Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Dayan Knox"'
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 15 (2021)
Post-traumatic stress disorder (PTSD) is a debilitating psychiatric disorder with a high economic burden. Two risk factors for increasing the chances of developing PTSD are sex (being female) and early life stress. These risk factors suggest that ear
Externí odkaz:
https://doaj.org/article/7f1b5c6fa8784616ad589b9bc56b59c2
Autor:
Chantelle Ferland-Beckham, Lauren E. Chaby, Nikolaos P. Daskalakis, Dayan Knox, Israel Liberzon, Miranda M. Lim, Christa McIntyre, Shane A. Perrine, Victoria B. Risbrough, Esther L. Sabban, Andreas Jeromin, Magali Haas
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 15 (2021)
Posttraumatic stress disorder (PTSD) is a mental health condition triggered by experiencing or witnessing a terrifying event that can lead to lifelong burden that increases mortality and adverse health outcomes. Yet, no new treatments have reached th
Externí odkaz:
https://doaj.org/article/a73e5ff5de624eb29f24db7df0924efc
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0205144 (2018)
Glucocorticoid receptors (GRs) shuttle from the cytoplasm (cy) to the nucleus (nu) when bound with glucocorticoids (i.e. GR internalization) and alter transcriptional activity. GR activation within the fear circuit has been implicated in fear memory
Externí odkaz:
https://doaj.org/article/23d1be95d25e478f8b96ba31f242804a
Autor:
Matthew Biddle, Dayan Knox
Publikováno v:
Psychopharmacology. 240:1049-1061
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8207f40d68324f4e4aff3320931e8713
https://doi.org/10.1007/s00213-023-06342-6
https://doi.org/10.1007/s00213-023-06342-6
Autor:
Dayan Knox, Negin Mohammadmirzaei, Matthew Biddle, Bailey Collins, Xuezhu Cai, Praveen Kulkarni, Khan Hekmatyar, Donna Wood, Sushma Boyapati, Michelle Barth
Publikováno v:
Biological Psychiatry. 93:S84
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bc6f52e956596bdb83bbbd4f8479fef
https://doi.org/10.1016/j.biopsych.2023.02.219
https://doi.org/10.1016/j.biopsych.2023.02.219
Autor:
Negin Mohammadmirzaei, Matt Biddle, Abigail Farkash, Brianna Shultz, Marisa Chamness, Rebecca Della Valle, Dayan Knox, Emily Moulton
Publikováno v:
International Journal of Neuropsychopharmacology
Background A core symptom of posttraumatic stress disorder is persistent fear memory, which can be defined as fear memory that is resistant to updating, inhibition, or extinction. posttraumatic stress disorder emerges after traumatic stress exposure,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6693e878661dca1e2de0eef9e196e39
https://doi.org/10.1093/ijnp/pyaa083
https://doi.org/10.1093/ijnp/pyaa083
Publikováno v:
Learningmemory (Cold Spring Harbor, N.Y.). 29(3)
NMDA receptors (NMDARs) and AMPA receptors (AMPARs) in amygdala nuclei and the dorsal hippocampus (dHipp) are critical for fear conditioning. Enhancements in synaptic AMPAR expression in amygdala nuclei and the dHipp are critical for fear conditionin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b730b04da9dd8bea0c37df5ba8f755aa
https://pubmed.ncbi.nlm.nih.gov/35169047
https://pubmed.ncbi.nlm.nih.gov/35169047
Publikováno v:
Learn Mem
Clinical and preclinical studies that have examined the neurobiology of persistent fear memory in posttraumatic stress disorder (PTSD) have focused on the medial prefrontal cortex, hippocampus, and amygdala. Sensory systems, the periaqueductal gray (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::239a7916e8d3bead59cf7119b41f3b63
https://doi.org/10.1101/lm.050310.119
https://doi.org/10.1101/lm.050310.119
Autor:
Samantha M. Keller, Marisa Chamness, Dayan Knox, Thomas DePietro, Caroline Lawless, Nina P. David, Briana R. Stanfield, Jennifer M. Staib, Elizabeth K. Schneider
Publikováno v:
Behavioural Brain Research. 341:189-197
Neural circuits via which stress leads to disruptions in fear extinction is often explored in animal stress models. Using the single prolonged stress (SPS) model of post traumatic stress disorder and the immediate early gene (IEG) c-Fos as a measure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::badf8f113f12e4f59d32f23c69c99f89
https://doi.org/10.1016/j.bbr.2017.12.037
https://doi.org/10.1016/j.bbr.2017.12.037
Autor:
Dayan Knox
Publikováno v:
Biological Psychiatry. 89:S48-S49
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2b1f914e481240b7064b29d8f25683d
https://doi.org/10.1016/j.biopsych.2021.02.138
https://doi.org/10.1016/j.biopsych.2021.02.138