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Akademický článek

Hydrogel-based microfluidic device with multiplexed 3D in vitro cell culture

Autor: Allison Clancy, Dayi Chen, Joseph Bruns, Jahnavi Nadella, Samuel Stealey, Yanjia Zhang, Aaron Timperman, Silviya P. Zustiak

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)

Abstract Microfluidic devices that combine an extracellular matrix environment, cells, and physiologically relevant perfusion, are advantageous as cell culture platforms. We developed a hydrogel-based, microfluidic cell culture platform by loading po

Externí odkaz: https://doaj.org/article/7e4a80b2fe864a4697cc7fe8685a6d34

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Akademický článek

Corrigendum: Dopamine homeostasis imbalance and dopamine receptors-mediated AC/cAMP/PKA pathway activation are involved in aconitine-induced neurological impairment in zebrafish and SH-SY5Y cells

Autor: Jie Zhou, Cheng Peng, Qiuju Li, Xiaoyu Yan, Liang Yang, Mengting Li, Xiaoyu Cao, Xiaofang Xie, Dayi Chen, Chaolong Rao, Sizhou Huang, Fu Peng, Xiaoqi Pan

Publikováno v: Frontiers in Pharmacology, Vol 14 (2023)

Externí odkaz: https://doaj.org/article/fb5b590971e34fd4be34d4f5e434bbde

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Akademický článek

Current advances on the phytochemical composition, pharmacologic effects, toxicology, and product development of Phyllanthi Fructus

Autor: Xiaoyu Yan, Qiuju Li, Lin Jing, Shuangyue Wu, Wei Duan, Yan Chen, Dayi Chen, Xiaoqi Pan

Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)

Phyllanthi Fructus (PF), the edible fruits of Phyllanthus emblica L., serves as an important resource for some health products, foods and drugs due to its high safety and sufficient nutritional value. In recent years, in vivo and in vitro experiments

Externí odkaz: https://doaj.org/article/4d32c03923b1484abf3cbd850377e46f

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Akademický článek

Dopamine Homeostasis Imbalance and Dopamine Receptors-Mediated AC/cAMP/PKA Pathway Activation are Involved in Aconitine-Induced Neurological Impairment in Zebrafish and SH-SY5Y Cells

Autor: Jie Zhou, Cheng Peng, Qiuju Li, Xiaoyu Yan, Liang Yang, Mengting Li, Xiaoyu Cao, Xiaofang Xie, Dayi Chen, Chaolong Rao, Sizhou Huang, Fu Peng, Xiaoqi Pan

Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)

Aconitine is one of the main bioactive and toxic ingredients of Aconitum species. Increasingly, aconitine has been reported to induce neurotoxicity. However, whether aconitine has effects on the dopaminergic nervous system remains unclear. In this st

Externí odkaz: https://doaj.org/article/9fcc5a3a13804b81a9fdd5e586ea986f

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Akademický článek

Risk Compounds, Preclinical Toxicity Evaluation, and Potential Mechanisms of Chinese Materia Medica–Induced Cardiotoxicity

Autor: Jie Zhou, Fu Peng, Xiaoyu Cao, Xiaofang Xie, Dayi Chen, Lian Yang, Chaolong Rao, Cheng Peng, Xiaoqi Pan

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

Chinese materia medica (CMM) has been applied for the prevention and treatment of diseases for thousands of years. However, arrhythmia, myocardial ischemia, heart failure, and other cardiac adverse reactions during CMM application were gradually repo

Externí odkaz: https://doaj.org/article/8b5c25b56719429fa9dab7286e86447e

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Analyte Enrichment via Ion Concentration Polarization with Hydrogel Plugs Polymerized in PDMS Microchannels by a Facile and Comprehensive Method for Improved Polymerization

Autor: Dayi Chen, Aaron T. Timperman

Publikováno v: Analytical chemistry. 94(45)

Hydrogels are incorporated into microfluidic devices to provide enhanced functionality by enabling processes such as enzyme immobilization, sample enrichment, and ionic current rectification. However, in the microfluidic devices with the commonly use

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba53afd689abdb11b29f7bdfd052c8bf
https://pubmed.ncbi.nlm.nih.gov/36318671

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Acrylamide induces the activation of BV2 microglial cells through TLR2/4-mediated LRRK2-NFATc2 signaling cascade

Autor: Xiaoyu Yan, Qiuju Li, Shuangyue Wu, Jie Liang, Yuanyuan Li, Tingting Zhang, Dayi Chen, Xiaoqi Pan

Publikováno v: Food and Chemical Toxicology. 176:113775

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::585fba40150b4336d34eae027a3299a3
https://doi.org/10.1016/j.fct.2023.113775

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Ameliorated effect of Lactobacillus plantarum SCS2 on the oxidative stress in HepG2 cells induced by AFB1

Autor: Lan LONG, Xiao MENG, Jiayi SUN, Lin JING, Dayi CHEN, Rong YU

Publikováno v: Food Science and Technology v.42 2022
Food Science and Technology (Campinas)
Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA)
instacron:SBCTA
Food Science and Technology, Volume: 42, Article number: e16522, Published: 02 MAY 2022

Aflatoxin B1 (AFB1), a widespread mycotoxin found in food, poses a significant threat to the food industry and production. The primary target of AFB1 is the liver. Probiotic-mediated antitoxicity has been proposed to overcome aflatoxin toxicity. In t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35ad5c9b346c886e16386273b61a50da
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612022000101104

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