Challenges of Incorporating Digital Health Technology Outcomes in a Clinical Trial: Experiences from PD STAT.

Autor: Day, Jacob O.¹ (AUTHOR) jacobday@doctors.org.uk, Smith, Stephen² (AUTHOR), Noyce, Alastair J.^3,4 (AUTHOR), Alty, Jane^5,6 (AUTHOR), Jeffery, Alison⁷ (AUTHOR), Chapman, Rebecca⁷ (AUTHOR), Carroll, Camille¹ (AUTHOR)

Publikováno v: Journal of Parkinson's Disease. 2022, Vol. 12 Issue 5, p1605-1609. 5p.

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The dopamine D2/D3 receptor agonist quinpirole increases checking-like behaviour in an operant observing response task with uncertain reinforcement: a novel possible model of OCD

Autor: Eagle, Dawn M., Noschang, Cristie, d’Angelo, Laure-Sophie Camilla, Noble, Christie A., Day, Jacob O., Dongelmans, Marie Louise, Theobald, David E., Mar, Adam C., Urcelay, Gonzalo P., Morein-Zamir, Sharon, Robbins, Trevor W.

Publikováno v: Behavioural Brain Research

Highlights • We validate a novel operant model of compulsive checking, relevant to OCD. • The dopamine D2/3 receptor agonist quinpirole selectively increases checking. • Uncertainty increases checking differently following quinpirole treatment.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4a64e2c6984b94eda9b310bd72778383
https://arro.anglia.ac.uk/id/eprint/604060/1/Eagle_2014.pdf

A man with paraesthesia, headache, and vertigo

Autor: Day, Jacob O, Bhatt, Pragnesh

Publikováno v: BMJ: British Medical Journal,

Externí odkaz: https://www.jstor.org/stable/26951854

The dopamine D2/D3 receptor agonist quinpirole increases checking-like behaviour in an operant observing response task with uncertain reinforcement: a novel possible model of OCD.

Autor: Eagle DM; Department of Psychology and Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Site, Cambridge, CB2 3EB, UK. Electronic address: de102@cam.ac.uk., Noschang C; Department of Psychology and Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Site, Cambridge, CB2 3EB, UK., d'Angelo LS; Department of Psychology and Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Site, Cambridge, CB2 3EB, UK., Noble CA; Department of Psychology and Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Site, Cambridge, CB2 3EB, UK., Day JO; Department of Psychology and Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Site, Cambridge, CB2 3EB, UK., Dongelmans ML; Department of Psychology and Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Site, Cambridge, CB2 3EB, UK., Theobald DE; Department of Psychology and Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Site, Cambridge, CB2 3EB, UK., Mar AC; Department of Psychology and Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Site, Cambridge, CB2 3EB, UK., Urcelay GP; Department of Psychology and Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Site, Cambridge, CB2 3EB, UK., Morein-Zamir S; Department of Psychology and Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Site, Cambridge, CB2 3EB, UK., Robbins TW; Department of Psychology and Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Site, Cambridge, CB2 3EB, UK.

Publikováno v: Behavioural brain research [Behav Brain Res] 2014 May 01; Vol. 264, pp. 207-29. Date of Electronic Publication: 2014 Jan 06.