Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Dawne N Shelton"'
Autor:
Dawne N Shelton, Prasanthi Bhagavatula, Nathan Sepulveda, Lan Beppu, Shital Gandhi, Dahui Qin, Scott Hauenstein, Jerald Radich
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0265278 (2022)
Chronic myelogenous leukemia (CML) is a hematopoietic stem cell malignancy that accounts for 15-20% of all cases of leukemia. CML is caused by a translocation between chromosomes 9 and 22 which creates an abnormal fusion gene, BCR::ABL1. The amount o
Externí odkaz:
https://doaj.org/article/8f718335a7f54f7a832784608c190d61
Autor:
Wei Yang, Dawne N Shelton, Jennifer R Berman, Bin Zhang, Samantha Cooper, Svilen Tzonev, Eli Hefner, John F Regan
Publikováno v:
BioTechniques, Vol 58, Iss 5, Pp 270-271 (2015)
Targeted therapies in many cancers have allowed unprecedented progress in the treatment of disease. However, routine implementation of genomic testing is constrained due to: 1) limited amounts of sample (pg–ng range) per biological specimen, 2) dia
Externí odkaz:
https://doaj.org/article/e9fdaeb8d82d4bacaaecd7be96db2490
Autor:
Dawne N Shelton, Hubert Fornalik, Traci Neff, Soo Yeun Park, David Bender, Koen DeGeest, Xiaoming Liu, Weiliang Xie, David K Meyerholz, John F Engelhardt, Michael J Goodheart
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40312 (2012)
Endometrial carcinoma is the most common gynecologic cancer, yet the mechanisms underlying this disease process are poorly understood. We hypothesized that Lef1 is required for endometrial gland formation within the uterus and is overexpressed in end
Externí odkaz:
https://doaj.org/article/f478f668d4dc464a96e50da2e8a98216
Autor:
Dawne N. Shelton, Prasanthi Bhagavatula, Nathan Sepulveda, Lan Beppu, Shital Gandhi, Dahui Qin, Scott Hauenstein, Jerald Radich
Publikováno v:
PloS one. 17(3)
Chronic myelogenous leukemia (CML) is a hematopoietic stem cell malignancy that accounts for 15–20% of all cases of leukemia. CML is caused by a translocation between chromosomes 9 and 22 which creates an abnormal fusion gene, BCR::ABL1. The amount
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b392a82d83380fc0399ada70ceb437fc
https://pubmed.ncbi.nlm.nih.gov/35298544
https://pubmed.ncbi.nlm.nih.gov/35298544
Autor:
Martin Kampmann, Ryan Mahling, Jonathan S. Weissman, Hongxing Yang, Mimi Fang, Mignon L. Loh, Miles A. Pufall, Sarah K. Tasian, Ossama Abu-Halawa, Michael C. Bassik, Markus Müschen, Dawne N. Shelton, Karina Kruth
Publikováno v:
Blood. 129:3000-3008
Glucocorticoids (GCs), including dexamethasone (dex), are a central component of combination chemotherapy for childhood B-cell precursor acute lymphoblastic leukemia (B-ALL). GCs work by activating the GC receptor (GR), a ligand-induced transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f6b740b1110942e4625994b3b180f3
https://doi.org/10.1182/blood-2017-02-766204
https://doi.org/10.1182/blood-2017-02-766204
Autor:
Ubaradka G. Sathyanarayana, Kristina Koch, Hestia Mellert, Samantha Cooper, Trudi Foreman, Paula Stonemetz, Scott Thurston, Westen Hahn, Jakkie Greer, Dawne N. Shelton, Dianna Maar, Leisa Jackson, Nicholas F. Dupuis, Gary Pestano, Amanda Weaver
Publikováno v:
The Journal of Molecular Diagnostics. 19:404-416
Nearly 80% of cancer patients do not have genetic mutation results available at initial oncology consultation; up to 25% of patients begin treatment before receiving their results. These factors hinder the ability to pursue optimal treatment strategi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a9996e3d72a3208e4fdea996bcf052
https://doi.org/10.1016/j.jmoldx.2016.11.004
https://doi.org/10.1016/j.jmoldx.2016.11.004
Publikováno v:
Cancer Research. 80:6483-6483
Introduction: Chronic myelogenous leukemia (CML) is a cancer of myeloid cells that accounts for 15-20% of all cases of leukemia. Most CML cases are caused by a translocation between chromosomes 9 and 22 which creates an abnormal fusion gene, BCR-ABL1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8a84e58acbbc1ee3c9c9d8ceedccff6
https://doi.org/10.1158/1538-7445.am2020-6483
https://doi.org/10.1158/1538-7445.am2020-6483
Autor:
Isaac S. Harris, Dawne N. Shelton, Qinglian Tang, Tak W. Mak, Hal Berman, Christopher M Watling, Sam D. Molyneux, Zsuzsanna Izsvák, Pirashaanthy Tharmapalan, Geir Kjetil Sandve, Swneke D. Bailey, Brendan C. Dickson, Yang W. Shao, Mathieu Lupien, Paul Waterhouse, Jay S. Wunder, Xiaoyang Zhang, Rama Khokha
Publikováno v:
Nature Genetics. 52:464-464
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8be1c9efce8169b9a918ea46f21a5661
https://doi.org/10.1038/s41588-020-0589-2
https://doi.org/10.1038/s41588-020-0589-2
Publikováno v:
Methods in Molecular Biology ISBN: 9781493977765
Telomerase is a cellular RNA template-dependent reverse transcriptase that adds telomere repeats to the 3’ ends of chromosomes. Telomerase is expressed almost universally in tumor cells (>85%) to maintain telomere length, thus providing the ability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b11d97281fec6a5e9176c40d3a8082d
https://doi.org/10.1007/978-1-4939-7778-9_29
https://doi.org/10.1007/978-1-4939-7778-9_29
Autor:
Dawne N. Shelton, Jyothirmayee S. Tadepalli, Manohar R. Furtado, Yilong Zhang, Anna C. Pavlick, Sarah A. Weiss, Eric Robinson, Iman Osman, George Karlin-Neumann, David Polsky, Yongzhao Shao, Cindy Spittle, Gregory Chang
Publikováno v:
Molecular Oncology. 10:157-165
Melanoma lacks a clinically useful blood-based biomarker of disease activity to help guide patient management. To determine whether measurements of circulating, cell-free, tumor-associated BRAF(mutant) and NRAS(mutant) DNA (ctDNA) have a higher sensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb83ffbbdecee8cfc0615fe217cc0705
https://doi.org/10.1016/j.molonc.2015.09.005
https://doi.org/10.1016/j.molonc.2015.09.005