Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Daxiao Cheng"'
Autor:
Lunhao Chen, Daxiao Cheng, Jiachen Chu, Ting Zhang, Zhuoer Dong, Huifang Lou, Liya Zhu, Yijun Liu
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Here we described an experimental protocol for in vivo imaging of macropinocytosis and subsequent intracellular events. By microinjection, we delivered fluorescence dextrans together with or without ATPγS into transparent Drosophila melanogaster emb
Externí odkaz:
https://doaj.org/article/ed0331a6d24d43b49a5d51eea6a44ed4
Autor:
Yi-Jun Liu, Daxiao Cheng, Xiao-Dong Wang, Duo Duan, Shumin Duan, Huifang Lou, Liya Zhu, Junhua Yang, Margaret S. Ho, Sicong Chen, Xingyue Wang, Xia Li, Ting Zhang, Jianhong Luo
Publikováno v:
Science Advances
Protease cathD escapes from late endosomes to cytosol and accelerates actin dynamics.
Organelle transport requires dynamic cytoskeleton remodeling, but whether cytoskeletal dynamics are, in turn, regulated by organelles remains elusive. Here, we
Organelle transport requires dynamic cytoskeleton remodeling, but whether cytoskeletal dynamics are, in turn, regulated by organelles remains elusive. Here, we
Autor:
Duo Duan, Margaret S. Ho, Liya Zhu, Sicong Chen, Xingyue Wang, Daxiao Cheng, Yi-Jun Liu, Zhefeng Gong, Ting Zhang, Xiao-Dong Wang, Cunjin Wu, Shumin Duan, Huifang Lou
Publikováno v:
Cell Research
Cathepsin D (cathD) is traditionally regarded as a lysosomal protease that degrades substrates in acidic compartments. Here we report cathD plays an unconventional role as a cofilin phosphatase orchestrating actin remodeling. In neutral pH environmen
Autor:
Ting Zhang, Liya Zhu, Daxiao Cheng, Xingyue Wang, Qiang Ke, Cunjin Wu, Yi-Jun Liu, Shumin Duan, Huifang Lou, Xiao-Dong Wang
Publikováno v:
Neuroscience Bulletin
The main lysosomal protease cathepsin D (cathD) is essential for maintaining tissue homeostasis via its degradative function, and its loss leads to ceroid accumulation in the mammalian nervous system, which results in progressive neurodegeneration. I