Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Dawn Zinyk"'
Autor:
Hussein Ghazale, EunJee Park, Lakshmy Vasan, James Mester, Fermisk Saleh, Andrea Trevisiol, Dawn Zinyk, Vorapin Chinchalongporn, Mingzhe Liu, Taylor Fleming, Oleksandr Prokopchuk, Natalia Klenin, Deborah Kurrasch, Maryam Faiz, Bojana Stefanovic, JoAnne McLaurin, Carol Schuurmans
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Direct neuronal reprogramming, the process whereby a terminally differentiated cell is converted into an induced neuron without traversing a pluripotent state, has tremendous therapeutic potential for a host of neurodegenerative diseases. While there
Externí odkaz:
https://doaj.org/article/0eb03c295a474e0c9abfd4326919866b
Autor:
Yacine Touahri, Luke Ajay David, Joseph Hanna, Satoshi Okawa, Hedy Liu, Yucheng Xiao, Alissa Pak, Yaroslav Ilnytskyy, Edwin van Oosten, Nobuhiko tachibana, Lata Adnani, Jiayi Zhao, Mary Hoffman, Rajiv Dixit, Dawn Zinyk, Cynthia J. Guidos, Volker Enzmann, Pengpeng Bi, Isabelle Aubert, Laurent Journot, Igor Kovalchuk, Yves Sauvé, Jeff Biernaskie, Chao Wang, Antonio del Sol, Carol Janine Schuurmans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71d25af604eeefe9fc3b34d7ffa7aa67
https://doi.org/10.2139/ssrn.4423987
https://doi.org/10.2139/ssrn.4423987
Publikováno v:
Bio-Protocol, Vol 7, Iss 3 (2017)
All seven retinal cell types that make up the mature retina are generated from a common, multipotent pool of retinal progenitor cells (RPCs) (Wallace, 2011). One way that RPCs know when sufficient numbers of particular cell-types have been generated
Externí odkaz:
https://doaj.org/article/5acad1b27dd94b4cafbf1ff07eed03a3
Autor:
Imrul Faisal, Eko Raharjo, Carol Schuurmans, Dawn Zinyk, Yaroslav Ilnytskyy, Antonio del Sol, Ana-Maria Oproescu, Saiqun Li, Diogo S. Castro, Jinghua Gao, Vladimir Espinosa Angarica, Colette Dehay, Rajiv Dixit, Deborah M. Kurrasch, Satoshi Okawa, Jung-Woong Kim, Wei Wu, Jennifer A. Chan, Yacine Touahri, Lata Adnani, Sisu Han, Grey Wilkinson, Veronique Cortay, Waleed Rahmani, Faizan Malik, Anand Swaroop, Jeff Biernaskie, Vorapin Chinchalongporn, Igor Kovalchuk, Matthew Brooks
SUMMARYTransition from smooth, lissencephalic brains to highly-folded, gyrencephalic structures is associated with neuronal expansion and breaks in neurogenic symmetry. Here we show thatNeurog2andAscl1proneural genes regulate cortical progenitor cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65f9b3a83678180711b2d7ac5dbb3d92
https://doi.org/10.1101/2020.09.22.307058
https://doi.org/10.1101/2020.09.22.307058
Autor:
Anjali Balakrishnan, Lata Adnani, Vorapin Chinchalongporn, Lakshmy Vasan, Oleksandr Prokopchuk, Myra Chen, Ahmed El-Sehemy, Thomas Olender, Yacine Touahri, Shiekh Tanveer Ahmad, Rehnuma Islam, Sajeevan Sujanthan, Dawn Zinyk, Lacrimioara Comanita, Boris Kan, Taylor Fleming, Hon Leong, Cindi Morshead, Marjorie Brand, Valerie Wallace, Jennifer Chan, Carol Schuurmans
Oligodendrogliomas are lower-grade, slow-growing gliomas that are ultimately fatal. Although driver mutations are known, the mechanisms underlying their signature slow growth rates are poorly understood. We found evidence for intra-tumoral interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27b0ef9d126c6e1faf6198363b23513d
https://doi.org/10.21203/rs.3.rs-39873/v1
https://doi.org/10.21203/rs.3.rs-39873/v1
Autor:
Ahmed El-Sehemy, Yacine Touahri, Myra J. Chen, Thomas Olender, Carol Schuurmans, Cindi M. Morshead, Taylor Fleming, Jennifer A. Chan, Dawn Zinyk, Sajeevan Sujanthan, Shiekh Tanveer Ahmad, Valerie A. Wallace, Rehnuma Islam, Oleksandr Prokopchuk, Lata Adnani, Vorapin Chinchalongporn, Lacrimioara Comanita, Hon Leong, Marjorie Brand, Lakshmy Vasan, Anjali Balakrishnan, Boris Kan
Oligodendrogliomas are lower-grade, slow-growing gliomas that are ultimately fatal. Although driver mutations are known, the mechanisms underlying their signature slow growth rates are poorly understood. We found evidence for intra-tumoral interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::811a924dc60231154e348099bab38ea1
https://doi.org/10.1101/2020.07.14.202200
https://doi.org/10.1101/2020.07.14.202200
Autor:
Faizan Malik, Jennifer A. Chan, Anand Swaroop, Sisu Han, Jeff Biernaskie, Diogo S. Castro, Saiqun Li, Veronique Cortay, Imrul Faisal, Deborah M. Kurrasch, Lata Adnani, Wei Wu, Ana-Maria Oproescu, Jung-Woong Kim, Carol Schuurmans, Colette Dehay, Satoshi Okawa, Rajiv Dixit, Yacine Touahri, Yaroslav Ilnytskyy, Dawn Zinyk, Vladimir Espinosa Angarica, Antonio del Sol, Waleed Rahmani, Jinghua Gao, Igor Kovalchuk, Matthew Brooks, Vorapin Chinchalongporn, Eko Raharjo, Grey Wilkinson
Publikováno v:
SSRN Electronic Journal.
Transition from smooth, lissencephalic brains to highly-folded, gyrencephalic structures is associated with neuronal expansion and breaks in neurogenic symmetry. Here we show that Neurog2 and Ascl1 proneural genes regulate cortical progenitor cell di
Autor:
Robert Cantrup, Rajiv Dixit, Elena Palmesino, Stephan Bonfield, Tarek Shaker, Nobuhiko Tachibana, Dawn Zinyk, Sarah Dalesman, Kazuhiro Yamakawa, William K Stell, Rachel O Wong, Benjamin E Reese, Artur Kania, Yves Sauvé, Carol Schuurmans
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32795 (2012)
The retina has a unique three-dimensional architecture, the precise organization of which allows for complete sampling of the visual field. Along the radial or apicobasal axis, retinal neurons and their dendritic and axonal arbors are segregated into
Externí odkaz:
https://doaj.org/article/872d3e46177b46439adfd9e8ab52d3be
Autor:
Imrul Faisal, Rajiv Dixit, Carol Schuurmans, Adam Sivitilli, Jennifer A. Chan, Lata Adnani, Grey Wilkinson, Ana-Maria Oproescu, Veronique Cortay, Hussein Ghazale, Antonio del Sol, Sisu Han, Yaroslav Ilnytskyy, Eko Raharjo, Vorapin Chinchalongporn, Waleed Rahmani, Faizan Malik, Igor Kovalchuk, Yacine Touahri, Diogo S. Castro, Vladimir Espinosa Angarica, Matthew Brooks, Lakshmy Vasan, Dawn Zinyk, Lígia Tavares, Luke Ajay David, Satoshi Okawa, Anand Swaroop, Jeff Biernaskie, Wei Wu, Liliana Attisano, Colette Dehay, Saiqun Li, Jinghua Gao, Deborah M. Kurrasch, Jung-Woong Kim
Publikováno v:
Neuron
Neuron, Elsevier, 2021, 109 (18), pp.2847-2863.e11. ⟨10.1016/j.neuron.2021.07.007⟩
Neuron, Elsevier, 2021, 109 (18), pp.2847-2863.e11. ⟨10.1016/j.neuron.2021.07.007⟩
International audience; Asymmetric neuronal expansion is thought to drive evolutionary transitions between lissencephalic and gyrencephalic cerebral cortices. We report that Neurog2 and Ascl1 proneural genes together sustain neurogenic continuity and
Autor:
François Guillemot, Deborah M. Kurrasch, Anjali Balakrishnan, Rajiv Dixit, Daniel J. Dennis, Dawn Zinyk, Carol Schuurmans, Olivier Britz, Marjorie Brand, Sisu Han, Yacine Touahri, Thomas Olender
Publikováno v:
Development.
Neural progenitors undergo temporal identity transitions to sequentially generate the neuronal and glial cells that make up the mature brain. Proneural genes have well-characterised roles in promoting neural cell differentiation and subtype specifica