Functional effects of chimeric antigen receptor co-receptor signaling domains in human regulatory T cells.

Autor: Dawson NAJ; Department of Medicine, University of British Columbia, Vancouver, BC V5Z 4H4, Canada.; BC Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada., Rosado-Sánchez I; BC Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada.; School of Biomedical Engineering, University of British Columbia, Vancouver, BC V5Z 4H4, Canada., Novakovsky GE; BC Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, BC V5Z 4H4, Canada., Fung VCW; BC Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada.; Department of Surgery, University of British Columbia, Vancouver, BC V5Z 4H4, Canada., Huang Q; BC Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada.; Department of Surgery, University of British Columbia, Vancouver, BC V5Z 4H4, Canada., McIver E; BC Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada.; Department of Surgery, University of British Columbia, Vancouver, BC V5Z 4H4, Canada., Sun G; BC Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada.; Department of Surgery, University of British Columbia, Vancouver, BC V5Z 4H4, Canada., Gillies J; BC Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada.; Department of Surgery, University of British Columbia, Vancouver, BC V5Z 4H4, Canada., Speck M; BC Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada.; Department of Surgery, University of British Columbia, Vancouver, BC V5Z 4H4, Canada., Orban PC; BC Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada.; Department of Surgery, University of British Columbia, Vancouver, BC V5Z 4H4, Canada., Mojibian M; BC Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada.; Department of Surgery, University of British Columbia, Vancouver, BC V5Z 4H4, Canada., Levings MK; BC Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada. mlevings@bcchr.ca.; School of Biomedical Engineering, University of British Columbia, Vancouver, BC V5Z 4H4, Canada.; Department of Surgery, University of British Columbia, Vancouver, BC V5Z 4H4, Canada.

Publikováno v: Science translational medicine [Sci Transl Med] 2020 Aug 19; Vol. 12 (557).

Engineered Tolerance: Tailoring Development, Function, and Antigen-Specificity of Regulatory T Cells.

Autor: Dawson NAJ; Department of Medicine, University of British Columbia, Vancouver, BC, Canada.; BC Children's Hospital Research Institute, Vancouver, BC, Canada., Vent-Schmidt J; Department of Medicine, University of British Columbia, Vancouver, BC, Canada., Levings MK; BC Children's Hospital Research Institute, Vancouver, BC, Canada.; Department of Surgery, University of British Columbia, Vancouver, BC, Canada.

Publikováno v: Frontiers in immunology [Front Immunol] 2017 Nov 03; Vol. 8, pp. 1460. Date of Electronic Publication: 2017 Nov 03 (Print Publication: 2017).

Regulatory T cells produce profibrotic cytokines in the skin of patients with systemic sclerosis.

Autor: MacDonald KG; Department of Surgery, University of British Columbia, and the Child and Family Research Institute, Vancouver, British Columbia, Canada., Dawson NAJ; Department of Surgery, University of British Columbia, and the Child and Family Research Institute, Vancouver, British Columbia, Canada., Huang Q; Department of Medicine, University of British Columbia, and the Child and Family Research Institute, Vancouver, British Columbia, Canada., Dunne JV; Department of Medicine, University of British Columbia, and the Child and Family Research Institute, Vancouver, British Columbia, Canada; Department of Medicine, University of British Columbia, and St Paul's Hospital, Vancouver, British Columbia, Canada., Levings MK; Department of Surgery, University of British Columbia, and the Child and Family Research Institute, Vancouver, British Columbia, Canada., Broady R; Department of Medicine, University of British Columbia, and the Child and Family Research Institute, Vancouver, British Columbia, Canada. Electronic address: rbroady@mail.ubc.ca.

Publikováno v: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2015 Apr; Vol. 135 (4), pp. 946-955.e9. Date of Electronic Publication: 2015 Feb 10.