Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Dayna Tracy"'
Autor:
Kathryn D. Tuttle, Katherine A. Waugh, Paula Araya, Ross Minter, David J. Orlicky, Michael Ludwig, Zdenek Andrysik, Matthew A. Burchill, Beth A.J. Tamburini, Colin Sempeck, Keith Smith, Ross Granrath, Dayna Tracy, Jessica Baxter, Joaquin M. Espinosa, Kelly D. Sullivan
Publikováno v:
Cell Reports, Vol 33, Iss 7, Pp 108407- (2020)
Summary: Individuals with Down syndrome (DS; trisomy 21) display hyperactivation of interferon (IFN) signaling and chronic inflammation, which could potentially be explained by the extra copy of four IFN receptor (IFNR) genes encoded on chromosome 21
Externí odkaz:
https://doaj.org/article/8fd7536ebdba4b9c98e33eeca1e00d4f
Autor:
Katherine A. Waugh, Ross Minter, Jessica Baxter, Congwu Chi, Kathryn D. Tuttle, Neetha P. Eduthan, Matthew D. Galbraith, Kohl T. Kinning, Zdenek Andrysik, Paula Araya, Hannah Dougherty, Lauren N. Dunn, Michael Ludwig, Kyndal A. Schade, Dayna Tracy, Keith P. Smith, Ross E. Granrath, Nicolas Busquet, Santosh Khanal, Ryan D. Anderson, Liza L. Cox, Belinda Enriquez Estrada, Angela L. Rachubinski, Hannah R. Lyford, Eleanor C. Britton, David J. Orlicky, Jennifer L. Matsuda, Kunhua Song, Timothy C. Cox, Kelly D. Sullivan, Joaquin M. Espinosa
Trisomy 21 causes Down syndrome, a condition characterized by cognitive impairments, immune dysregulation, and atypical morphogenesis. Using whole blood transcriptome analysis, we demonstrate that specific overexpression of four interferon receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0537897f7410b5176b3650f94e662bc
https://doi.org/10.1101/2022.02.03.478982
https://doi.org/10.1101/2022.02.03.478982
Autor:
Paula Araya, Keith P Smith, Kelly D. Sullivan, Zdenek Andrysik, Beth A. Jirón Tamburini, Dayna Tracy, Katherine A. Waugh, Kathryn D. Tuttle, Ross E Granrath, Joaquín M. Espinosa, Colin Sempeck, Michael Ludwig, Ross Minter, Matthew A. Burchill, Jessica Baxter, David J. Orlicky
Publikováno v:
Cell Rep
Cell Reports
Cell Reports, Vol 33, Iss 7, Pp 108407-(2020)
Cell Reports
Cell Reports, Vol 33, Iss 7, Pp 108407-(2020)
Summary: Individuals with Down syndrome (DS; trisomy 21) display hyperactivation of interferon (IFN) signaling and chronic inflammation, which could potentially be explained by the extra copy of four IFN receptor (IFNR) genes encoded on chromosome 21
Autor:
Jennifer C. Whitesell, Rachel S. Friedman, Kristen E. Dew, Jordan Jacobelli, Erika Rodriguez, Robin S. Lindsay, Dayna Tracy, Seth F. Yannacone, Adam M. Sandor, Brittany N. Basta
Publikováno v:
The Journal of experimental medicine. 218(10)
Understanding mechanisms of immune regulation is key to developing immunotherapies for autoimmunity and cancer. We examined the role of mononuclear phagocytes during peripheral T cell regulation in type 1 diabetes and melanoma. MERTK expression and a
Publikováno v:
The Journal of Immunology. 196:49.5-49.5
Type 1 diabetes (T1D) is a T cell mediated autoimmune disease that results from destruction of the beta cells in the pancreatic islets. Curiously, infiltrated islets can continue to contain beta cells for years following disease onset, suggesting a t