Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Dayna R. Loyd"'
Autor:
Dayna R. Loyd, Anne Z. Murphy
Publikováno v:
Neural Plasticity, Vol 2009 (2009)
Externí odkaz:
https://doaj.org/article/c7502d7695184be39d98378cadca0a82
Publikováno v:
Pain. 152:2267-2276
Peripheral serotonin (5HT) has been implicated in migraine and temporomandibular pain disorders in humans and animal models and yet the mechanism(s) by which 5HT evokes pain remains unclear. Trigeminal pain can be triggered by activation of the trans
Publikováno v:
The Journal of Neuroscience. 28:14007-14017
Opioid-based narcotics are the most widely prescribed therapeutic agent for the alleviation of persistent pain; however, it is becoming increasingly clear that morphine is significantly less potent in women compared with men. Morphine primarily binds
Publikováno v:
European Journal of Neuroscience. 27:1517-1524
The midbrain periaqueductal gray (PAG) and its descending projections to the rostral ventromedial medulla (RVM) provides an essential neural circuit for the antinociceptive effects of opiates, and has been implicated in the development of tolerance t
Autor:
Anne Z. Murphy, Dayna R. Loyd
Publikováno v:
The Journal of Comparative Neurology. 496:723-738
Previous studies have demonstrated that morphine, administered systemically or directly into the periaqueductal gray (PAG), produces a significantly greater degree of antinociception in males in comparison with females. Because the midbrain PAG and i
Publikováno v:
Developmental Psychobiology. 47:158-165
We tested the effects of exposure to different doses of lead acetate (either 0, 25, 100, or 400 ppm) on the development of aggressive behavior in male golden hamsters. Pups were tested for offensive responses across puberty, as they were maturing fro
Autor:
Anne Z. Murphy, Dayna R. Loyd
Publikováno v:
Experimental neurology. 259
The influence of sex has been neglected in clinical studies on pain and analgesia, with the vast majority of research conducted exclusively in males. However, both preclinical and clinical studies indicate that males and females differ in both the an
Autor:
Marcie Fowler, Laura L. McGhee, Bopaiah P. Cheppudira, David Devore, John L. Clifford, Lawrence N. Petz, Alberto Mares, Dayna R. Loyd, Angie Greer
Publikováno v:
Expert opinion on investigational drugs. 22(10)
Managing burn injury-associated pain and wounds is a major unresolved clinical problem. Opioids, nonsteroidal antiinflammatory drugs (NSAIDs), antidepressants and anticonvulsants remain the most common forms of analgesic therapy to treat burn patient
Autor:
Joseph Novak, Helen M. Arizpe, Dayna R. Loyd, Terry M. Slater, Thomas H. Garza, Marcie Fowler, John L. Clifford, Lawrence N. Petz
Publikováno v:
Burns : journal of the International Society for Burn Injuries. 40(4)
Opioid-related side effects are problematic for burn patients. Dual mechanism therapeutics targeting opioid and non-opioid mechanisms may have reduced side effects with similar analgesic efficacy. Tramadol combines mu opioid receptor agonism with nor