Safety of age-dosed, single low-dose primaquine in children with glucose-6-phosphate dehydrogenase deficiency who are infected with Plasmodium falciparum in Uganda and the Democratic Republic of the Congo: a randomised, double-blind, placebo-controlled, non-inferiority trial.

Autor: Taylor WR; Mahidol Oxford Tropical Medicine Clinical Research Unit, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK. Electronic address: bob@tropmedres.ac., Olupot-Olupot P; Mbale Clinical Research Institute, Mbale, Uganda; Department of Public Health, Busitema University, Mbale, Uganda., Onyamboko MA; Kinshasa School of Public Health, University of Kinshasa, Kinshasa, Democratic Republic of the Congo., Peerawaranun P; Mahidol Oxford Tropical Medicine Clinical Research Unit, Mahidol University, Bangkok, Thailand., Weere W; Mbale Clinical Research Institute, Mbale, Uganda., Namayanja C; Mbale Clinical Research Institute, Mbale, Uganda., Onyas P; Mbale Clinical Research Institute, Mbale, Uganda., Titin H; Mbale Clinical Research Institute, Mbale, Uganda., Baseke J; Department of Public Health, Busitema University, Mbale, Uganda., Muhindo R; Mbale Clinical Research Institute, Mbale, Uganda., Kayembe DK; Kinshasa School of Public Health, University of Kinshasa, Kinshasa, Democratic Republic of the Congo., Ndjowo PO; Kinshasa School of Public Health, University of Kinshasa, Kinshasa, Democratic Republic of the Congo., Basara BB; Kinshasa School of Public Health, University of Kinshasa, Kinshasa, Democratic Republic of the Congo., Bongo GS; Kinshasa School of Public Health, University of Kinshasa, Kinshasa, Democratic Republic of the Congo., Okalebo CB; Mbale Clinical Research Institute, Mbale, Uganda., Abongo G; Mbale Clinical Research Institute, Mbale, Uganda., Uyoga S; KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya., Williams TN; KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya; Institute of Global Health Innovation, Imperial College London, London, UK., Taya C; Mahidol Oxford Tropical Medicine Clinical Research Unit, Mahidol University, Bangkok, Thailand., Dhorda M; Mahidol Oxford Tropical Medicine Clinical Research Unit, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Tarning J; Mahidol Oxford Tropical Medicine Clinical Research Unit, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Dondorp AM; Mahidol Oxford Tropical Medicine Clinical Research Unit, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Waithira N; Mahidol Oxford Tropical Medicine Clinical Research Unit, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Fanello C; Mahidol Oxford Tropical Medicine Clinical Research Unit, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Maitland K; KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya; Institute of Global Health Innovation, Imperial College London, London, UK., Mukaka M; Mahidol Oxford Tropical Medicine Clinical Research Unit, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Day NJP; Mahidol Oxford Tropical Medicine Clinical Research Unit, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Publikováno v: The Lancet. Infectious diseases [Lancet Infect Dis] 2023 Apr; Vol. 23 (4), pp. 471-483. Date of Electronic Publication: 2022 Nov 30.