Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Dayananda Siddappa"'
Autor:
Dayananda Siddappa, Élaine Beaulieu, Nicolas Gévry, Philippe P Roux, Vilceu Bordignon, Raj Duggavathi
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119387 (2015)
Mitogen-activated protein kinase 3/1 (Mapk3/1) pathway is critical for LH signal transduction during ovulation. However, the mechanisms remain incompletely understood. We hypothesized that Mapk pathway regulates ovulation through transcriptional regu
Externí odkaz:
https://doaj.org/article/6ccfef20ac934433a4f7e74f0d4ad913
Autor:
Maya C. Poffenberger, Jennifer L. Bishop, Ryan J. Blackler, Kevin G. Haworth, Steven Booth, Shalla Hanson, Jeff R. Proctor, I-Ting Shao, Nichole K. Escalante, Dayananda Siddappa, Joel Smith, Gursev Anmole, Saki Konomura, Nicholas A. Dawson, Sifa Arrafi, Desmond Lau, Gerry Rowse, Rupert H. Davies, Thomas Spreter von Kreudenstein
Publikováno v:
Cancer Research. 83:2935-2935
IL-12 is a pleiotropic cytokine that potently stimulates anti-tumor cytotoxic T and NK cell mediated immunity. Recombinant IL-12 reduces tumor growth in multiple mouse models, but its therapeutic application has been limited by severe toxicities. Pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ce2847d4ba0b7753f41e7b03785e454
https://doi.org/10.1158/1538-7445.am2023-2935
https://doi.org/10.1158/1538-7445.am2023-2935
Autor:
Sam Lawn, Andrea Hernandez Rojas, Raffaele Colombo, Dayananda Siddappa, Jodi Wong, Kaylee Wu, Vincent Fung, Dunja Urosev, Luying Yang, Jamie R. Rich, Stuart D. Barnscher
Publikováno v:
Cancer Research. 83:2641-2641
Background: Folate Receptor alpha (FRa) is a validated cell surface cancer target that is prevalently expressed in multiple cancers with high unmet need, including ovarian cancer and other gynecological cancers, while exhibiting minimal expression in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f860aaaf7b7696930d6eef0971fe49e3
https://doi.org/10.1158/1538-7445.am2023-2641
https://doi.org/10.1158/1538-7445.am2023-2641
Autor:
Philippe P. Roux, Dayananda Siddappa, Vilceu Bordignon, Yasmin Schuermann, Ejimedo Madogwe, Raj Duggavathi
Publikováno v:
Reproduction. 161:183-193
Abolition of the LH-induced ERK1/2 pathway leads to dramatic changes in gene expression in granulosa cells, subsequently abrogating ovulation. Here we explored whether sustained ERK1/2 signaling beyond immediate-early hours of the LH surge is importa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a734a8f08937bc691a6160bcdc70a021
https://doi.org/10.1530/rep-20-0087
https://doi.org/10.1530/rep-20-0087
Publikováno v:
Molecular Reproduction and Development. 85:316-324
Successful ovulation requires the actions of gonadotropins along with those mediated by growth factors binding to their receptor tyrosine kinases (RTKs). There are several growth factors such as epidermal growth factor family ligands and interleukins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aae331ec23f3f6bdc16c8cf3ff061f56
https://doi.org/10.1002/mrd.22966
https://doi.org/10.1002/mrd.22966
Autor:
Monique Tomazele Rovani, Werner G. Glanzner, Janduí Escarião da Nóbrega, Paulo Bayard Dias Gonçalves, Dayananda Siddappa, Gustavo Freitas Ilha, Vilceu Bordignon, Alfredo Q. Antoniazzi, Raj Duggavathi, Bernardo Garziera Gasperin
Publikováno v:
Molecular Reproduction and Development. 84:486-494
Prostaglandin F2α (PGF) induces the precipitous loss of steroidogenic capabilities and cellular death in the corpus luteum of many species, yet the molecular mechanisms underlying this event are not completely understood. Signal transducer and activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4af241498b183efc0aa905db39de65d6
https://doi.org/10.1002/mrd.22798
https://doi.org/10.1002/mrd.22798
Autor:
Dana Praslickova, Melissa Pansera, Dayananda Siddappa, Isabelle Ménard, Luis B. Agellon, Yasmin Schuermann, Raj Duggavathi
Publikováno v:
Journal of Reproduction and Development. 61:237-240
The fatty acid binding protein 6 (Fabp6) is commonly regarded as a bile acid binding protein found in the distal portion of the small intestine and has been shown to be important in maintaining bile acid homeostasis. Previous studies have also report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb731dfc7fca3c15962599cb8405377b
https://doi.org/10.1262/jrd.2014-139
https://doi.org/10.1262/jrd.2014-139
Autor:
Dayananda Siddappa, Vilceu Bordignon, Anitha Kalaiselvanraja, Raj Duggavathi, Philippe P. Roux, Bernardo Garziera Gasperin, Lisa Dupuis
Publikováno v:
Molecular Reproduction and Development. 81:655-665
SUMMARY A complex network of endocrine/paracrine signals regulates granulosa-cell function inovarianfollicles.Mechanistictargetofrapamycin(MTOR)hasrecentlyemergedas a master intracellular integrator of extracellular signals and nutrient availability.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17fd4af34b4e52a5071c18c4979bf521
https://doi.org/10.1002/mrd.22333
https://doi.org/10.1002/mrd.22333
Autor:
Yasmin Schuermann, Anitha Kalaiselvanraja, Vilceu Bordignon, Raj Duggavathi, Tamara R. Cohen, Melissa Pansera, Lisa Dupuis, Dayananda Siddappa
Publikováno v:
REPRODUCTION. 147:221-229
Leptin is an important hormone influencing reproductive function. However, the mechanisms underpinning the role of leptin in the regulation of reproduction remain to be completely deciphered. In this study, our objective is to understand the mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b74f1643335bd752e1c7e1a0683ccc
https://doi.org/10.1530/rep-13-0356
https://doi.org/10.1530/rep-13-0356
Autor:
Dayananda, Siddappa, Anitha, Kalaiselvanraja, Vilceu, Bordignon, Lisa, Dupuis, Bernardo G, Gasperin, Philippe P, Roux, Raj, Duggavathi
Publikováno v:
Molecular reproduction and development. 81(7)
A complex network of endocrine/paracrine signals regulates granulosa-cell function in ovarian follicles. Mechanistic target of rapamycin (MTOR) has recently emerged as a master intracellular integrator of extracellular signals and nutrient availabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a014e94e763fd48ae116e132475074ed
https://pubmed.ncbi.nlm.nih.gov/24753052
https://pubmed.ncbi.nlm.nih.gov/24753052