Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Daylin Morgan"'
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Intratumor heterogeneity reduces treatment efficacy and complicates our understanding of tumor progression and there is a pressing need to understand the functions of heterogeneous tumor cell subpopulations within a tumor, yet systems to stu
Externí odkaz:
https://doaj.org/article/85c7e24e22ec4a628cda0b01fa8ec47f
Publikováno v:
Cancer Research. 83:122-122
Solid tumors such as triple-negative breast cancer (TNBC) have characteristically high rates of aneuploidy and polyploidy. Chromosome-level aneuploidies are known to arise through errors in cytokinesis, but many of the mechanisms which drive large-sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2462291202f814279886db3f2cf431c5
https://doi.org/10.1158/1538-7445.am2023-122
https://doi.org/10.1158/1538-7445.am2023-122
Autor:
Sreedevi Raman, Nicholas Brookhouser, Daylin Morgan, David A. Brafman, Tanner Henson, Toan Nguyen, Gayathri Srinivasan, Joshua Cutts
Publikováno v:
ACS Biomaterials Science & Engineering
Astrocytes comprise the most abundant cell type in the central nervous system (CNS) and play critical roles in maintaining neural tissue homeostasis. In addition, astrocyte dysfunction and death has been implicated in numerous neurological disorders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee78abea4215a083850ead6305fb6e50
http://europepmc.org/articles/PMC7284803
http://europepmc.org/articles/PMC7284803
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2394
The ability to track and isolate unique cell lineages from large heterogeneous populations increases the resolution at which cellular processes can be understood under normal and pathogenic states beyond snapshots obtained from single-cell RNA sequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f59a1d5e142bd46a5261c990d08c958
https://pubmed.ncbi.nlm.nih.gov/35094325
https://pubmed.ncbi.nlm.nih.gov/35094325
Publikováno v:
Methods in Molecular Biology ISBN: 9781071618103
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5996995620adaebb6324eac3843fa544
https://doi.org/10.1007/978-1-0716-1811-0_8
https://doi.org/10.1007/978-1-0716-1811-0_8
Publikováno v:
Curr Opin Biomed Eng
Tumors are comprised of dynamic, heterogenous cell populations characterized by numerous genetic and nongenetic alterations that accumulate and change with disease progression and treatment. Retrospective analyses of tumor evolution have relied on th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b62433c548b5b0d33ceaca8b48eb5a30
https://europepmc.org/articles/PMC8658740/
https://europepmc.org/articles/PMC8658740/
Autor:
Thomas E. Yankeelov, Grant Howard, Angela M. Jarrett, Russell E. Durrett, Aziz Al'Khafaji, Amy Brock, Eric Brenner, William Mo, Kaitlyn E. Johnson, Andrea Gardner, Daylin Morgan, Eduardo D. Sontag
Publikováno v:
Phys Biol
A significant challenge in the field of biomedicine is the development of methods to integrate the multitude of dispersed data sets into comprehensive frameworks to be used to generate optimal clinical decisions. Recent technological advances in sing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deaa2d85dc1d7d7b7934c84448af7ce5
https://europepmc.org/articles/PMC8156495/
https://europepmc.org/articles/PMC8156495/
Autor:
Grant Howard, Angela M. Jarrett, Eric Brenner, Amy Brock, Aziz Al'Khafaji, Thomas E. Yankeelov, Daylin Morgan, William Mo, Kaitlyn E. Johnson, Russell E. Durrett, Andrea Gardner, Eduardo D. Sontag
SummaryA significant challenge in the field of biomedicine is the development of methods to integrate the multitude of dispersed data sets into comprehensive frameworks to be used to generate optimal clinical decisions. Recent technological advances
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e320779093658af03082df955820ea
Publikováno v:
Acta Biomater
Human pluripotent stem cell derived neural progenitor cells (hNPCs) have the unique properties of long-term in vitro expansion as well as differentiation into the various neurons and supporting cell types of the central nervous system (CNS). Because
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bcaf2153dc07aa407de2fd06d88c8f3
https://doi.org/10.1016/j.actbio.2018.05.008
https://doi.org/10.1016/j.actbio.2018.05.008
Autor:
Catherine Gutierrez, Eric Brenner, Daylin Morgan, Catherine J. Wu, Aziz Al'Khafaji, Amy Brock
Publikováno v:
Cancer Research. 80:PO-097
The immense evolutionary capacity of cancer poses major challenges to current therapeutic efforts, and results from the vast clonal heterogeneity and ability of individual cancer cells to adapt to diverse selective pressures. More complete mechanisti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::119e286aabfca9f0f8415978baa6d358
https://doi.org/10.1158/1538-7445.tumhet2020-po-097
https://doi.org/10.1158/1538-7445.tumhet2020-po-097