Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Dayne Beccano-Kelly"'
Autor:
Quyen B. Do, Humaira Noor, Ricardo Marquez-Gomez, Kaitlyn M. L. Cramb, Bryan Ng, Ajantha Abbey, Naroa Ibarra-Aizpurua, Maria Claudia Caiazza, Parnaz Sharifi, Charmaine Lang, Dayne Beccano-Kelly, Jimena Baleriola, Nora Bengoa-Vergniory, Richard Wade-Martins
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-15 (2024)
Abstract Understanding medium spiny neuron (MSN) physiology is essential to understand motor impairments in Parkinson’s disease (PD) given the architecture of the basal ganglia. Here, we developed a custom three-chambered microfluidic platform and
Externí odkaz:
https://doaj.org/article/97680562b37f462c955fb032be5c6fe7
Autor:
Julia Benkert, Simon Hess, Shoumik Roy, Dayne Beccano-Kelly, Nicole Wiederspohn, Johanna Duda, Carsten Simons, Komal Patil, Aisylu Gaifullina, Nadja Mannal, Elena Dragicevic, Desirée Spaich, Sonja Müller, Julia Nemeth, Helene Hollmann, Nora Deuter, Yassine Mousba, Christian Kubisch, Christina Poetschke, Joerg Striessnig, Olaf Pongs, Toni Schneider, Richard Wade-Martins, Sandip Patel, Rosanna Parlato, Tobias Frank, Peter Kloppenburg, Birgit Liss
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Voltage-gated Ca2+ channels are thought to contribute to neurodegeneration of dopaminergic neurons. Here the authors find that the R-type channel Cav2.3 in substantia nigra dopaminergic neurons may contribute to neurodegeneration in a model of Parkin
Externí odkaz:
https://doaj.org/article/8271fb3221094175818e53f6966e1e51
Autor:
Christa Überbacher, Julia Obergasteiger, Mattia Volta, Serena Venezia, Stefan Müller, Isabella Pesce, Sara Pizzi, Giulia Lamonaca, Anne Picard, Giada Cattelan, Giorgio Malpeli, Michele Zoli, Dayne Beccano-Kelly, Rowan Flynn, Richard Wade-Martins, Peter P. Pramstaller, Andrew A. Hicks, Sally A. Cowley, Corrado Corti
Publikováno v:
Stem Cell Research, Vol 41, Iss , Pp - (2019)
Human induced pluripotent stem cells (hiPSCs) have become indispensable for disease modelling. They are an important resource to access patient cells harbouring disease-causing mutations. Derivation of midbrain dopaminergic (DAergic) neurons from hiP
Externí odkaz:
https://doaj.org/article/6e76bf2d5a2e4e7c95a3d47a59363d4e
Autor:
Dayne Beccano-Kelly, Jenni Harvey
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2012 (2012)
It is well established that the hormone leptin circulates in the plasma in amounts proportional to body fat content and it regulates food intake and body weight via its actions in the hypothalamus. However, numerous studies have shown that leptin rec
Externí odkaz:
https://doaj.org/article/7d6a8aeda56b4b16876b3915e0437aee
Autor:
Quyen B. Do, Bryan Ng, Ricardo Marquez Gomez, Dayne Beccano-Kelly, Naroa Ibarra-Aizpura, Maria-Claudia Caiazza, Charmaine Lang, Jimena Baleriola, Nora Bengoa-Vergniory, Richard Wade-Martins
Understanding medium spiny neuron (MSN) physiology is essential to understand motor impairments in Parkinson’s disease (PD) given the architecture of the basal ganglia. Here, we developed a custom three-chamber microfluidic platform and established
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f39afc392ce2c5281b0f39b518bc6ee2
https://doi.org/10.1101/2023.03.01.530566
https://doi.org/10.1101/2023.03.01.530566
Publikováno v:
Brain.
Parkinson’s disease is the second most common neurodegenerative disease and yet the early pathophysiological events of the condition and sequences of dysfunction remain unclear. The loss of dopaminergic neurons and reduced levels of striatal dopami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0253d227801dcdfa6ced1414c15fa058
https://doi.org/10.1093/brain/awad064
https://doi.org/10.1093/brain/awad064
Autor:
Bryan Ng, Jane Vowles, Dayne Beccano-Kelly, M Irina Stefana, Darragh P. O’Brien, Nora Bengoa-Vergniory, Feodora Betherat, Ajantha Abey, Philippa Carling, Peter Kilfeather, John A. Todd, Tara M. Caffrey, Natalie Connor-Robson, Sally A. Cowley, Richard Wade-Martins
BackgroundAlzheimer’s disease (AD) is an age-related neurodegenerative condition and the most common type of dementia, characterised by pathological accumulation of extracellular plaques and intracellular neurofibrillary tangles that mainly consist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed0da9d611bbca4f905fdb8b671f8d13
https://doi.org/10.1101/2022.12.23.521772
https://doi.org/10.1101/2022.12.23.521772
Autor:
Dayne Beccano-Kelly, Alastair J. Noyce, Sara Bandres-Ciga, Artur Francisco Schumacher Schuh, Yared Zenebe, Bernadette Siddiqi
Publikováno v:
Autumn 2021.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::437ea4473cb2626f5878de03d33bcfb8
https://doi.org/10.36866/123.32
https://doi.org/10.36866/123.32
Autor:
Chelsie A Kadgien, Naila Kuhlmann, Dayne Beccano-Kelly, Stefano Cataldi, Austen J. Milnerwood, Sarah E MacIsaac, Mattia Volta, Jesse Fox, Sarah A Paschall, Emma Mitchell, Igor Tatarnikov, Heather L. Melrose, Sabrina Bergeron, Jaskaran Khinda, Matthew J. Farrer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33329d81fe5dd39cb3d8176d0515169a
https://doi.org/10.7554/elife.28377.016
https://doi.org/10.7554/elife.28377.016
Autor:
Shernaz X. Bamji, G. Stefano Brigidi, Dayne Beccano-Kelly, Yu Sun, Stephanie L. Borgland, Kimberley A Pitman, Mahsan Mobasser, Austen J. Milnerwood
Publikováno v:
Nature neuroscience
Synaptic cadherin adhesion complexes are known to be key regulators of synapse plasticity. However, the molecular mechanisms that coordinate activity-induced modifications in cadherin localization and adhesion and the subsequent changes in synapse mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35e4eedee0e1e6f5fb2a27d2703a24b8
http://europepmc.org/articles/PMC5025286
http://europepmc.org/articles/PMC5025286