Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Dayong Shi"'
Autor:
Xinyue Sui, Jichao Wang, Zhiqiang Zhao, Bin Liu, Miaomiao Liu, Min Liu, Cong Shi, Xinjun Feng, Yingxin Fu, Dayong Shi, Shengying Li, Qingsheng Qi, Mo Xian, Guang Zhao
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Phenolic compounds are industrially versatile chemicals, also the most ubiquitous pollutants. Recently, biosynthesis and biodegradation of phenols has attracted increasing attention, while phenols’ toxicity is a major issue. Here, we evolv
Externí odkaz:
https://doaj.org/article/afcb6834e6bd4fdcaff78c4be0a0e205
Publikováno v:
Journal of Analytical Science and Technology, Vol 11, Iss 1, Pp 1-7 (2020)
Abstract Background Bromophenol-thiosemicarbazone hybrid was a novel synthetic brominated anticancer compound with two bromine atoms. Bromophenol-thiosemicarbazone hybrid showed considerable selective inhibitory activity against PARP1 (IC50 = 29.5 nm
Externí odkaz:
https://doaj.org/article/ddebb1a4d150478e8916216e110e8bb7
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 2213-2270 (2019)
Fluorine chemistry plays an increasingly important role in pharmaceutical, agricultural, and materials industries. The incorporation of fluorine-containing groups into organic molecules can improve their chemical and physical properties, which attrac
Externí odkaz:
https://doaj.org/article/6b5a2cad17d147079549385c8f0a3171
Autor:
Jiajia Dai, Yiting Zhang, Yanan Gao, Xiaoyi Bai, Fang Liu, Shuo Li, Yanyan Yu, Wenpeng Hu, Ting Shi, Dayong Shi, Xiangqian Li
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3497 (2022)
Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) is a non-receptor protein tyrosine phosphatase (PTP) encoded by the PTPN11 gene, which is involved in the RAS/MAPK cell signaling transduction process. SHP2 has been shown to cont
Externí odkaz:
https://doaj.org/article/612b57746d114741bae4ecf9451ae822
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
A highly selective copper-catalyzed trifluoromethylation of indoles is reported with the assistance of a removable directing group. This protocol provides an easy and rapid method to various 2-position-selective trifluoromethylated heteroarenes inclu
Externí odkaz:
https://doaj.org/article/cbeaf148affc4ba094fdb4decfc62c5a
Publikováno v:
Marine Drugs, Vol 18, Iss 9, p 469 (2020)
Gut microbiota has a critical role in metabolic diseases, including type 2 diabetes mellitus (T2DM). 3-bromo-4,5-bis(2,3-dibromo-4,5-dihydroxybenzyl)-1,2-benzenediol (BDB) is a natural bromophenol isolated from marine red alga Rhodomela confervoides.
Externí odkaz:
https://doaj.org/article/20284d948683492795d0ae61c7aebdf2
Publikováno v:
Marine Drugs, Vol 18, Iss 5, p 267 (2020)
3-bromo-4,5-Bis(2,3-dibromo-4,5-dihydroxybenzyl)-1,2-benzenediol (CYC31) is a bromophenol protein tyrosine phosphatase 1B (PTP1B) inhibitor isolated from the red alga Rhodomela confervoides. Here, the effect of CYC31 on the insulin signaling and fatt
Externí odkaz:
https://doaj.org/article/fb07730772ff40af94a32af8db2a9b84
Autor:
Jiajia Zhang, Jiajia Dai, Qingxuan Zheng, Shuju Guo, Yanyan Yu, Wenpeng Hu, Yanan Gao, Dayong Shi
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 1038 (2020)
Triple negative breast cancer (TNBC) is the most aggressive cancer in women, and despite improved treatments, it remains a major cause of morbidity and mortality. We and others have demonstrated that different hybrid compounds targeting PARP/MAPK or
Externí odkaz:
https://doaj.org/article/0187c2e2e76c44148e01c510bedb95e2
Autor:
Jiao Luo, Ning Wu, Bo Jiang, Lijun Wang, Shuaiyu Wang, Xiangqian Li, Baocheng Wang, Changhui Wang, Dayong Shi
Publikováno v:
Marine Drugs, Vol 13, Iss 7, Pp 4452-4469 (2015)
3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-isopropoxymethyl benzyl)benzene-1,2-diol (HPN) is a bromophenol derivative from the marine red alga Rhodomela confervoides. We have previously found that HPN exerted an anti-hyperglycemic property in db/db mouse
Externí odkaz:
https://doaj.org/article/af9065770ae04b61a83c0ee1835424d7
Autor:
Shuaiyu Wang, Li-Jun Wang, Bo Jiang, Ning Wu, Xiangqian Li, Shaofang Liu, Jiao Luo, Dayong Shi
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 6, Pp 13548-13560 (2015)
Bis-(2,3-dibromo-4,5-dihydroxy-phenyl)-methane (BDDPM) is a bromophenol first isolated from Rhodomelaceae confervoides. Our previous studies showed that BDDPM exerts PTP1B-inhibiting activity and anti-cancer activity against a wide range of tumor cel
Externí odkaz:
https://doaj.org/article/fb9f2c6361dd4f52a3a5654cf61b22d2