno v:
Cell biochemistry and biophysics. 72(1)
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has been identified as a promising anti-tumor agent against in a variety of cancers. However, gastric cancer cells are less sensitive than other cancer cells to TRAIL-induced apoptosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::453ba1c643a12e7aec2fc506bf62cdb0
https://pubmed.ncbi.nlm.nih.gov/25524636
https://pubmed.ncbi.nlm.nih.gov/25524636
Autor:
Qi Li, Hai-lian Shi, Yang Dong, Peihao Yin, Li Wang, Jianqun Xie, Aili Cao, Dazheng Wu, Guang Ji
Publikováno v:
Apoptosis : an international journal on programmed cell death. 18(11)
In the present study, we investigate the effect of curcumin, a major active component isolated from rhizomes of Curcuma longa, on the cytotoxicity of three human carcinoma cell lines (AGS, HT-29 and MGC803) in gastrointestinal tract and a normal gast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0862ced3d8503f81fa97b9cac118d10d
https://pubmed.ncbi.nlm.nih.gov/23881281
https://pubmed.ncbi.nlm.nih.gov/23881281
Autor:
Tomonori Takasaka, Akira Shimomura, Narihisa Ueda, Seiichiro Nakabayashi, Katsuhisa Ikeda, Masayuki Furukawa, Dazheng Wu
Publikováno v:
American Journal of Rhinology. 10:173-180
A muscarinic receptor in the submucosal nasal gland acinar cells controls electrolyte and fluid secretion. We investigated the pharmacological identification and the subcellular distribution of Ml receptor using a selective antagonist, pirenzepine (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d015a49931e722d219234afadbe266e8
https://doi.org/10.2500/105065896781794905
https://doi.org/10.2500/105065896781794905
Publikováno v:
Journal of Cellular Physiology. 163:204-209
In the dispersed acinar cells of the submucosal nasal gland in the guinea pig, intracellular Na+ concentration ([Na+]i) was measured with a microfluorimetric imaging method and the cytosolic indicator dye, sodium-binding benzofuran isophthalate, unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::046ed8bcffdc8c9c8bba128830892fc3
https://doi.org/10.1002/jcp.1041630123
https://doi.org/10.1002/jcp.1041630123
Autor:
Hui, Zhou, Rong, Shi, Bingliang, Ma, Yueming, Ma, Changhong, Wang, Dazheng, Wu, Xinhong, Wang, Nengneng, Cheng
Publikováno v:
Biopharmaceuticsdrug disposition. 34(3)
Jatrorrhizine, one of the protoberberine alkaloids derived from the plant Coptis chinensis, is expected to be developed as a new gastric prokinetic drug, but its metabolic characteristics in humans remain unknown. This study characterized the phase I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7a62908a3e0924ec980cc1fcfedcca64
https://pubmed.ncbi.nlm.nih.gov/23299247
https://pubmed.ncbi.nlm.nih.gov/23299247